Cancer
Value of diffusion weighted imaging in the differential diagnosis of benign and malignant breast lesions at 3.0T MRI
Authors: X.Y. Jiang, Q.Z. Xie, X.S. Cao, T. Gao, C.Y. Xing and X.L. Li
The aim of this study was to investigate the correlation between apparent diffusion coefficients (ADCs), the relative apparent diffusion coefficient (rADC), and the pathological prognostic factor human epidermal growth factor receptor 2 (HER-2) in patients with breast cancer. A total of 64 women with breast cancer underwent br.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.26.15
- DOI:
- 10.4238/2014.September.26.15
Overregulation of microRNA-212 in the poor prognosis of esophageal cancer patients
Authors: B. Qi, S.G. Liu, X.G. Qin, W.J. Yao, J.G. Lu, L. Guo, T.Y. Wang, H.C. Li and B.S. Zhao
There have been few reports evaluating the expression and function of the microRNA miR-212 in esophageal cancer. The aim of this study was to investigate the relationship between miR-212 expression and clinicopathological factors and prognoses of esophageal cancer. MicroRNA was extracted from 46 esophageal cancer patients usin.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.26.18
- DOI:
- 10.4238/2014.September.26.18
Relationship between genetic polymorphisms of DNA ligase 1 and non-small cell lung cancer susceptibility and radiosensitivity
Authors: H. Tian, X. He, L. Yin, W.J. Guo, Y.Y. Xia and Z.X. Jiang
The aim of this study was to examine the relationship between genetic polymorphisms in DNA ligase 1 (LIG1) and nonsmall cell lung cancer (NSCLC) susceptibility and radiosensitivity in a Chinese population. This was a case-control study that included 352 NSCLC patients and 448 healthy controls. Polymerase chain reactionrestriction fragment length polymorph.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.26.14
- DOI:
- 10.4238/2015.June.26.14
Tristetraprolin: a novel mediator of the anticancer properties of resveratrol
Authors: C. Li, C. Tang and G. He
Resveratrol is a natural compound that exhibits anticancer properties. Previous studies have proved that it can inhibit the proliferation of breast cancer cell lines and upregulate some cytokines such as cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF). The initiation and progression of cancer are associa.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027213
- DOI:
- 10.4238/gmr.15027213
Association of CYP1A1 MspI polymorphism with oral cancer risk in Asian populations: a meta-analysis
Authors: J.L. Xu, R. Xia, L. Sun, X. Min, Z.H. Sun, C. Liu, H. Zhang and Y.M. Zhu
Numerous studies regarding the association between the CYP1A1 MspI polymorphism and oral cancer risk in Asian populations have shown controversial results. To get a more precise estimation of this relationship, we conducted a comprehensive meta-analysis. PubMed, the Cochrane Library, Elsevier Science Direct, Web of Knowledge, .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027688
- DOI:
- 10.4238/gmr.15027688
Decreased miR-452 expression in human colorectal cancer and its tumor suppressive function
Authors: T. Tang, G.C. Zhang, C.F. Li, Y.F. Liu and W.Y. Wang
-.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027730
- DOI:
- 10.4238/gmr.15027730
HNF1b is involved in prostate cancer risk via modulating androgenic hormone effects and coordination with other genes
Authors: Y.L. Hu, D. Zhong, F. Pang, Q.Y. Ning, Y.Y. Zhang, G. Li, J.Z. Wu and Z.N. Mo
Prostate cancer is one of the most commonly diagnosed male malignancies. Genome wide association studies have revealed HNF1b to be a major risk gene for prostate cancer susceptibility. We examined the mechanisms of involvement of HNF1b in prostate cancer development. We integrated data from Gene Expression Omnibus prostate cancer genes from the Dragon Dat.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.25.4
- DOI:
- 10.4238/2013.April.25.4
ERCC1 C118T polymorphism has predictive value for platinum-based chemotherapy in patients with late-stage bladder cancer
Authors: Z.C. Xu, H.Z. Cai, X. Li, W.Z. Xu, T. Xu, B. Yu, Q. Zou and L. Xu
This study aims to investigate the association between ERCC1 codon C118T polymorphism and the response rate of platinum-based chemotherapy in patients with late-stage bladder cancer. A total of 41 eligible patients histologically confirmed as having stage IV muscle-invasive transitional cell carcinoma of the bladder were treat.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027801
- DOI:
- 10.4238/gmr.15027801
Clinical significance of CTHRC1 protein expression in human cancers: a meta-analysis
Authors: S.F. Wang, Z. Yin, J.J. Yin, W. Zhang and C.G. Dong
The aim of this meta-analysis was to investigate the overall diagnostic and prognostic values of CTHRC1 expression in human cancer development. Based on the inclusion and exclusion criteria, 8 cohort studies were included in the meta-analysis. The data were extracted, and analyses were performed using a random-effects model. S.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027855
- DOI:
- 10.4238/gmr.15027855
Identification of microRNAs as diagnostic biomarkers in screening of head and neck cancer: a meta-analysis
Authors: M. Zhang, L.J. Zhao, W.Q. Liang and Z.P. Mao
Head and neck cancer (HNC) is one of the most prevalent cancers; it is often diagnosed at its advanced stage and has a low 5-year survival rate. Evidence suggests that noninvasive biomarker microRNAs (miRNAs) are valuable for early diagnosis of HNC. This meta-analysis assessed the diagnostic value of miRNAs in HNC detection. A systematic literature search.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.11.3
- DOI:
- 10.4238/2015.December.11.3