Gene
Expression profiling analysis of hypoxic pulmonary disease
Authors: L. Zhou, L.M. Wang, H.M. Song, Y.Q. Shen, W.J. Xu, J.H. Xu, Y. Liu, W.W. Yan and J.F. Jiang
Exposure of humans to low levels of environmental oxygen results in alveolar hypoxia and normally causes chronic pulmonary hypertension and morphological alterations of precapillary pulmonary vessels. In this study, the microarray dataset GSE11341 was used to identify potential differentially expressed genes related with human lung microvascular endotheli.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.7.2
- DOI:
- 10.4238/2013.October.7.2
Effect of the Jianpi Bushen Prescription on expressions of the Wnt3a and Cyclin D1 genes in radiation-damaged mice
Authors: D.C. He*, J.J. Xiao*, Y. Zhang, H. Lin, X.J. Ding and Y. Tu
The effects of the traditional Chinese drug Jianpi Bushen Prescription (JBP) were investigated on expressions of Wnt3a and Cyclin D1 genes in radiation-damaged mice. The radiation damage model was induced in Kumming mice by single total body irradiation treatment for 9 days. Mice were divided into the radiation group, low-dose (100%) JBP group, high-dose .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.3.1
- DOI:
- 10.4238/2013.October.3.1
Different impact of two mutations of a novel compound heterozygous protein C deficiency with late onset thrombosis
Authors: L.-H. Yang, M.-S. Wang, F.-X. Zheng, J. Li , Y. Chen, Y.-H. Jin, H.-X. Xie, X.-L. Yang and B.-C. Chen
We investigated the alteration of coagulation state in a protein C (PC) deficiency pedigree and the impact of the PC gene mutations. The pedigree of a proband with cerebral hemorrhagic infarction had sixteen members with four generations. The plasma levels of PC activity (PC:A), protein S activity (PS:A), factor V:C and factor VIII:C, and routine coagulat.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.16.5
- DOI:
- 10.4238/2014.April.16.5
Screening of the residual normal ovarian tissue adjacent to orthotopic epithelial ovarian carcinomas in nude mice
Authors: G.H. Zhu, S.T. Wang, M.Z. Yao, J.H. Cai, C.Y. Chen, Z.X. Yang, L. Hong and S.Y. Yang
The objective of this study was to explore the feasibility and methods of screening the residual normal ovarian tissue adjacent to orthotopic ovarian carcinomas in nude mice. Human epithelial ovarian cancer cells (OVCAR3) were subcutaneously implanted for a tumor source and ovarian orthotopic transplantation. The cancer tissue.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.16.6
- DOI:
- 10.4238/2014.April.16.6
Development of EST-SSR markers related to salt tolerance and their application in genetic diversity and evolution analysis in Gossypium
Authors: B.H. Wang, P. Zhu, Y.L. Yuan, C.B. Wang, C.M. Yu, H.H. Zhang, X.Y. Zhu, W. Wang, C.B. Yao, Z.M. Zhuang and P. Li
Salt stress is becoming one of the major problems in global agriculture with the onset of global warming, an increasing scarcity of fresh water, and improper land irrigation and fertilization practices, which leads to reduction of crop output and even causes crop death. To speed up the exploitation of saline land, it is a good.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.13.1
- DOI:
- http://dx.doi.org/10.4238/2014.May.13.1
�±-1,3-N-acetylgalactose aminotransferase gene 539G>C mutation leads to the A2B isoform
Authors: J.J. Lin, X.D. Wang and S.Y. Zhu
In this study, the phenotypic identification and molecular mechanism of one case of an A2B subtype pedigree was investigated. ABO blood groupings were identified by serological methods and sequence amplification was performed by polymerase chain reaction (PCR) using TA cloning and DNA sequencing analysis to identify the pedigr.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.16.7
- DOI:
- 10.4238/2014.April.16.7
Genome-wide identification and expression profiling of the fatty acid desaturase gene family in the silkworm, Bombyx mori
Authors: Q.M. Chen, D.J. Cheng, S.P. Liu, Z.G. Ma, X. Tan and P. Zhao
Fatty acid desaturases exist in all living organisms and play important roles in many different biologic processes, such as fatty acid metabolism, lipid biosynthetic processes, and pheromone biosynthetic processes. Using the available silkworm genome sequence, we identified 14 candidate fatty acid desaturase genes. Eleven gene.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.13.2
- DOI:
- http://dx.doi.org/10.4238/2014.May.13.2
Diversity resistance to Puccinia striiformis f. sp Tritici in rye chromosome arm 1RS expressed in wheat
Authors: M.Y. Yang, T.H. Ren, B.J. Yan, Z. Li and Z.L. Ren
The 1BL.1RS wheat-rye translocation contained in the Russian cultivar Aurora has been the most widespread alien translocation in wheat-breeding programs all over the world. However, following the prevalence of new biotypes of the pathogens, disease-resistance genes in this translocation chromosome have been overcome and consequently they have been elimina.. Read More»
- Genet. Mol. Res. 13(4):
Genetic diversity of Saccharum spontaneum from geographical regions of China assessed by simple sequence repeats
Authors: L.N. Fan, H.H. Deng, Q.W. Luo, H.Y. He, Y. Li, Q.N. Wang, Z.X. Huang, J.T. Wu, Q.W. Li, S.M. Liu and Y.W. Qi
Saccharum spontaneum is the most variable wild relative of sugarcane with potential for use in sugarcane improvement programs. In order to help preserve and exploit this species, 152 accessions from eight major geographical regions in China, including Hainan, Guangdong, Guangxi, Yunnan, Sichuan, Guizhou, Fujian, and Jiangxi pr.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.26.1
- DOI:
- 10.4238/2013.November.26.1
Polymorphisms in the XRCC1 gene are associated with treatment response to platinum chemotherapy in advanced non-small cell lung cancer patients based on meta-analysis
Authors: L. Li, C. Wan and F.Q. Wen
X-ray repair cross complementing group 1(XRCC1) polymorphisms have been implicated in interindividual variability of efficacy of platinum chemotherapy for treating non-small cell lung cancer (NSCLC); however, results of different studies have been inconsistent. We conducted a meta-analysis to investigate the association betwee.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.16.1
- DOI:
- http://dx.doi.org/10.4238/2014.May.16.1