Breast Cancer
Effects of the Zhikang capsule on healing of the flap after radical breast cancer surgery
Authors: C. Cheng, Y. Lv, E. Zhang, T. Yan, C. Li, D.-X. Hou and J.-H. Li
This study aimed to investigate the effect and mechanism of trauma flap healing promoted by the Zhikang capsule after radical breast cancer surgery. The enrolled breast cancer patients were randomly divided into two groups: treatment and observation. The patients in the treatment group were treated with the Zhikang capsule in addition to the conventional .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.18.2
- DOI:
- 10.4238/2015.May.18.2
Effect of calcitonin on anastrozole-induced bone pain during aromatase inhibitor therapy for breast cancer
Authors: P. Liu, D.Q. Yang, F. Xie, B. Zhou and M. Liu
This study aimed to investigate calcitonin as an effective therapy for osteoporosis in patients with bone pain during the anastrozole treatment of breast cancer. Ninety-one patients, who were on anastrozole treatment for breast cancer and also suffered anastrozole-induced bone pain, were randomly divided into two groups: the c.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.24.7
- DOI:
- 10.4238/2014.July.24.7
Association of dietary intake of folate and MTHFR genotype with breast cancer risk
Authors: Z.G. Wang, W. Cui, L.F. Yang, Y.Q. Zhu and W.H. Wei
We conducted a hospital-based case-control study to investigate the associations of dietary intake of folate and MTHFR C677T and A1298C polymorphisms with breast cancer in a Chinese population. A 1:1-matched case-control study was conducted. Two hundred and thirty patients who were newly diagnosed and histologically confirmed .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.24.24
- DOI:
- 10.4238/2014.July.24.24
1236 C/T and 3435 C/T polymorphisms of the ABCB1 gene in Mexican breast cancer patients
Authors: S.A. Gutierrez-Rubio, A. Quintero-Ramos, A. Dur�¡n-C�¡rdenas,R.A. Franco-Topete, J.M. Castro-Cervantes, A. Oceguera-Villanueva, L.M. Jim�©nez-P�©rez, L.M.A. Balderas-Pe�±a, G. Morgan-Villela,A. Del-Toro-Arreola and A. Daneri-Navarro
MDR1, which is encoded by the ABCB1 gene, is involved in multidrug resistance (hydrophobic), as well as the elimination of xenotoxic agents. The association between ABCB1 gene polymorphisms and breast cancer risk in different populations has been described previously; however, the results have been inconclusive. In this study, we examined the association bet.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.13.3
- DOI:
- 10.4238/2015.February.13.3
Lack of association between the aryl hydrocarbon receptor rs2066853 polymorphism and breast cancer: A meta-analysis on Ahr polymorphism and breast cancer
Authors: Y. Li, H.Z. Qin, Q. Song, X.D. Wu and J.H. Zhu
Published data regarding the association between aryl hydrocarbon receptor (Ahr) rs2066853 polymorphism and the risk of breast cancer shows conflicting results. We performed a meta-analysis on 2999 patients and 3050 controls from three related case-control studies to estimate the association between Ahr rs2066853 polymorphism and the risk of breast cancer.. Read More»
- Genet. Mol. Res. 14(4):
- 2015
- DOI:
- 10.4238/2015
Investigation on the association between NLRP3 gene polymorphisms and susceptibility to primary gout
Authors: L.F. Wang, Y.J. Ding, Q. Zhao, X.L. Zhang
We conducted a case-control study to investigate the association between 3 common NALP3 polymorphisms (rs10754558, rs7512998, and rs12137901) and the susceptibility to primary gout. A total of 320 patients with primary gout and 320 controls were included in this study. The genotyping of NALP3 rs10754558, rs7512998, and rs12137901 were conducted by polymer.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.
- DOI:
- 10.4238/2015.
Association between MTHFR 677C/T and 1298A/C gene polymorphisms and breast cancer risk
Authors: X.F. Zhang, T. Liu, Y. Li and S. Li
ABSTRACT. We performed a case-control study to investigate the association between single nucleotide polymorphisms in the MTHFR gene (677C/T and 1298A/C) and risk of breast cancer. This case-control study included 216 breast cancer cases and 216 controls. The MTHFR 677C/T and 1298A/C gene polymorphisms were assessed by polymerase chain reaction restrictio.. Read More»
- Genet. Mol. Res. 14(4):
- 2015
- DOI:
- 10.4238/2015
Clinical applications of internal heat source analysis for breast cancer identification
Authors: F. Han, C.W. Liang, G.L. Shi, L. Wang and K.Y. Li
Nondestructive preoperative breast imaging techniques are widely used for breast cancer testing and diagnosis. This study aimed to evaluate the feasibility and efficacy of quantitative diagnosis via the thermal analysis of abnormal metabolism. Nine hundred forty-eight women who underwent breast biopsy from 2009 to 2013 were investigated. Thermal analysis .. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.13.24
- DOI:
- 10.4238/2015.February.13.24
Association of CYP2C19*3 gene polymorphism with breast cancer in Chinese women
Authors: C.Q. Gan, X.Y. Wang, Y.D. Cao, W.X. Ye, H. Liu and Y.Y. Sun
Cytochrome P450 (CYP) 2C19 metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids, which significantly promote proliferation of cancer cells in vitro and in vivo. We looked for a possible association between human CYP2C19*3 gene polymorphism and breast cancer in the Chinese Han population. In a Chinese H.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.5.3
- DOI:
- 10.4238/2011.December.5.3
Elimination of breast tumor-associated chondroitin sulfate promotes metastasis
Authors: R.D. Prinz, C.M. Willis, A. Viloria-Petit and M. Kl�¼ppel
Breast cancer is one of the leading causes of cancer-related deaths amongst women in the USA. The tumor microenvironment has been suggested to be an attractive therapeutic target for treatment of cancers. The glycosaminoglycan chondroitin sulfate, as part of the cellular microenvironment, consists of long linear chains of repe.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.8.9
- DOI:
- 10.4238/2011.December.8.9