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Cd133

Human Genetics   Research Article

Targeting effect of microRNA on CD133 and its impact analysis on proliferation and invasion of glioma cells

Authors: C. Zhao, Z.G. Ma, S.L. Mou, Y.X. Yang, Y.H. Zhang, W.C. Yao

MiR-200b, a member of the microRNA-200 family, has been identified to be capable of suppressing glioma cell growth through targeting CREB1 or CD133. However, whether miR-200b affects the biological behavior (proliferation, invasion, and migration) of glioma cells is poorly understood. The aim of this study was to evaluate the .. Read More»

Genet. Mol. Res. 16(1):
gmr16019281
DOI:
10.4238/gmr16019281
Human Genetics   Research Article

High expression of HIF-2�?± and its anti-radiotherapy effect in lung cancer stem cells

Authors: J.C. Sun, F. He, W. Yi, M.H. Wan, R. Li, X. Wei, R. Wu and D.L. Niu

Hypoxia-inducible factor-2 alpha (HIF-2α) has been shown to regulate cell stemness, although the expression and effects of HIF-2α in lung cancer stem cells remained unclear. This study investigated HIF-2α expression in lung cancer stem cells, as well as the relationship between HIF-2α expression and radioresistance in lung cancer c.. Read More»

Genet. Mol. Res. 14(4):
2015.December.22.37
DOI:
10.4238/2015.December.22.37