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Chromosome

Human Genetics   Research Article

Analysis of BCR/ABL transcripts in healthy individuals

Authors: J.A. Boquett1, J.R.P. Alves2 and C.E.C. de Oliveira3

The chimeric oncogene BCR/ABL, which is the product of reciprocal translocation between chromosomes 9 and 22, is a known molecular marker of chronic myeloid leukemia (CML), and is related to the major factors involved in leukemogenesis. Some previous studies have also reported the presence of this oncogene in peripheral blood cells of healthy individuals... Read More»

Genet. Mol. Res. 12(4):
2013.October.24.8
DOI:
10.4238/2013.October.24.8
Plant Genetics   Research Article

Different timing and spatial separation of parental chromosomes in intergeneric somatic hybrids between Brassica napus and Orychophragmus violaceus

Authors: L. Ding, Z.G. Zhao, X.H. Ge and Z.Y. Li

Experimental and newly formed hybrids and polyploids generated by wide crosses usually show varying degrees of cytological instability. The spatial separation of parental genomes and uniparental chromosome elimination in hybrid cells has been reported in many hybrids from plants and animals. Herein, the behavior of parental ge.. Read More»

Genet. Mol. Res. 13(2):
2014.April.8.3
DOI:
10.4238/2014.April.8.3
Human Genetics   Research Article

Infertility caused by male partners with genetic defects in Sichuan Province of China

Authors: Q. Quan, T.J. Li, X.P. Ding, J. Wei, L.X. Li and L. Fu

The purpose of this study was to detect chromosomal aberrations and azoospermia factor (AZF) microdeletions in male patients with reproductive problems and to summarize related clinical features to provide reliable information for evaluating prenatal and preimplantation diagnoses. A large cohort of 5083 men with various phenotypes of male infertility was .. Read More»

Genet. Mol. Res. 12(4):
2013.December.11.2
DOI:
10.4238/2013.December.11.2
Human Genetics   Research Article

Cytogenetic studies on meiotic chromosome behaviors in sterile Oriental x Trumpet lily

Authors: J.R. Luo, J.M. Van Tuyl, P. Arens and L.X. Niu

In order to determine the reasons for pollen sterility in lily hybrids, four diploid sterile Oriental x Trumpet (OT) lily cultivars (‘Nymph’, ‘Gluhwein’, ‘Yelloween’, and ‘Shocking’) were used to investigate the meiotic chromosome behaviors in pollen mother cells (PMCs), using genomic in situ hybridization a.. Read More»

Genet. Mol. Res. 12(4):
2013.December.13.1
DOI:
10.4238/2013.December.13.1
Human Genetics   Research Article

Case report of isochromosome 17q in acute myeloid leukemia with myelodysplasia-related changes after treatment with a hypomethylating agent

Authors: J.C. Sousa, R.T. Germano, C.C.M. Castro, S.M.M. Magalhaes and R.F. Pinheiro

Isochromosome 17q is a relatively common karyotypic abnormality in medulloblastoma, gastric, bladder, and breast cancers. In myeloid disorders, it is observed during disease progression and evolution to acute myeloid leukemia in Philadelphia-positive chronic myeloid leukemia. It has been reported in rare cases of myelodysplast.. Read More»

Genet. Mol. Res. 11(3):
2012.August.6.8
DOI:
10.4238/2012.August.6.8
Human Genetics   Research Article

Sex chromosome differentiation in Belostoma (Insecta: Heteroptera: Belostomatidae)

Authors: V.B. Bardella, A.L. Dias, L. Giuliano-Caetano, J.R.I. Ribeiro and R. Da Rosa

Belostoma, a genus of the family Belostomatidae, includes species of great ecological importance as biocontrol agents. Few species of these species have been the subject of cytogenetic analyses. Karyotypic evolution in this genus involves agmatoploidy and simploidy; there are also different sex chromosome systems. We examined two Belostoma species (B. dil.. Read More»

Genet. Mol. Res. 11(3):
2012.May.21.2
DOI:
10.4238/2012.May.21.2
Animal Genetics   Research Article

Physical mapping of 18S and 5S rDNA loci and histone H3 gene in grasshopper species of the subfamily Gomphocerinae (Acrididae)

Authors: L.C. Silva-Neto, A.C.S. Bernardino, V. Loreto and R.C. Moura

In this study, fluorescence in situ hybridization (FISH) analysis was used to determine and compare the numbers and chromosomal locations of two multigene families (rDNA and histone H3) in four Neotropical species of gomphocerine grasshoppers. FISH using the 18S rDNA probe identified a single site on the S9 chromosome.. Read More»

Genet. Mol. Res. 14(4):
2015.November.24.8
DOI:
10.4238/2015.November.24.8
Medical Genetics   Research Article

Structure and polymorphism of novel X-chromosome short tandem repeat loci in a Chinese Han population

Authors: Y.S. Zhu, H. Wu and J.H. Lai

Recently, 5 novel X-chromosome short tandem repeat (X-STR) loci with high degrees of polymorphism were examined. In this study, we investigated the genetic distribution of these loci in a Chinese Han population. The 5 X-STR loci were successfully examined by polyacrylamide gel electrophoresis in a total of 200 unrelated Shaanx.. Read More»

Genet. Mol. Res. 14(4):
2015.November.24.12
DOI:
10.4238/2015.November.24.12
Animal Genetics   Research Article

Comparative cytogenetics of spiny rats of the genus Proechimys (Rodentia, Echimyidae) from the Amazon region

Authors: E.S. Eler, M.N.F. da Silva, C.E.F. Silva and E. Feldberg

We made a comparative analysis of the cytogenetics of spiny rat species of the genus Proechimys collected from several sites of the Madeira River basin (Amazonas State, Brazil) and Jari River valley (Pará State, Brazil). Individuals were assigned to three groups based on diploid and fundamental numbers: 2n = 28, FN = 46.. Read More»

Genet. Mol. Res. 11(2):
2012.April.3.5
DOI:
10.4238/2012.April.3.5
Plant Genetics   Research Article

PpPIF-1: first isolated full-length PIF-like element from the bamboo Phyllostachys pubescens

Authors: M.B. Zhou, X.M. Liu and D.Q. Tang

PIF-like elements are the first-described members of a recently discovered and widespread superfamily of DNA transposons, named PIF/Harbinger. Complete and partial PIF-like elements have been isolated from hundreds of plant species. Previously, we identified 139 partial PIF-like transposases in the Bambusoideae, of which three.. Read More»

Genet. Mol. Res. 11(2):
2012.April.3.3
DOI:
10.4238/2012.April.3.3