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Expression

Medical Genetics   Research Article

Detecting the potential cancer association or metastasis by multi-omics data analysis

Authors: L. Hua, WY. Zheng, H. Xia and P. Zhou

Comprehensive multi-omics data analyses have become an important means for understanding cancer incidence and progression largely driven by the availability of high-throughput sequencing technologies for genomes, proteomes, and transcriptomes. However, how tumor cells from the site of origin of the cancer begin to grow in other sites of the body is very p.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038987
DOI:
10.4238/gmr.15038987
Human Genetics   Research Article

Defective eyelid leading edge cell migration in C57BL/6-corneal opacity mice with an â??eye open at birthâ? phenotype

Authors: L.C. Wu, C. Liu, M.R. Jiang ,Y.M. Jiang, Q.H. Wang, Z.Y. Lu, S.J. Wang, W.L. Yang and Y.X. Shao

Development of the eyelid requires coordination of the cellular processes involved in proliferation, cell size alteration, migration, and cell death. C57BL/6J-corneal opacity (B6-Co) mice are mutant mice generated by the administration of N-ethyl-N-nitrosourea (100 mg/kg). They exhibit the eyelids open at birth phenotype, abnormal round cell shape from ti.. Read More»

Genet. Mol. Res. 15(3):
gmr.15036741
DOI:
10.4238/gmr.15036741
Animal Genetics   Research Article

cDNA, genomic sequence cloning and overexpression of ribosomal protein gene L9 (rpL9) of the giant panda (Ailuropoda melanoleuca)

Authors: W.R. Hou, Y.L. Hou, G.F. Wu, Y. Song, X.L. Su, B. Sun and J. Li

The ribosomal protein L9 (RPL9), a component of the large subunit of the ribosome, has an unusual structure, comprising two compact globular domains connected by an α-helix; it interacts with 23 S rRNA. To obtain information about rpL9 of Ailuropoda melanoleuca (the giant panda) we designed primers based on the known mam.. Read More»

Genet. Mol. Res. 10(3):
vol10-3gmr1159
DOI:
10.4238/vol10-3gmr1159
Animal Genetics   Research Article

Temporal and spatial expression of Smads and their correlation with YAP1 expression in sheep

Authors: W. Gao, R. S, W. Sun, Q.Z. Wang, X.Y. Lv, J.J. Bao, J.R. Yu, L.H. Wang, H.H. Musa and L. Chen

The temporal and spatial patterns of Smad and Yes-associated protein 1 (YAP1) expression were investigated in skeletal muscle (gastrocnemius muscle and extensor digitorum longus) at different growth stages (2 days old, 2 and 6 months old) in Hu sheep. Smads were differentially expressed in sheep skeletal muscle, with high expression in the gastrocnemius m.. Read More»

Genet. Mol. Res. 15(3):
gmr.15037715
DOI:
10.4238/gmr.15037715
Human Genetics   Research Article

Gene expression profiling analysis of 5-hydroxytryptamine signaling pathway in rat regenerating liver and different types of liver cells

Authors: C.F. Chang, J. Yang, W.M. Zhao, Y. Li, P.J. Guo, M.H. Li, Y. Zhou and C.S. Xu

We examined the gene expression profiles of the 5-hydroxytryptamine signaling pathway in the regenerating liver and 8 types of liver cells during rat liver regeneration, and explored expression differences in 5-hydroxytryptamine signaling pathway genes at the level of tissues and cells, as well as the role of the pathway on liver regeneration. Eight types.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.15.4
DOI:
http://dx.doi.org/10.4238/2015.April.15.4
Microbial Genetics   Research Article

Two chitin metabolic enzyme genes from Hyriopsis cumingii: cloning, characterization, and potential functions

Authors: G.-L. Wang B. Xu Z.-Y. Bai J.-L. Li

Chitin, the second most important natural polymer in the world, and its N-deacetylated derivative chitosan are found in a wide variety of organisms. These versatile biopolymers are associated with a broad range of biological functions. This article is the first to report the potential functions of 2 chitin metabolic enzyme gen.. Read More»

Genet. Mol. Res. 11(4):
2012.October.15.4
DOI:
10.4238/2012.October.15.4
Plant Genetics   Research Article

Expression of drought tolerance genes in tropical upland rice cultivars (Oryza sativa)

Authors: R.D.D. Silveira, F.R.M. Abreu, S. Mamidi, P.E. McClean, R.P. Vianello, A.C. Lanna, N.P. Carneiro and C. Brondani

Gene expression related to drought response in the leaf tissues of two Brazilian upland cultivars, the drought-tolerant Douradão and the drought-sensitive Primavera, was analyzed. RNA-seq identified 27,618 transcripts in the Douradão cultivar, with 24,090 (87.2%) homologous to the rice database, and 27,221 transcripts in the Primavera cultiv.. Read More»

Genet. Mol. Res. 14(3):
2015.July.27.6
DOI:
10.4238/2015.July.27.6
Human Genetics   Research Article

Transforming growth factor beta-1 expression in macrophages of human chronic periapical diseases

Authors: Z.-Z. Liang, J. Li, S.-G. Huang

The objective of this study was to observe the distribution of macrophages (MPs) expressing transforming growth factor beta-1 (TGF-β1) in tissue samples from patients with different human chronic periapical diseases. In this study, samples were collected from 75 volunteers, who were divided into three groups according to .. Read More»

Genet. Mol. Res. 16(1):
gmr16019329
DOI:
10.4238/gmr16019329
Human Genetics   Research Article

Analysis of SLC11A1 gene expression in healthy water buffalo (Bubalus bubalis) blood cells using qPCR

Authors: A. Cris? , G. De Matteis, M.C. Scat?  and B. Moioli

SLC11A1 (solute carrier family 11 member 1 protein) gene influences the initial phase of bacterial cellular infections through macrophage activation. Recent literature on buffalo has attempted to associate the genotype of the polymorphic microsatellite located in the 3ê??untranslated region (3ê??UTR) of the gene, with either susceptibility to brucel.. Read More»

Genet. Mol. Res. 12(4):
201
DOI:
10.4238/201
Plant Genetics   Research Article

Identification of genes related to floral organ development in pak choi by expression profiling

Authors: H.X. Song, A.M. Ping, M.X. Sun, X.H. Qi, M.Y. Gao, X.Y. Xu,Z.J. Zhu, M.L. Li and L.P. Hou

Pak choi is a highly nutritious vegetable that is widely grown in China, Southeast Asia, and other parts of the world. Because it reproduces by seed, it is very important to understand the mechanism of floral organ development. Therefore, using the Chinese cabbage genome as a reference, this study analyzed the expression profi.. Read More»

Genet. Mol. Res. 16(1):
gmr16019233
DOI:
10.4238/gmr16019233