Cancer
Association of chemotactic factor receptor 5 gene with breast cancer
Authors: Y. Zhang1, F.Y. Meng2, W.L. Li1, C.X. Zhou1, Z. Guan1 and H.Y. Fan2
We designed a 2-stage study to investigate chemotactic factor receptor 5 (CCR5) gene expression in breast cancer tissues and axillary lymph nodes and analyze the association between the CCR5-Δ32 gene polymorphism and the clinical features and prognosis of breast cancer patients. The first stage examined 72 cases of invasive ductal carcinoma and axil.. Read More»
- Genet. Mol. Res. 13(3):
- 2013.November.7.4
- DOI:
- 10.4238/2013.November.7.4
Clinical application of carbon nanoparticle lymph node tracer in the VI region lymph node dissection of differentiated thyroid cancer
Authors: S.P. Sun, Y. Zhang, Z.Q. Cui, Q. Chen, W. Zhang, C.X. Zhou, P.P. Xie and B.G. Liu
The application and clinical significance of carbon nanoparticle lymph tracer in the VI region (central region) lymph node dissection of differentiated thyroid cancer was investigated. Eighty patients with differentiated thyroid cancer were equally divided into the carbon nanoparticle-marked group (ipsilateral thyroid injectio.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.April.30.4
- DOI:
- http://dx.doi.org/10.4238/2014.April.30.4
Expression profiles of variation integration genes in bladder urothelial carcinoma
Authors: J.M. Wang, Y.Q. Wang, Z.L. Gao, J.T. Wu, B.K. Shi and C.C. Yu
Bladder cancer is a common cancer worldwide and its incidence continues to increase. There are approximately 261,000 cases of bladder cancer resulting in 115,000 deaths annually. This study aimed to integrate bladder cancer genome copy number variation information and bladder cancer gene transcription level expression data to .. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.April.30.9
- DOI:
- http://dx.doi.org/10.4238/2014.April.30.9
Preset ureter catheter in laparoscopic radical hysterectomy of cervical cancer
Authors: L. Han, R. Cao, J.Y. Jiang, Y. Xi, X.C. Li and G.H. Yu
The aim of this study was to evaluate the clinical efficacy of a temporary ureteral catheter in preventing iatrogenic ureteral damage in cervical cancer patients undergoing laparoscopic radical hysterectomy. All cases had confirmed diagnoses of cervical cancer preoperatively between December 2008 and December 2012 in our hospi.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.9.6
- DOI:
- http://dx.doi.org/10.4238/2014.May.9.6
Role of XRCC1 and ERCC5 polymorphisms on clinical outcomes in advanced non-small cell lung cancer
Authors: D. Liu, J. Wu, G.Y. Shi, H.F. Zhou and Y. Yu
We aimed to assess the role of polymorphisms of the XRCC1 Arg194Trp, XRCC1 Arg399Gln, ERCC5 His1104Asp, and ERCC5 His46His genes on clinical outcomes of advanced non-small cell lung cancer (NSCLC) patients receiving platinum-based chemotherapy regimens. A total of 378 NSCLC patients were asked to participate within 1 month aft.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.17.6
- DOI:
- 10.4238/2014.April.17.6
Association analysis of colorectal cancer susceptibility variants with gastric cancer in a Chinese Han population
Authors: C.-P. Zhou, H.-Z. Pan, F.-X Li, N.-Y. Hu, M. Li and X.-X. Yang
Evidence suggests that some genetic variants are risk factors for both colorectal cancer (CRC) and gastric cancer (GC). Thus, we selected 12 reported single nucleotide polymorphisms (SNPs) from genome-wide association studies of CRC and conducted this case-control study to assess the associations between these SNPs and the ris.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.9.10
- DOI:
- http://dx.doi.org/10.4238/2014.May.9.10
Expression of ERCC1 and BRCA1 predict the clinical outcome of non-small cell lung cancer in patients receiving platinum-based chemotherapy
Authors: T.B. Wang, N.L. Zhang, S.H. Wang, H.Y. Li, S.W. Chen and Y.G. Zheng
We examined mRNA expression levels of ERCC1, BRCA1, RRM1, and human β-tubulin-III (TUBB3) in non-small-cell lung carcinoma (NSCLC) patients and investigated the association between expression of these genes and the clinical outcome of NSCLC treatment. A total of 366 patients who underwent surgery for NSCLC were included i.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.9.15
- DOI:
- http://dx.doi.org/10.4238/2014.May.9.15
Apoptotic effects of proteasome and histone deacetylase inhibitors in prostate cancer cell lines
Authors: I. Kiliccioglu, E. Konac, N. Varol, S. Gurocak and C. Yucel Bilen
Prostate cancer is one of the most common types of urological cancers. Despite the implementation of effective radiotherapy and chemotherapy methods, prostate cancer cells can still show resistance to treatment. In recent years, a combination of proteasome and histone deacetylase inhibitors has been used to treat various malig.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.9.17
- DOI:
- http://dx.doi.org/10.4238/2014.May.9.17
Screening of the residual normal ovarian tissue adjacent to orthotopic epithelial ovarian carcinomas in nude mice
Authors: G.H. Zhu, S.T. Wang, M.Z. Yao, J.H. Cai, C.Y. Chen, Z.X. Yang, L. Hong and S.Y. Yang
The objective of this study was to explore the feasibility and methods of screening the residual normal ovarian tissue adjacent to orthotopic ovarian carcinomas in nude mice. Human epithelial ovarian cancer cells (OVCAR3) were subcutaneously implanted for a tumor source and ovarian orthotopic transplantation. The cancer tissue.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.16.6
- DOI:
- 10.4238/2014.April.16.6
Polymorphisms in the XRCC1 gene are associated with treatment response to platinum chemotherapy in advanced non-small cell lung cancer patients based on meta-analysis
Authors: L. Li, C. Wan and F.Q. Wen
X-ray repair cross complementing group 1(XRCC1) polymorphisms have been implicated in interindividual variability of efficacy of platinum chemotherapy for treating non-small cell lung cancer (NSCLC); however, results of different studies have been inconsistent. We conducted a meta-analysis to investigate the association betwee.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.16.1
- DOI:
- http://dx.doi.org/10.4238/2014.May.16.1