Expression
Molecular characterization, expression, and functional analysis of chicken TRAF6
Authors: J. Jin, J.S. Ran, C.W. Yang, X.S. Jiang, Y.G. Zhou, Z.Q. Feng, Y. Wang, D. Lan, P. Ren and Y.P. Liu
Tumor necrosis factor receptor-associated factor 6 (TRAF6) is a crucial adaptor molecule of the interleukin-1 receptor/Toll-like receptor (IL-1/TLR) superfamily, which can trigger downstream signaling cascades involved in innate immunity. The function of TRAF6 has been clarified in mammals but is poorly understood in chicken. .. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019138
- DOI:
- 10.4238/gmr16019138
Effects of feeding conditions on gene expression in chicken breast muscle
Authors: G.L. Gao, C. Wang, X.Z. Zhao, H.W. Wang, Q. Li, J. Li, K.S. Zhang, H. Zhong and Q.G. Wang
Chicken meat quality is becoming increasingly important among breeders and consumers. To understand the effect of feeding conditions on chicken meat quality, we investigated the profiles of genes expressed in chicken breast muscle. Using RNA sequencing, we identified 336, 321, and 387 differentially expressed genes among Cheng.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019119
- DOI:
- 10.4238/gmr16019119
Identification and characterization of TGF�²-dependent and -independent cis-regulatory modules in the C4ST-1/CHST11 locus
Authors: C.M. Willis, J.L. Wrana and M. Kl�¼ppel
Chondroitin-4-sulfotransferase-1(C4ST-1)/carbohydrate sulfotransferase 11 (CHST11) is a Golgi-bound enzyme involved in the biosynthesis of the glycosaminoglycan chondroitin sulfate. The sulfation pattern of chondroitin is tightly regulated during development, injury and disease, with the temporal and spatial expressi.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr673
- DOI:
- 10.4238/vol8-4gmr673
Correlation-based linear discriminant classification for gene expression data
Authors: M. Pan and J. Zhang
Microarray gene expression technology provides a systematic approach to patient classification. However, microarray data pose a great computational challenge owing to their large dimensionality, small sample sizes, and potential correlations among genes. A recent study has shown that gene-gene correlations have a positive effe.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019357
- DOI:
- 10.4238/gmr16019357
Construction and transformation of expression vector containing Panax japonicus SS gene
Authors: L. Zhang and T.T. Wang
Panax japonicus C.A. Meyer, a perennial herb belonging to the Araliaceae ginseng genus, is one of the seven rare and endangered Chinese medical herbs. By cloning the SS segment, the expression vectors pCXSN-PjSS and pCXSN-antiPjSS were constructed and introduced into Agrobactria LBA4404, which is used for engineering bacteria... Read More»
- Genet. Mol. Res. 16(1):
- gmr16019341
- DOI:
- 10.4238/gmr16019341
Characterization of chicken natural resistance-associated macrophage protein encoding genes (Nramp1 and Nramp2) and association with salmonellosis resistance
Authors: X.M. He M.X. Fang Z.T. Zhang Y.S. Hu X.Z. Jia D.L. He S.D. Liang Q.H. Nie X.Q. Zhang
Natural resistance-associated macrophage protein 1 and 2 encoding genes (Nramp1 and Nramp2) are related to many diseases. We cloned the cDNA of chicken Nramp1 and Nramp2 genes, characterized their expression and polymorphisms, and investigated the association of some SNPs with resistance to salmonellosis. The Nramp1 cDNA was 1746 bp long and the Nramp2 cD.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.30.5
- DOI:
- 10.4238/2013.January.30.5
Involvement of ERK1/2 signaling in proliferation of eight liver cell types during hepatic regeneration in rats
Authors: X.G. Chen C.S. Xu Y.M. Liu
It has been well established that ERK1/2 signaling, often subdivided into nine types of pathways, can regulate the hepatocyte proliferative response during liver regeneration. However, the effect of ERK1/2 signaling on the proliferation of other hepatic cell types remains unclear. We isolated and purified 8 liver cell types at 10 time points after 2/3 hep.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.March.11.14
- DOI:
- 10.4238/2013.March.11.14
Cloning and characterization of SPL-family genes in the peanut (Arachis hypogaea L.)
Authors: M. Li1*, S.Z. Zhao1*, C.Z. Zhao1, Y. Zhang1, H. Xia1, J. Lopez-Baltazar2, S.B. Wan1 and X.J. Wang1
SQUAMOSA promoter-binding protein-like (SPL) proteins play crucial roles in plant growth, development, and responses to environmental stressors. The peanut (Arachis hypogaea L.) is a globally important oil crop. In this study, we cloned the full-length cDNA of 15 SPLs in the peanut by transcriptome sequencing and rapid amplification of cDNA ends, and anal.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017344
- DOI:
- 10.4238/gmr.15017344
Cloning and characterization of defense-related genes from Populus szechuanica infected with rust fungus Melampsora larici-populina
Authors: Z.J. Chen1,2, Z.M. Cao1, Z.D. Yu1 and D. Yu1
Characterization of defense-related genes is critical for breeding disease-resistant poplar varieties and for better management and control of leaf rust disease. In the present study, full-length cDNAs of five Populus szechuanica defense-related (PsDR) genes, pathogen-related protein 1 (PsPR1), β-1,3-glucanase (PsGns), thaumatin-like protein 1 (PsTLP.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017314
- DOI:
- 10.4238/gmr.15017314
Abundance and diversity of resistance genes in the sugarcane transcriptome revealed by in silico analysis
Authors: A.C. Wanderley-Nogueira, N.M. Soares-Cavalcanti, D.A.L. Morais, L.C. Belarmino, A. Barbosa-Silva and A.M. Benko-Iseppon
Resistance genes (R-genes) are responsible for the first interaction of the plant with pathogens being responsible for the activation (or not) of the defense response. Despite their importance and abundance, no tools for their automatic annotation are available yet. The present study analyzed R-genes in the sugarcane expressed.. Read More»
- Genet. Mol. Res. 6(4):