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Dna

Cytogenomics   Research Article

Cytogenetic and random amplified polymorphic DNA analysis of Leptodactylus species from rural and urban environments (Anura, Amphibia)

Authors: M.P. Arruda and E. Morielle-Versute

Cytogenetic and random amplified polymorphic DNA analyses carried out in the species Leptodactylus podicipinus, L. ocellatus, L. labyrinthicus, and L. fuscus from rural and urban habitats of the northwest region of São Paulo State, Brazil, showed that the karyotypes (2n = 22), constitutive heterochromatin distribution and nucleolus organizer region.. Read More»

Genet. Mol. Res. 7(1):
vol7-1gmr402
DOI:
10.4238/vol7-1gmr402
Plant Genetics   Research Article

Selection of DNA barcoding loci and phylogenetic study of a medicinal and endemic plant, Plectranthus asirensis J.R.I. Wood from Saudi Arabia

Authors: F. Al-Qurainy, S. Khan, M. Nadeem, M. Tarroum and A. Al-Ameri

Genuine medicinal plant materials are very important for potential crude drug production, which can be used to cure many human diseases. DNA barcoding of medicinal plants is an effective way to identify adulterated or contaminated market materials, but it can be quite challenging to generate barcodes and analyze the data to de.. Read More»

Genet. Mol. Res. 13(3):
2014.August.7.31
DOI:
10.4238/2014.August.7.31
Microbial Genetics   Short communication

DNA repair by polymerase �´ in Saccharomyces cerevisiae is not controlled by the proliferating cell nuclear antigen-like Rad17/Mec3/Ddc1 complex

Authors: J.M. Cardone, M. Brendel and J.A.P. Henriques

DNA damage activates several mechanisms such as DNA repair and cell cycle checkpoints. The Saccharomyces cerevisiae heterotrimeric checkpoint clamp consisting of the Rad17, Mec3 and Ddc1 subunits is an early response factor to DNA damage and activates checkpoints. This complex is structurally similar to the proliferating cell nuclear antigen (PCNA), which.. Read More»

Genet. Mol. Res. 7(1):
vol7-1gmr405
DOI:
10.4238/vol7-1gmr405
Human Genetics   Research Article

Gene expression analysis of demineralized bone matrix-induced osteogenesis in human periosteal cells using cDNA array technology

Authors: S. Honsawek, P. Bumrungpanichthaworn, T. Thitiset and L. Wolfinbarger Jr.

Demineralized bone matrix (DBM) has been widely investigated as a biomaterial to promote new bone formation and is utilized clinically for bone repair and regeneration. We investigated gene expression patterns of osteogenic differentiation in human periosteal (HPO) cells cultured with demineralized bone matrix, using cDNA arra.. Read More»

Genet. Mol. Res. 10(3):
vol10-3gmr1329
DOI:
10.4238/vol10-3gmr1329
Microbial Genetics   Research Article

Molecular variability in Brycon cf. pesu M�¼ller and Troschel, 1845 (Characiformes: Characidae) from the Araguaia-Tocantins basin

Authors: R.S. Panarari-Antunes, A.J. Prioli, S.M.A.P. Prioli, H.F. J�ºlio Jr. C.S. Agostinho and L.M. Prioli

Brycon pesu is a small-sized fish distributed throughout the Amazon and Orinoco Basins and other coastal basins of northeastern South America. Brycon cf. pesu specimens from the Araguaia-Tocantins Basin are currently separated into two morphotypes, Brycon sp1 and Brycon sp2, owing to different coloration of their anal fin. Brycon sp2 has a reddish margin .. Read More»

Genet. Mol. Res. 7(1):
vol7-1gmr365
DOI:
10.4238/vol7-1gmr365
Medical Genetics   Research Article

ABO genotyping in leukemia patients reveals new ABO variant alleles

Authors: M.C.Z. Novaretti, A.E. Domingues, R. Manhani, E.M. Pinto, P.E. Dorlhiac-Llacer and D.A.F. Chamone

The ABO blood group is the most important blood group system in transfusion medicine and organ transplantation. To date, more than 160 ABO alleles have been identified by molecular investigation. Almost all ABO genotyping studies have been performed in blood donors and families and for investigation of ABO subgroups detected serologically. The aim of the .. Read More»

Genet. Mol. Res. 7(1):
vol7-1gmr401
DOI:
10.4238/vol7-1gmr401
Microbial Genetics   Research Article

Identification of actinomycete communities in Antarctic soil from Barrientos Island using PCR-denaturing gradient gel electrophoresis

Authors: L. Learn-Han, C. Yoke-Kqueen, M.S. Shiran, C.M.W. Vui-Ling, A.M. Nurul-Syakima, R. Son and H.M. Andrade

The diversity of specific bacteria taxa, such as the actinomycetes, has not been reported from the Antarctic island of Barrientos. The diversity of actinomycetes was estimated with two different strategies that use PCR-denaturing gradient gel electrophoresis. First, a PCR was applied, using a group-specific primer that allows .. Read More»

Genet. Mol. Res. 11(1):
http://dx.doi.org/2012.February.8.3
DOI:
http://dx.doi.org/10.4238/2012.February.8.3
Bioinformatics   Review Article

Mutual information content of homologous DNA sequences

Authors: Helena Cristina G. Leit�£o, Luciana S. Pess�´a and Jorge Stolfi

The necessary information to reproduce and keep an organism is codified in acid nucleic molecules. Deepening the knowledge about how the information is stored in these bio-sequences can lead to more efficient methods of comparing genomic sequences. In the present study, we analyzed the quantity of information contained in a DN.. Read More»

Genet. Mol. Res. 4(3):
Human Genetics   Research Article

The mutation G298A�Ala100Thr on the coding sequence of the Duffy antigen/chemokine receptor gene in non-caucasian Brazilians

Authors: Angela Cristina Estalote, Rodrigo Proto-Siqueira, Wilson Ara�ºjo Da Silva Jr., Marco Antonio Zago and Marcos Palatnik

Ala100Thr has been suggested to be a Caucasian genetic marker on the FY*B allele. As the Brazilian population has arisen from miscegenation among Portuguese, Africans, and Indians, this mutation could possibly be found in Euro- and Afro-Brazilians, or in Brazilian Indians. Fifty-three related individuals and a random sample of.. Read More»

Genet. Mol. Res. 4(2):
Plant Genetics   Research Article

Allele frequencies for 12 autosomal short tandem repeat loci in two bolivian populations

Authors: L. Cifuentes, H. Jorquera, M. Acu�±a, J. Ord�³�±ez and A.L. Sierra

Two hundred and sixty unrelated subjects who asked for paternity testing at two Bolivian Laboratories in La Paz and Santa Cruz were studied. The loci D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, TH01, TPOX, and CSF1PO were typed from blood samples, amplifying DNA by polymerase chain reactions and electr.. Read More»

Genet. Mol. Res. 7(1):
vol7-1gmr368
DOI:
10.4238/vol7-1gmr368