Chromosome
Meiotic pairing of B chromosomes, multiple sexual system, and Robertsonian fusion in the red brocket deer Mazama americana (Mammalia, Cervidae)
Authors: C.I. Aquino, V.V. Abril and J.M.B. Duarte
Deer species of the genus Mazama show significant inter- and intraspecific chromosomal variation due to the occurrence of rearrangements and B chromosomes. Given that carriers of aneuploidies and structural rearrangements often show anomalous chromosome pairings, we here performed a synaptonemal complex analysis to study chromosome pairing behavior in a r.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.13.1
- DOI:
- 10.4238/2013.September.13.1
Chromosomal characteristics of a Brazilian whip spider (Amblypygi) and evolutionary relationships with other arachnid orders
Authors: E. Paula-Neto, D. Araujo, L.S. Carvalho, D.M. Cella and M.C. Schneider
We analyzed mitotic and meiotic cells of a Brazilian amblypygid, Heterophrynus longicornis, using conventional and molecular cytogenetic techniques (Giemsa staining, C-banding, Ag-NOR, and FISH with rDNA probe). This is the first study that focuses solely on amblypygid chromosomes; it was undertaken to add data on cytogenetic knowledge of this group and c.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.19.3
- DOI:
- 10.4238/2013.September.19.3
Description of the pre-reductional sex chromosome during male meiosis of Pachylis laticornis (Heteroptera: Coreidae)
Authors: C.A. Banho, K.C.C. Alevi, L.L.V. Pereira, T.S. Souza-Firmino and M.M. Itoyama
In Heteroptera, the division of sex chromosomes is well defined as post-reductional for most of species, i.e., the first meiotic division is equational and the second is reductional. However, in some species pre-reductional division has been observed, whereby the first meiotic division is reductional and the second is equation.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027592
- DOI:
- 10.4238/gmr.15027592
Varicocele and male infertility in Northeast China: Y chromosome microdeletion as an underlying cause
Authors: R.L. Dai,Y. Hou,F.B. Li, J.M. Yue,Q. Xi and R.Z. Liu
The prevalence of Y chromosome microdeletions among azoospermic, severe oligozoospermic, moderate oligozoospermic, and mild oligozoospermic patients with varicocele-related and idiopathic infertility shows conflicting data in Asian countries. We aimed to detect this frequency in Northeast China, and investigated spermatogenic defects whether associated wi.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.12.13
- DOI:
- 10.4238/2015.June.12.13
NDC80 promotes proliferation and metastasis of colon cancer cells
Authors: X.K. Xing, H.Y. Wu, H.L. Chen and H.G. Feng
Chromosome instability is a common feature of tumor cells, and may be an important mechanism in tumor formation. Nuclear division cycle 80 (NDC80) is closely associated with the stability of chromosomes. Therefore, we investigated the relationship between NDC80 and development of colon cancer using a range of methods. Western .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028312
- DOI:
- 10.4238/gmr.15028312
Dynamics of chromosomal evolution in the genus Hypsiboas (Anura: Hylidae)
Authors: M.A. Carvalho, M.T. Rodrigues, S. Siqueira and C. Garcia
Hylidae is one of the most species-rich families of anurans, and 40% of representatives in this group occur in Brazil. In spite of such remarkable diversity, little is known about this family and its taxonomical and systematic features. Most hylids have 2n = 24, even though most of the cytogenetic data are mainly obtained base.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.26.21
- DOI:
- 10.4238/2014.September.26.21
Smallest critical region for microcephaly in a patient with mosaic ring chromosome 13
Authors: P.-H. Su, C.-P. Chen, Y.-N. Su, S.-J. Chen, L.-L. Lin and J.-Y. Chen
A ring chromosome 13 or r(13) exhibits breakage and reunion at breakage points on the long and short arms of chromosome 13, with deletions of the chromosomal segments distal to the breakage points. The r(13) chromosome accounts for approximately 20% of ring chromosomes compatible with life. We describe a female patient with mental retardation, growth reta.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.25.2
- DOI:
- 10.4238/2013.April.25.2
Construction and characterization of a bacterial artificial chromosome library for the allotetraploid Gossypium tomentosum
Authors: F. Liu, Y.H. Wang, H.Y. Gao, C.Y. Wang, Z.L. Zhou, X.Y. Cai, X.X. Wang, Z.S. Zhang and K.B. Wang
Gossypium tomentosum is a wild allotetraploid species with the (AD)5 genome. It is characterized by many useful traits including finer fiber fineness, drought tolerance, and Fusarium and Verticillium resistance. We constructed the first bacterial artificial chromosome library for Gossypium tomentosum. With high quality and broad coverage, this library inc.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.15.3
- DOI:
- 10.4238/2015.December.15.3
Additional chromosomal abnormalities in core-binding factor acute myeloid leukemia
Authors: H.H. Hsiao, Y.C. Liu, H.C. Wang, Y.F. Tsai, C.H. Wu, S.F. Cho, J.F. Hsu, C.T. Huang, S.Y. Hsiao, C.P. Lee, C.S. Chang, S.F. Lin and T.C. Liu
Despite sharing a similar genetic abnormality, patients with core binding factor acute myeloid leukemia (CBF-AML), which is characterized by the presence of t(8;21) or inv(16)/t(16;16), show heterogeneous survival. Other molecular or cytogenetic factors are supposed to have an impact on the prognosis. We enrolled 24 CBF-AML patients to determine the impac.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.3
- DOI:
- 10.4238/2015.December.16.3
Correlation between Y chromosome microdeletion and male infertility
Authors: X.G. Liu, H.Y. Hu, Y.H. Guo and Y.P. Sun
Dyszoospermia due to genetic factors is the leading cause of male infertility. To explore the correlation between azoospermia factor (AZF) microdeletion of the Y chromosome and male infertility, we evaluated AZF microdeletion on the long arm of the Y chromosome in 166 infertile males and 50 fertile males using multiplex polyme.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028426
- DOI:
- 10.4238/gmr.15028426