Chromosome
Loss of the AZFc region due to a human Y-chromosome microdeletion in infertile male patients
Authors: L.K. Pandey, S. Pandey, J. Gupta and A.K. Saxena
Infertility is a major reproductive health threat; the frequency of male infertility due to Y-chromosome microdeletions is 13-18% in the human population; these microdeletions involve recurrent loss of three non-overlapping regions designated as AZFa, AZFb and AZFc, associated with spermatogenic failure. Several contradictory .. Read More»
- Genet. Mol. Res. 9(2):
- vol9-2gmr836
- DOI:
- 10.4238/vol9-2gmr836
Mitotic and meiotic behavior of rye chromosomes in wheat - Psathyrostachys huashanica amphiploid x triticale progeny
Authors: Q. Xie, H. Kang, D.L. Sparkes, S. Tao, X.M. Fan, L. Xu, X. Fan, L. Sha, H. Zhang, Y. Wang, J. Zeng and Y. Zhou
The dynamics of rye chromosomes during mitosis and meiosis was analyzed in a subset comprising 33 F3 lines from the cross of wheat, Psathyrostachys huashanica amphiploid (AABBDDNsNs) and hexaploid triticale (AABBRR), as visualized by genomic in situ hybridization. The results indicated that 31 of the total lines contained 4-14 rye chromosomes. Twenty-eigh.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.January.4.16
- DOI:
- 10.4238/2013.January.4.16
Karyotype of Philodryas nattereri and Philodryas olfersii with a comparative analysis of the Dipsadidae family
Authors: M.D.A. Nery, M.A.O. Alves, H.D. Aquino, E.A. Nery, L.B.M. Bezerra, R.T.M. Ribeiro and H.S.A. Monteiro
Cytogenetic studies of Philodryas nattereri and Philodryas olfersii revealed a diploid chromosome number 2n = 36 for both species (3 metacentrics, 4 submetacentrics, and 10 acrocentrics, with a fundamental number of 51 and 52, respectively). The results obtained are novel and similar to those previously described for species belonging to the Dipsadidae fa.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.11.3
- DOI:
- 10.4238/2015.June.11.3
Ring chromosome instability evaluation in six patients with autosomal rings
Authors: C.P. Sodr�?©, R.S. Guilherme, V.F.A. Meloni, D. Brunoni, Y. Juliano, J.A.D. Andrade, S.I.N. Belangero, D.M. Christofolini, L.D. Kulikowski and M.I. Melaragno
Ring chromosomes are often associated with abnormal phenotypes due to loss of genomic material and also because of ring instability at mitosis after sister chromatid exchange events. We investigated ring chromosome instability in six patients with ring chromosomes 4, 14, 15, and 18 by examining 48- and 72-h lymphocyte cultures.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr707
- DOI:
- 10.4238/vol9-1gmr707
Association between male infertility and androgen receptor mutations in Brazilian patients
Authors: C.O.A. Melo, A.R. Danin, D.M. Silva, J.A. Tacon, K.K.V.O. Moura, E.O.A. Costa and A.D. da Cruz
The androgen receptor is encoded by a single-copy gene located in the long arm of the X chromosome (Xq11-12); it consists of eight exons and encodes an intracellular transcription factor that belongs to the steroid/nuclear receptor superfamily. Disturbances in the function of the androgen receptor can lead to several forms of .. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr661
- DOI:
- 10.4238/vol9-1gmr661
Psychological characteristics of and counseling for carriers of structural chromosome abnormalities
Authors: H.L. Wang, B. Wu, K.M. Guo and R.H. Tian
Infertility as a psychological problem has gained increasing attention. Male partners among infertile couples have elevated levels of psychological distress, which could affect semen quality, result in hormonal abnormalities, and increase the occurrence of early miscarriage. Infertile women are more vulnerable to psychological.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028159
- DOI:
- 10.4238/gmr.15028159
Karyotypic evolution trends in Rhamdia quelen (Siluriformes, Heptapteridae) with considerations about the origin and differentiation of its supernumerary chromosomes
Authors: C. Garcia, C. Oliveira and L.F. Almeida-Toledo
Among catfish species of the genus Rhamdia reported for the Brazilian territory, R. quelen is the most widespread, being found in nearly all hydrographic basins of Brazil. Nowadays, R. quelen is a synonym for at least 47 other species in this genus, its taxonomic status still being controversial. The available cytogenetic repo.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr750
- DOI:
- 10.4238/vol9-1gmr750
Comparative study of the cytogenetic and molecular characteristics of Triatoma maculata and T. pseudomaculata (Heteroptera, Triatominae)
Authors: P.P. Mendon�?§a
Triatomines are hematophagous insects of great concern in public health because they are vectors of Trypanosoma cruzi, a protozoan that causes Chagas disease. Triatomines are also of great genetic interest, because they possess holocentric chromosomes and undergo an unusual form of meiosis with post-reductional segregation of .. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1TA029
- DOI:
- 10.4238/vol9-1TA029
Karyological features of wild and cultivated forms of myrtle (Myrtus communis, Myrtaceae)
Authors: S. Ser�?§e, E. Ekbi�?§, J. Suda, K. G�?¼nd�?¼z and Y. Kiyga
Myrtle is an evergreen shrub or small tree widespread throughout the Mediterranean region. In Turkey, both cultivated and wild forms, differing in plant and fruit size and fruit composition, can be found. These differences may have resulted from the domestication of the cultivated form over a long period of time. We investigat.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr748
- DOI:
- 10.4238/vol9-1gmr748
Assessment of clinical scoring systems for the diagnosis of Williams-Beuren syndrome
Authors: D.E.S. Leme, D.H. Souza, G. Mercado, E. Pastene, A. Dias and D. Moretti-Ferreira
Williams-Beuren syndrome (WBS) is a genetic disorder characterized by physical and intellectual developmental delay, associated with congenital heart disease and facial dysmorphism. WBS is caused by a microdeletion on chromosome 7 (7q11.23), which encompasses the elastin (ELN) gene and about 27 other genes. The gold standard for WBS laboratory diagnosis i.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.4.7
- DOI:
- 10.4238/2013.September.4.7