Gene Expression
Defective eyelid leading edge cell migration in C57BL/6-corneal opacity mice with an â??eye open at birthâ? phenotype
Authors: L.C. Wu, C. Liu, M.R. Jiang ,Y.M. Jiang, Q.H. Wang, Z.Y. Lu, S.J. Wang, W.L. Yang and Y.X. Shao
Development of the eyelid requires coordination of the cellular processes involved in proliferation, cell size alteration, migration, and cell death. C57BL/6J-corneal opacity (B6-Co) mice are mutant mice generated by the administration of N-ethyl-N-nitrosourea (100 mg/kg). They exhibit the eyelids open at birth phenotype, abnormal round cell shape from ti.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15036741
- DOI:
- 10.4238/gmr.15036741
Temporal and spatial expression of Smads and their correlation with YAP1 expression in sheep
Authors: W. Gao, R. S, W. Sun, Q.Z. Wang, X.Y. Lv, J.J. Bao, J.R. Yu, L.H. Wang, H.H. Musa and L. Chen
The temporal and spatial patterns of Smad and Yes-associated protein 1 (YAP1) expression were investigated in skeletal muscle (gastrocnemius muscle and extensor digitorum longus) at different growth stages (2 days old, 2 and 6 months old) in Hu sheep. Smads were differentially expressed in sheep skeletal muscle, with high expression in the gastrocnemius m.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15037715
- DOI:
- 10.4238/gmr.15037715
Gene expression profiling analysis of 5-hydroxytryptamine signaling pathway in rat regenerating liver and different types of liver cells
Authors: C.F. Chang, J. Yang, W.M. Zhao, Y. Li, P.J. Guo, M.H. Li, Y. Zhou and C.S. Xu
We examined the gene expression profiles of the 5-hydroxytryptamine signaling pathway in the regenerating liver and 8 types of liver cells during rat liver regeneration, and explored expression differences in 5-hydroxytryptamine signaling pathway genes at the level of tissues and cells, as well as the role of the pathway on liver regeneration. Eight types.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.15.4
- DOI:
- http://dx.doi.org/10.4238/2015.April.15.4
Expression of drought tolerance genes in tropical upland rice cultivars (Oryza sativa)
Authors: R.D.D. Silveira, F.R.M. Abreu, S. Mamidi, P.E. McClean, R.P. Vianello, A.C. Lanna, N.P. Carneiro and C. Brondani
Gene expression related to drought response in the leaf tissues of two Brazilian upland cultivars, the drought-tolerant Douradão and the drought-sensitive Primavera, was analyzed. RNA-seq identified 27,618 transcripts in the Douradão cultivar, with 24,090 (87.2%) homologous to the rice database, and 27,221 transcripts in the Primavera cultiv.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.27.6
- DOI:
- 10.4238/2015.July.27.6
Analysis of SLC11A1 gene expression in healthy water buffalo (Bubalus bubalis) blood cells using qPCR
Authors: A. Cris? , G. De Matteis, M.C. Scat? and B. Moioli
SLC11A1 (solute carrier family 11 member 1 protein) gene influences the initial phase of bacterial cellular infections through macrophage activation. Recent literature on buffalo has attempted to associate the genotype of the polymorphic microsatellite located in the 3ê??untranslated region (3ê??UTR) of the gene, with either susceptibility to brucel.. Read More»
- Genet. Mol. Res. 12(4):
- 201
- DOI:
- 10.4238/201
Cloning and bioinformatic analysis of full-length novel pepper (Capsicum annuum) genes TAF10 and TAF13
Authors: J.F. Wen, J.L. Huo, H.X. Chen, C.H. Ma, H. Jiang, H.S. Zhu, H. Zhou and M.H. Deng
We isolated two TATA-binding protein-associated factor (TAF) genes, TAF10 and TAF13, from pepper (Capsicum annuum). The complete coding sequences were amplified using reverse transcriptase-PCR on the basis of conserved sequence information of eggplant and several other plant species. Nucleotide sequence analysis of these two genes revealed that the pepper.. Read More»
- Genet. Mol. Res. 12(4):
- 2013
- DOI:
- 10.4238/2013
Three branches of phospholipase C signaling pathway promote hepatocyte growth in rat liver regeneration
Authors: G.G. Xu, Z. Geng, X.C. Zhou, Y.G. He, T.T. He, J.X. Mei,Y.J. Yang, Y.Q. Liu and C.S. Xu
In general, the phospholipase C (PLC) signaling pathway is involved in many physiological activities, including cell growth. However, little is known regarding how the PLC signaling pathway participates in regulating hepatocyte (HC) growth during liver regeneration (LR). To further explore the influence of the PLC signaling pathway on HCs at the cellular .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.29.3
- DOI:
- 10.4238/2015.May.29.3
Inhibitory effect of alternatively spliced RAGEv1 on the expression of NF-kB and TNF-?± in hepatocellular carcinoma cells
Authors: T. Lertwittayapon, T. Tencomnao and R. Santiyanont
Binding of specific ligands to the receptor for advanced glycation end-products (RAGE) can trigger a series of signal transductions, which leads to pathogenesis in many chronic degenerative diseases, including cancer. Alternative splicing of RAGE mRNA has resulted in many variants, including RAGE variant 1 (RAGEv1). This parti.. Read More»
- Genet. Mol. Res. 11(2):
- http://dx.doi.org/2012.June.29.3
- DOI:
- http://dx.doi.org/10.4238/2012.June.29.3
Molecular cloning and expression profile of an ATP-binding cassette (ABC) transporter gene from the hemipteran insect Nilaparvata lugens
Authors: W.J. Zha, S.H. Li, L. Zhou, Z.J. Chen, K. Liu, G.C. Yang, G. Hu, G.C. He and A.Q. You
The ATP-binding cassette (ABC) transporters belong to a large superfamily of proteins that have important physiological functions in all living organisms. In insects, ABC transporters have important functions in the transport of molecules, and are also involved in insecticide resistance, metabolism, and development. In this study, the Nilaparvata lugens S.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.26
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.26
Identification of COL6A1 as a differentially expressed gene in human astrocytomas
Authors: A. Fujita, J.R. Sato, F. Festa, L.R. Gomes, S.M. Oba-Shinjo,S.K.N. Marie, C.E. Ferreira and M.C. Sogayar
Diffuse infiltrating gliomas are the most common tumors of the central nervous system. Gliomas are classified by the WHO according to their histopathological and clinical characteristics into four classes: grade I (pilocytic astrocytoma), grade II (diffuse astrocytoma), grade III (anaplastic astrocytoma), and grade IV (gliobla.. Read More»
- Genet. Mol. Res. 7(2):
- vol7-2gmr432
- DOI:
- 10.4238/vol7-2gmr432