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Gene Expression

Human Genetics   Research Article

Up-regulation of Id1 in peripheral blood of psoriatic patients

Authors: C. Ronpirin, M. Achariyakul, T. Tencomnao, J. Wongpiyabovorn and W. Chaicumpa

Although the precise causes of psoriasis are unclear, it is widely accepted that psoriasis is a disorder in which factors in the immune system, enzymes, and other biochemical substances that regulate skin cell division are impaired, leading to rapid proliferation of keratinocytes and incomplete keratinization. Expression of th.. Read More»

Genet. Mol. Res. 9(4):
vol9-4gmr963
DOI:
10.4238/vol9-4gmr963
Animal Genetics   Research Article

Gene expression, serum amino acid levels, and growth performance of pigs fed dietary leucine and lysine at different ratios

Authors: H. Garc�­a, A. Morales, A. Araiza, J.K. Htoo and M. Cervantes

We examined 96 pigs (28.1 ± 0.83 kg) to analyze the effect of Leu:Lys ratios on expression of the cationic amino acid transporters b0,+ and CAT-1 in the jejunum and liver as well as myosin expression in 2 muscles to estimate the optimum standardized ileal digestible (SID) Leu:Lys ratio for growth rate and efficiency. A wheat-and wheat bran-based di.. Read More»

Genet. Mol. Res. 14(1):
2015.March.6.6
DOI:
10.4238/2015.March.6.6
Animal Genetics   Research Article

Correlation between liver cancer occurrence and gene expression profiles in rat liver tissue

Authors: C.S. Xu, G.P. Wang, L.X. Zhang, C.F. Chang, J. Zhi and Y.P. Hao

Liver cancer (LC) is generally characterized by malignant cell proliferation and growth; it normally develops in stages that progress from non-specific injury of the liver to liver fibrosis, liver cirrhosis, dysplasia nodules, and liver carcinoma. We used a rat model of diethylnitrosamine (DENA)-induced LC; a Rat Genome 230 2... Read More»

Genet. Mol. Res. 10(4):
2011.December.14.3
DOI:
10.4238/2011.December.14.3
Microbial Genetics   Research Article

Gene expression profile of the plant pathogen Fusarium graminearum under the antagonistic effect of Pantoea agglomerans

Authors: V. Pandolfi, E.C. Jorge, C.M.R. Melo, A.C.S. Albuquerque and H. Carrer

The pathogenic fungus Fusarium graminearum is an ongoing threat to agriculture, causing losses in grain yield and quality in diverse crops. Substantial progress has been made in the identification of genes involved in the suppression of phytopathogens by antagonistic microorganisms; however, limited information regarding respo.. Read More»

Genet. Mol. Res. 9(3):
vol9-3gmr828
DOI:
10.4238/vol9-3gmr828
Plant Genetics   Research Article

Molecular, anatomical and physiological properties of a genetically modified soybean line transformed with rd29A:AtDREB1A for the improvement of drought tolerance

Authors: A.M. Polizel, M.E. Medri, K. Nakashima, N. Yamanaka, J.R.B. Farias, M.C.N. de Oliveira, S.R.R. Marin, R.V. Abdelnoor, F.C. Marcelino-Guimar�£es, R. Fuganti, F.A. Rodrigues, R. Stolf-Moreira, M.A. Beneventi, A.A.P. Rolla, N. Neumaier, K. Yamaguchi-Shinozaki, J.F.C. Carvalho and A.L. Nepomuceno

We evaluated the molecular, anatomical and physiological properties of a soybean line transformed to improve drought tolerance with an rd29A:AtDREB1A construct. This construct expressed dehydration- responsive element binding protein DREB1A from the stress-inducible rd29A promoter. The greenhouse growth test included four rand.. Read More»

Genet. Mol. Res. 10(4):
2011.October.21.4
DOI:
10.4238/2011.October.21.4
Plant Genetics   Research Article

Transcription factors expressed in soybean roots under drought stress

Authors: S.S. Pereira, F.C.M. Guimar�£es, J.F.C. Carvalho, R. Stolf-Moreira, M.C.N. Oliveira, A.A.P. Rolla, J.R.B. Farias, N. Neumaier and A.L. Nepomuceno

To gain insight into stress-responsive gene regulation in soybean plants, we identified consensus sequences that could categorize the transcription factors MYBJ7, BZIP50, C2H2, and NAC2 as members of the gene families myb, bzip, c2h2, and nac, respectively. We also investigated the evolutionary relationship of these transcript.. Read More»

Genet. Mol. Res. 10(4):
2011.October.21.5
DOI:
10.4238/2011.October.21.5
Bioinformatics   Research Article

Combining P values to improve classification of differential gene expression in the HTself software

Authors: D.A. Cortez, A.P. Tonon, P. Colepicolo and R.Z.N. V�ªncio

HTself is a web-based bioinformatics tool designed to deal with the classification of differential gene expression in low replication microarray studies. It is based on a statistical test that uses self-self experiments to derive intensity-dependent cutoffs. We developed an extension of HTself, originally released in 2005, by .. Read More»

Genet. Mol. Res. 10(4):
2011.December.5.5
DOI:
10.4238/2011.December.5.5
Medical Genetics   Research Article

Identification of critical TF-miRNA-mRNA regulation loops for colorectal cancer metastasis.

Authors: C. Wang, D.Z. Hu and J.Z. Liu

To explore the potential cause of colorectal cancer metastasis, gene expression profiles, GSE21510, and miRNA expression profiles, GSE48074, were downloaded from the Gene Expression Omnibus database. Differentially expressed genes in metastatic colorectal and non metastatic colorectal cancer compared with the normal samples were identified via the limma p.. Read More»

Genet. Mol. Res. 14(2):
2015.May.22.19
DOI:
10.4238/2015.May.22.19
Medical Genetics   Research Article

Identification of critical TF-miRNA-mRNA regulation loops for colorectal cancer metastasis

Authors: C. Wang D.Z. Hu and J.Z. Liu

To explore the potential cause of colorectal cancer metastasis, gene expression profiles, GSE21510, and miRNA expression profiles, GSE48074, were downloaded from the Gene Expression Omnibus database. Differentially expressed genes in metastatic colorectal and non metastatic colorectal cancer compared with the normal samples were identified via the limma p.. Read More»

Genet. Mol. Res. 14(2):
2015.May.22.19
DOI:
10.4238/2015.May.22.19
Animal Genetics   Research Article

Analysis of skin color change and related gene expression after crossing of Dongxiang black chicken and ISA layer

Authors: X.D. Zhang, H.H. Wang, C.X. Zhang, Q.H. Li, X.H. Chen and L.F. Lou

This study evaluated the effects of the autosomal dominant Fm gene in conjunction with the sex-linked Id gene on skin color and related gene expression. Ten Dongxiang black cocks were selected to build ten families by mating 60 individuals of ISA B-line layers. The skin color of the F1 generation was observed at different time points. At 126 days, 36 chic.. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.28.7
DOI:
http://dx.doi.org/10.4238/2015.September.28.7