Gene
What and why you need to know about beta thalassemia: A genetic disorder
Authors: Nitu Nigam*, S P Verma, Swati Sinha, Kirti Upadhyay, Sanjay Nigam, Vimala Venkatesh, Soniya Nityanand
Thalassemia is a genetic disorder. Now a day’s beta thalassemia is becoming quite prevalent all over the world. The prevalence rate is varied in the different state of India. Beta (β)-thalassemia is of three types. The beta thalassemia major, minor and inter-media. The beta Thalassemia major patients have to be dependent on regular blood transf.. Read More»
- Genet. Mol. Res. 23(4):
Detection of HER2 gene amplification in formalin-fixed and paraffin-embedded breast cancer tissues by quantitative real time polymerase chain reaction in ER and PR-positive HER2 immunohistochemistry 0 or ≥ 2+ breast cancer
Authors: Maisaa Al-Wohhaib*, Salah K Alwaheeb, Ghaneema Enad Al-shammari
Amplification of the human epidermal growth factor receptor 2 (HER2) genes and overexpression of its gene product, the HER2 protein was found in 20% of breast cancers. Genetic instability and hence aberrant HER2 amplification may be associated with breast cancer progression. HER2 status determination plays an important .. Read More»
- Genet. Mol. Res. 23(4):
The ramifications of Darwin's "On the origin of species": From eugenics to modern genomics
Authors: Richard Murdoch Montgomery
This article delves into the historical development and ramifications of divergent theories that have emerged since the publication of Darwin's seminal work, "On the Origin of Species" in 1856. It traces the evolution of thought from Darwin's revolutionary ideas through the controversial era of eugenics, the groundbreaking discovery of D.. Read More»
- Genet. Mol. Res. 23(4):
Evaluation of genetic variability and association of traits in Kabuli chickpea (Cicer arietinum L.) genotypes in East Gojjam Zone, Northwestern, Ethiopia
Authors: Gebremeskel Mequanint Mulu*, Ahadu Menzir, Animaw Dessie
Genetic variability study is an important task for generating genetic information on variability and association of important traits of Kabuli chickpea for further improvement through selection and/or hybridization. In this regard, the study aimed to estimate the magnitude of genetic variation and association of traits among 36 Kabuli chickpea genotypes f.. Read More»
- Genet. Mol. Res. 23(3):
Evaluation of genetic variability in bread wheat (Triticum aestivum L.) genotypes at Holeta, Central Ethiopia
Authors: Fikir Desalew
The experiment was conducted in in alpha-lattice design at Holeta Agricultural Research Center in the 2021 main cropping season with two replications at experimental area of research farm. Analysis of variance revealed that there were statistically significant differences among the genotypes for most of their traits. The varieties showed wider variability.. Read More»
- Genet. Mol. Res. 23(3):
Ethical opinions regarding genetic engineering
Authors: Cagan E. Eren
Genetic engineering is one of the most ethically controversial scientific principles of human history. Biologists, philosophers, experts and even people that have different jobs, each have their own unique opinion on the subject. It is a known fact that public attitudes are one of the key determinants in the development of a research topic. Based on this .. Read More»
- Genet. Mol. Res. 23(2):
Optogenetic approach improves neuroregenerative potential of stem cell-based therapies
Authors: Zahra-Soheila Soheili, Hoda Shams Najafabadi
Neural cells represent very limited regenerative capacity and cannot prevent the progression of central nervous system, and retinal, neurodegenerative diseases such as Alzheimer's, Parkinson's, Retinitis pigmentosa or age related macular degeneration diseases. Stem cell based regenerative strategies revealed successful preclinical transplantation outco.. Read More»
- Genet. Mol. Res. 20(6):
A brief study on Operon model
Authors: Steve Johnson
Operon, hereditary administrative framework found in microbes and their infections in which qualities coding for practically related proteins are bunched along the DNA... Read More»
- Genet. Mol. Res. 20(3):
Genetic code: A major tool for DNA sequencing
Authors: Vinay Gupta
Hereditary code, the arrangement of nucleotides in Deoxyribonucleic Acid (DNA) and Ribonucleic Acid (RNA) that decides the amino corrosive grouping of proteins despite the fact that the straight arrangement of nucleotides in DNA contains the data for protein groupings, proteins are not made straightforwardly from DNA... Read More»
- Genet. Mol. Res. 20(3):
A Short Note on Genetic Medicine on Colon Cancer
Authors: M. Akram
Around 5 to 10 percent of all colorectal malignant growths are brought about by a heritable transformation – a hereditary change that can be given from parent to kid. The two significant subtypes of innate colon disease are called familial adenomatous polyposis (FAP) and Lynch condition, otherwise called genetic nonpolyposis colorectal malignant gro.. Read More»
- Genet. Mol. Res. 20(1):