Expression
Age-related pyrethroid resistance is not a function of P450 gene expression in the major African malaria vector, Anopheles funestus (Diptera: Culicidae)
Authors: R.N. Christian, T.S. Matambo, B.L. Spillings, B.D. Brooke, M. Coetzee and L.L. Koekemoer
Anopheles funestus is a major vector of malaria in most of the African region. Resistance to pyrethroid and carbamate insecticides has been recorded in populations of this species in South Africa and Mozambique. The P450 gene, CYP6P9, has been shown to be highly transcribed in a permethrin (pyrethroid)-resistant laboratory str.. Read More»
- Genet. Mol. Res. 10(4):
- /2011.December.21.4
- DOI:
- /10.4238/2011.December.21.4
Proteomic and gene expression analyses during bolting-related leaf color change in Brassica rapa
Authors: Y.W. Zhang, M.H. Guo, X.B. Tang, D. Jin and Z.Y. Fang
Bolting and flowering are key processes during the growth and development of Chinese cabbage (Brassica rapa L. ssp pekinensis). Understanding the molecular mechanisms underlying bolting and flowering is of significance for improving production of the vegetable. A leaf-color change from bright green to gray-green has been observed following differentiation.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038584
- DOI:
- 10.4238/gmr.15038584
EPSPS variability, gene expression, and enzymatic activity in glyphosate-resistant biotypes of Digitaria insularis
Authors: E. Galeano, A.A.M. Barroso, T.S. Vasconcelos, A. L�³pez-Rubio, A.J.P. Albrecht, R. Victoria Filho and H. Carrer
Weed resistance to herbicides is a natural phenomenon that exerts selection on individuals in a population. In Brazil, glyphosate resistance was recently detected in Digitaria insularis. The objective of this study was to elucidate mechanisms of weed resistance in this plant, including genetic variability, allelism, amino acid substitutions, gene expressi.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038730
- DOI:
- 10.4238/gmr.15038730
Porcine MAP3K5 analysis: molecular cloning, characterization, tissue expression pattern, and copy number variations associated with residual feed intake
Authors: L. Pu, L.C. Zhang, J.S. Zhang, X. Song, L.G. Wang, J. Liang, Y.B. Zhang, X. Liu, H. Yan, T. Zhang, J.W. Yue, N. Li, Q.Q. Wu and L.X. Wang
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5) is essential for apoptosis, proliferation, differentiation, and immune responses, and is a candidate marker for residual feed intake (RFI) in pig. We cloned the full-length cDNA sequence of porcine MAP3K5 by rapid-amplification of cDNA ends. The 5451-bp gene contains a 5'-untranslated region (UTR) .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15037998
- DOI:
- 10.4238/gmr.15037998
Protein-protein interaction network and mechanism analysis of hepatitis C
Authors: Y. Tang, Q. Tang, C. Dong, X. Li, Z. Zhang and F. An
We predicted potential genes and identified pathways associated with hepatitis C. The gene expression profiles of GSE40184 from blood samples and GSE38597 from liver biopsy samples were downloaded from the GEO database. Differentially expressed genes (DEGs) were recognized using the Limma Package. The Pearson correlation test was used to construct the co-.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.20.17
- DOI:
- 10.4238/2015.March.20.17
Correlation between sheep YAP1 temporal and spatial expression trends and MSTN and MyoG gene expression
Authors: X.Y. Lv, W. Sun, R. Su, D. Li, Q.Z. Wang, H.H. Musa, L. Chen, Y.F. Zhang and W.Z. Wu
The aim of the current study was to investigate the effects of Yes-associated protein 1 (YAP1) gene expression after birth on the development of muscle and the relationship between YAP1 and myostatin (MSTN) and myogenin (MyoG). Reverse transcription polymerase chain reaction was used to analyze the trends in YAP1, MSTN, and MyoG temporal and spatial expre.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.13.3
- DOI:
- http://dx.doi.org/10.4238/2015.April.13.3
Comprehensive identification and expression analysis of Hsp90s gene family in Solanum lycopersicum
Authors: W.S. Zai, L.X. Miao, Z.L. Xiong, H.L. Zhang, Y.R. Ma, Y.L. Li, Y.B. Chen and S.G. Ye
Heat shock protein 90 (Hsp90) is a protein produced by plants in response to adverse environmental stresses. In this study, we identified and analyzed Hsp90 gene family members using a bioinformatic method based on genomic data from tomato (Solanum lycopersicum L.). The results illustrated that tomato contains at least 7 Hsp90 genes distributed on 6 chrom.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.14.7
- DOI:
- 10.4238/2015.July.14.7
Differential gene expression of epigenetic modifying enzymes between Tibet pig and Yorkshire in high and low altitudes
Authors: D.M. Ban, B. Zhang, Z.X. Wang, H. Zhang and C.X. Wu
Epigenetic modifying enzymes play important roles in the adaptation to hypoxia, although no studies have examined their expression levels in Tibet pigs. The lung is an important functional organ in hypoxia adaptation. In this study, we examined the mRNA expression level of 5 enzymes in the lung of Tibet pigs using real-time polymerase chain reaction to de.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.13.6
- DOI:
- http://dx.doi.org/10.4238/2015.April.13.6
Meta-analysis of differentially expressed genes in autism based on gene expression data
Authors: L.F. Ning, Y.Q. Yu, E.T. GuoJi, C.G. Kou, Y.H. Wu, J.P. Shi,L.Z. Ai and Q. Yu
The purpose of this study was to identify differentially expressed (DE) genes and biological processes associated with changes in gene expression in autism. We performed a meta-analysis using new publicly available Gene Expression Omnibus (GEO) datasets of autism. We performed Gene Ontology (GO) enrichment analyses and pathway analysis using the Kyoto Enc.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.27.1
- DOI:
- 10.4238/2015.March.27.1
Molecular cloning and characterization of a subtilisin-like protease from Arabidopsis thaliana
Authors: D.H. Li, H. Xi, X.B. Yu and Y.P. Cai
The Arabidopsis thaliana genome encodes 56 subtilisin-like serine proteases (subtilases). In order to evaluate the protease activity of a previously uncharacterized subtilase, designated as AtSBT1.9, we cloned its full-length cDNA from A. thaliana seedlings. An AtSBT1.9 mature peptide coding sequence was inserted into the bacterial expression vector, pMAL.. Read More»
- Genet. Mol. Res. 14(4):
- 2015
- DOI:
- 10.4238/2015