All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Gene Expression

Human Genetics   Research Article

Constructing gene network based on biclusters of expression data

Authors: F. Liu, L. Yang, Z.Z. Tian, P. Wu and S.L. Sun

Two genes can be co-regulated and possibly have the similar function if they are similarly expressed, which provides a theoretical basis for construction of gene regulatory networks using gene expression data. Herein, a new method of gene regulatory network was constructed based on biclusters in this paper. Given a bicluster, .. Read More»

Genet. Mol. Res. 15(2):
Animal Genetics   Research Article

Molecular cloning and expression analysis of female sterile homeotic gene (fsh) in the oriental river prawn Macrobrachium nipponense

Authors: W.Y. Zhang, S.F. Jiang, Y.W. Xiong, H.T. Fu1,, H. Qiao, S.M. Sun, Y.S. Gong and S.B. Jin

The gene female sterile homeotic (fsh) plays crucial roles in molecular function, including protein kinase activity and DNA binding, which are involved in biological processes such as terminal region determination and negative regulation of DNA-dependent transcription. Although fsh has been found in Drosophila melanogaster, little is known regarding its e.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.30.4
DOI:
http://dx.doi.org/10.4238/2015.April.30.4
Animal Genetics   Research Article

MicroRNA screening and functional study of obliterative bronchiolitis in a rat model simulating lung transplantation

Authors: J. Wang, H. Cao, X. Hong, G.H. Chen, H.M. Fan, Q.C. Li, Z.M. Liu and K.F. Li

The aim of this study was to provide the experimental basis for effective prevention and treatment of obliterative bronchiolitis (OB) by studying the changes on the microRNA (miRNA) expression profile after an orthotopic tracheal transplantation (OTT) simulating lung transplantation (LT). The OTT was performed on inbred rats to establish an OB animal mode.. Read More»

Genet. Mol. Res. 14(4):
2015.December.29.40
DOI:
10.4238/2015.December.29.40
Microbial Genetics   Research Article

Gene expression in Chromobacterium violaceum

Authors: Rosane Silva, J?ºlia R. Araripe, Edson Rondinelli, Tur?¡n P. ??rm?©nyi

The repertoire of 4,431 open reading frames (ORFs), eight rRNA operons and 98 tRNA genes of Chromobacterium violaceum must be expressed in a regulated manner for successful adaptation to a wide variety of environmental conditions. To accomplish this feat, the organism relies on protein machineries involved in transcription, RN.. Read More»

Genet. Mol. Res. 3(1):
Microbial Genetics   Research Article

Stage-specific gene expression during Trypanosoma cruzi metacyclogenesis

Authors: Andr?©a Rodrigues ?vila, Bruno Dallagiovanna, Sueli Fumie Yamada-Ogatta, Viviane Monteiro-G?³es, St?ªnio Perdig?£o Fragoso Marco Aur?©lio Krieger, Samuel Goldenberg

The process of Trypanosoma cruzi metacyclogenesis involves the transformation of noninfective epimastigotes into metacyclic trypomastigotes, which are the pathogenic form. The analysis of stage-specific genes during T. cruzi metacyclogenesis may provide insight into the mechanisms involved in the regulation of gene expression .. Read More»

Genet. Mol. Res. 2(1):
Microbial Genetics   Research Article

Control of gene expression and genetic manipulation in the Trypanosomatidae

Authors: Santuza M.R. Teixeira, Wanderson D. da Rocha

Mechanisms controlling gene expression in trypanosomatids depend on several layers of regulation, with most regulatory pathways acting at a post-transcriptional level. Consequently, these parasites can follow the rapid changes associated with transitions between the insect vector and the mammalian host, with instant reprogramm.. Read More»

Genet. Mol. Res. 2(1):
Animal Genetics   Research Article

Growth hormone mRNA expression in the pituitary of Bos indicus and Bos taurus x Bos indicus crossbred young bulls treated with recombinant bovine somatotropin

Authors: S.M.Z. Di Mauro, L.R. Furlan, M.I.T. Ferro, M. Macari andJ.A. Ferro

The effects of breed and of recombinant bovine somatotropin (rbST) treatment on growth hormone gene expression were studied in young bulls. The experiment was completely randomized in a [2 x 2]-factorial arrangement, using two levels of rbST (0 or 250 mg/animal/14 days), and two breed groups (Nelore and Simmental x Nelore cros.. Read More»

Genet. Mol. Res. 1(4):