Expression
Identification of COL6A1 as a differentially expressed gene in human astrocytomas
Authors: A. Fujita, J.R. Sato, F. Festa, L.R. Gomes, S.M. Oba-Shinjo,S.K.N. Marie, C.E. Ferreira and M.C. Sogayar
Diffuse infiltrating gliomas are the most common tumors of the central nervous system. Gliomas are classified by the WHO according to their histopathological and clinical characteristics into four classes: grade I (pilocytic astrocytoma), grade II (diffuse astrocytoma), grade III (anaplastic astrocytoma), and grade IV (gliobla.. Read More»
- Genet. Mol. Res. 7(2):
- vol7-2gmr432
- DOI:
- 10.4238/vol7-2gmr432
Molecular characterization and upregulation of cytosolic manganese superoxide dismutase by imidazole derivative KK-42 in Macrobrachium nipponense
Authors: W.F. Wang, L.M. Mu, X.S. Wu, H. Yang and Q.J. Ning
Imidazole derivative KK-42 is a well-known regulator of insect growth. KK-42 pretreatment has been shown to promote the survival of Macrobrachium nipponense infected with Aeromonas hydrophila, possibly via activation of superoxide dismutase (SOD). In this study, the cytMnSOD gene was cloned from the hepatopancreas of M. nippon.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038484
- DOI:
- 10.4238/gmr.15038484
Identification and abundance of miRNA in chicken hypothalamus tissue determined by Solexa sequencing
Authors: G.R. Sun, M. Li, G.X. Li, Y.D. Tian, R.L. Han and X.T. Kang
We used Solexa sequencing technology to identify and determine the abundance of miRNAs and compared the characteristics and expression patterns of miRNA of 1-day-old and 36-week-old chicken hypothalamuses. We obtained 17,825,753 and 10,928,745 high-quality reads from 36-week-old and 1-day-old chickens, respectively. Three hund.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.October.2.2
- DOI:
- 10.4238/2012.October.2.2
Cloning of an anthocyanidin synthase gene homolog from blackcurrant (Ribes nigrum L.) and its expression at different fruit stages
Authors: X.-G. Li, J. Wang and Z.-Y. Yu
Anthocyanidin synthase (ANS), a 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase, catalyzes the penultimate step in anthocyanin biosynthesis, from leucoanthocyanidins to anthocyanidins, the first colored compound in the anthocyanin pathway. In this study, a full-length, 1427-bp long cDNA named RnANS1, which is homologous to the anthocyanidin synthase g.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.31.2
- DOI:
- http://dx.doi.org/10.4238/2015.March.31.2
Overexpression of the A-FABP gene facilitates intermuscular fat deposition in transgenic mice
Authors: Z.W. Liu, H.L. Fan, X.F. Liu, X.B. Ding, T. Wang, G.N. Sui,G.P. Li and H. Guo
Adipocyte fatty acid-binding protein (A-FABP), the most abundant FABP in adipocytes, controls fatty acid uptake, transport, and metabolism in fat cells. We constructed a transgenic mice model that overexpressed the cattle A-FABP gene to investigate the relationship between A-FABP expression and intermuscular fat deposition. There was no significant differ.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.31.4
- DOI:
- http://dx.doi.org/10.4238/2015.March.31.4
Molecular cloning and expression pattern of oriental river prawn (Macrobrachium nipponense) nitric oxide synthase
Authors: N.M.A. Rahman, H.T. Fu, S.M. Sun, H. Qiao, S. Jin1,, H.K. Bai, W.Y. Zhang, G.X. Liang, Y.S. Gong, Y.W. Xiong and Y. Wu
Nitric oxide synthase (NOS) produces nitric oxide (NO) by catalyzing the conversion of l-arginine to l-citrulline, with the concomitant oxidation of nicotinamide adenine dinucleotide phosphate. Recently, various studies have verified the importance of NOS invertebrates and invertebrates. However, the NOS gene family in the ori.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038541
- DOI:
- 10.4238/gmr.15038541
Allele- and parent-of-origin-specific effects on expression of the KCNJ11 gene: A candidate for meat tenderness in cattle
Authors: M.M. de Souza, S.C.M. Niciura, P.C. Tizioto, A.M.G. Ibelli G. Gasparin, M.I.P. Rocha, F.A. Bressani, W. Malag�³-Jr, W.J.S. Diniz, P.S.N. de Oliveira, A.O. Lima1, M.A. Mudadu, W. Barioni Junior,L.L. Coutinho and L.C.A. Regitano
In contrast to the Mendelian inheritance model, parental alleles can contribute unequally to gene expression, which may result in phenotypic variance among individuals and bias in the predicted additive effect of molecular markers associated with production traits. Given the need to understand the effects of allelic variation .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038549
- DOI:
- 10.4238/gmr.15038549
Module function and two-way clustering analysis of Epstein-Barr virus-related nasopharyngeal cancer
Authors: F. Chen, J. Liu, M. Fan, X.M. Wei, Y.L. Xie, L.H. Wang and H. Yang
This study sought to identify and characterize the function of genes as diagnostic markers for Epstein-Barr virus (EBV)-related nasopharyngeal cancer (NPC). The gene expression profile of GSE13597 was downloaded from the Gene Expression Omnibus database, which included 28 EBV-related NPC gene expression profile data sets, 25 d.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.March.17.10
- DOI:
- http://dx.doi.org/10.4238/2014.March.17.10
Molecular cloning and characterization, and prokaryotic expression of the GnRH1 gene obtained from Jinghai yellow chicken
Authors: T. Zhang, G.X. Zhang, K.P. Han, Y. Tang, J.Y. Wang, Q.C. Fan, X.S. Chen, Y. Wei and Y.J. Wang
The gonadotropin-releasing hormone (GnRH) plays an important role in the control of reproductive functions. Recent studies have reported the occurrence of GnRH molecular variants in numerous species. In this study, the GnRH1 gene from Jinghai yellow chicken was cloned by reverse transcriptase-polymeras.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.31.14
- DOI:
- http://dx.doi.org/10.4238/2015.March.31.14
Cloning and expression analysis of heat-shock transcription factor gene CaHsfA2 from pepper (Capsicum annuum L.)
Authors: M. Guo, Y.-X. Yin, J.-J. Ji, B.-P. Ma, M.-H. Lu, and Z.-H. Gong,
The heat-shock transcription factor (Hsf) gene CaHsfA2 (GenBank accession No. JX402923) was cloned from the Capsicum annuum thermotolerant line R9 by combining the techniques electron cloning and rapid amplification of cDNA ends. The gene, which is 1436 bp in length, had an open reading frame of 1089 bp that encoded 362 amino .. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.March.17.14
- DOI:
- http://dx.doi.org/10.4238/2014.March.17.14