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Chromosome

Human Genetics   Research Article

A novel polymorphic Alu insertion embedded in a LINE 1 retrotransposon in the human X chromosome (DXS225): identification and worldwide population study

Authors: Rinaldo Wellerson Pereira, Simone Silva dos Santos and S�©rgio Danilo Junho Pena

We describe a novel polymorphic Alu insertion (DXS225) on the human X chromosome (Xq21.3) embedded into an L1 retrotransposon. The DXS225 polymorphism was genotyped in 684 males from the CEPH Human Genome Diversity Panel. This insertion was found in all regions of the globe, suggesting that it took place before modern humans s.. Read More»

Genet. Mol. Res. 5(1):
Plant Genetics   Research Article

Environmental variations drive polyploid evolution in neotropical Eugenia species (Myrtaceae)

Authors: R.M. Silveira, R.M. Machado, E.R. Forni-Martins, C.F. Verola and I.R. Costa

Polyploidy is one of the most important mechanisms of speciation and diversification in plant evolution. Polyploidy results in genetic variation among individuals of the same species and even between populations, and may be responsible for differences in environmental tolerance between populations of the same species. This stu.. Read More»

Genet. Mol. Res. 15(4):
gmr15048842
DOI:
10.4238/gmr15048842
Human Genetics   Research Article

Genetic linkage analysis of oral lichen planus in a Chinese family

Authors: Z. Wang, H. Yao, B. Cui, G. Ning and G.Y. Tang

Oral lichen planus (OLP) is a common oral inflammatory disease affecting about 1-2% of the general adult population. As with European families who are diagnosed with OLP, the Chinese family who we studied was diagnosed with a severe form of oral reticular and erosive lesions; moreover, two of the five affected individuals deve.. Read More»

Genet. Mol. Res. 10(3):
vol10-3gmr1137
DOI:
10.4238/vol10-3gmr1137
Animal Genetics   Research Article

Potential control of Aedes aegypti (Diptera: Culicidae) with Piper aduncum L. (Piperaceae) extracts demonstrated by chromosomal biomarkers and toxic effects on interphase nuclei

Authors: M.S. Rafael, W.J. Hereira-Rojas, J.J. Roper, S.M. Nunomuraand W.P. Tadei

Dillapiol, a phenylpropanoid isolate from essential oils of leaves of Piper aduncum (Piperaceae), has insecticidal, fungicidal and antimicrobial activities. The insecticidal activity of dil lapiol was tested in vivo on the larvae and pupae of Aedes aegypti, the mosquito vector of dengue. Specifically, the effect of dillapiol o.. Read More»

Genet. Mol. Res. 7(3):
vol7-3gmr481
DOI:
10.4238/vol7-3gmr481
Human Genetics   Research Article

Structure and polymorphism of 16 novel Y-STRs in Chinese Han Population

Authors: G.Q. Zhang S.Y. Yang L.L. Niu D.W. Guo

Y-chromosome short tandem repeats (Y-STRs) are useful tools for identifying paternity origin and male-female mixed samples because of their male-specificity, haploid inheritance and relatively simplicity. We focused on novel Y-STRs deposited in the human Genome database from DYS708 to DYS726. We typed 16 male-specific Y-STRs from males of a Chinese Han popul.. Read More»

Genet. Mol. Res. 11(4):
2012.October.11.1
DOI:
10.4238/2012.October.11.1
Animal Genetics   Research Article

Heterochromatin and chromosome evolution: a FISH probe of Cebus apella paraguayanus (Primate: Platyrrhini) developed by chromosome microdissection

Authors: Mariela Nieves, Mar�­a M�¼hlmann and Marta Dolores Mudry

Neotropical Primate karyotypes are highly variable, particularly in the heterochromatic regions, not only regarding the amount of heterochromatin, but also the composition. G and C banding and FISH techniques provide useful information to characterize interspecific relationships. We used chromosome microdissection to develop a.. Read More»

Genet. Mol. Res. 4(4):
Microbial Genetics   Research Article

Cytogenetic and genotoxic effects of the insecticides, imidacloprid and methamidophos

Authors: N. Ulku Karabay and M. Gunnehir Oguz

We examined the cytogenetic and genotoxic effects of the neonicotinoid insecticide imidacloprid and the organophosphate insecticide methamidophos, when administered alone or in combination. These insecticides were tested with the bone marrow chromosome aberration assay and micronucleus test in rats and by the bacterial mutatio.. Read More»

Genet. Mol. Res. 4(4):
Animal Genetics   Research Article

Localization of rDNA sites in holocentric chromosomes of three species of triatomines (Heteroptera, Triatominae)

Authors: Grasiela Dias de Campos Severi-Aguiar and Maria Terc�­lia Vilela de Azeredo-Oliveira

Chromatin organization in the holocentric chromosomes of three triatomines species was cytologically studied by fluorescent in situ hybridization with a 45S rDNA probe of Drosophila melanogaster to localize ribosomal genes. In Triatoma tibiamaculata, metaphases I showed telomeric highlights in a single, larger bivalent. In T. .. Read More»

Genet. Mol. Res. 4(4):
Microbial Genetics   Research Article

Genotoxic effects of rotenone on cultured lymphocytes

Authors: Patr�­cia Danielle Lima de Lima, Elizabeth Sumi Yamada, Edmar Tavares da Costa, Claudia do O. Pessoa, Silvia Helena Barem Rabenhorst, Marcelo de Oliveira Bahia, Pl�­nio Cerqueira Cardoso, Raquel Alves Santos, Marilia de Arruda Cardoso Smith and Rommel Rodr�­guez Burbano

Rotenone is a heterocyclic compound widely used as an insecticide, acaricide and piscicide. Its toxicity is mainly caused by the inhibition of mitochondrial respiratory processes and ATP production, resulting in the generation of reactive oxygen species. Reactive oxygen species can interact with DNA, RNA and proteins, leading .. Read More»

Genet. Mol. Res. 4(4):
Human Genetics   Research Article

New chromosomal evidence for the origin of Triatoma infestans populations from Brazil

Authors: N.P. Pereira, K.C.C. Alevi, J.A. Rosa and M.T.V. Azeredo-Oliveira

In this study, the karyometry of different Triatoma infestans populations from different states of Brazil was analyzed and compared with those of a population from Cochabamba. No significant differences were found between the population from Cochabamba and those from Brazil. These results are consistent with the origin of the T. infestans populations of B.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038303
DOI:
10.4238/gmr.15038303