Gene
Genetic variation in wild populations of the tuber crop Amorphophallus konjac (Araceae) in central China as revealed by AFLP markers
Authors: C. Pan, A.W. Gichira and J.M. Chen
Amorphophallus konjac is an economically important crop. In order to provide baseline information for sustainable development and conservation of the wild plant resources of A. konjac, we studied the genetic diversity and population structure of this species using amplified fragment length polymorphism (AFLP) molecular markers. We sampled 139 individuals .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.24
- DOI:
- 10.4238/2015.December.28.24
High polymorphism at microsatellite loci in the Chinese donkey
Authors: R.F. Zhang, W.M. Xie, T. Zhang and C.Z. Lei
To reveal the genetic diversity and phylogenetic relationships between Chinese donkey breeds, 415 individuals representing ten breeds were investigated using ten microsatellite markers. The observed number of alleles, mean effective number of alleles (NE), mean expected heterozygosity (HE), and polymorphic information content .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028291
- DOI:
- 10.4238/gmr.15028291
Analysis and application of ATP7B gene mutations in 35 patients with hepatolenticular degeneration
Authors: Y.N. Zong and X.D. Kong
We investigated the genetic mutations involved in Wilson’s disease to improve prenatal genetic diagnosis and presymptomatic diagnosis. The polymerase chain reaction (PCR) was used to amplify the exons and exon-intron boundaries of the ATP7B gene in 35 Wilson’s disease pedigrees. The PCR products were further analyzed by Sanger sequencing. Pren.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.25
- DOI:
- 10.4238/2015.December.28.25
Ancestry analysis of locally adapted Crespa goats from southernmost Brazil
Authors: D.D. Lopes, G.P. Fern�¡ndez, M. Poli, G.R.P. Moreira, G.L. Gon�§alves and T.R.O. Freitas
Crespa goats are phenotypically similar to the Angora breed, and are traditionally reared in small, low-tech farms in southernmost Brazil. Whether they represent degenerated remnants of pure Angora goats or result from foreign breeds introduced during colonial times and recently mixed with commercial breeds is unknown. Since t.. Read More»
- Genet. Mol. Res. 15(2):
Data integration for identification of important transcription factors of STAT6-mediated cell fate decisions
Authors: M. Jargosch, S. Kr�¶ger, E. Gralinska, U. Klotz, Z. Fang, W. Chen, U. Leser, J. Selbig, D. Groth and R. Baumgrass
Data integration has become a useful strategy for uncovering new insights into complex biological networks. We studied whether this approach can help to delineate the signal transducer and activator of transcription 6 (STAT6)-mediated transcriptional network driving T helper (Th) 2 cell fate decisions. To this end, we performe.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028493
- DOI:
- 10.4238/gmr.15028493
Male carriers of balanced reciprocal translocations in Northeast China: sperm count, reproductive performance, and genetic counseling
Authors: H.G. Zhang, R.X. Wang, L.L. Li, W.T. Sun, H.Y. Zhang and R.Z. Liu
Balanced chromosomal translocations in men can cause failure of spermatogenesis owing to meiotic impairment. Male carriers may exhibit normozoospermia, although clinical manifestations can include oligozoospermia or azoospermia, oligozoospermia or normozoospermia. Here, we reported the characteristics of balanced reciprocal translocations in men from nort.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.28
- DOI:
- 10.4238/2015.December.28.28
Molecular tracing of white muscardine in Asian corn borer using inter-simple sequence repeat (ISSR) analysis
Authors: B.J. Hu, L.N. Xu, Z.Y. Zhou, F. Hu, F.G. Luan, X. Chen and Z.Z. Li
Beauveria bassiana is a soil fungus that parasitizes arthropod species, and is used to control the Asian corn borer in Northeast China. In this study, B. bassiana was investigated in Xiaoxian County and Baicheng City, and the results were compared with those of Gongzhuling City, where the fungus was not applied. Using the inter-simple sequence repeat (ISS.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.21
- DOI:
- 10.4238/2015.December.28.21
Multiple sequence alignment based on combining genetic algorithm with chaotic sequences
Authors: C. Gao, B. Wang, C.J. Zhou and Q. Zhang
In bioinformatics, sequence alignment is one of the most common problems. Multiple sequence alignment is an NP (nondeterministic polynomial time) problem, which requires further study and exploration. The chaos optimization algorithm is a type of chaos theory, and a procedure for combining the genetic algorithm (GA), which use.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028788
- DOI:
- 10.4238/gmr.15028788
Superoxide radical-generating compounds activate a predicted promoter site for paraquat-inducible genes of the Chromobacterium violaceum bacterium in a dose-dependent manner
Authors: J.E. Gabriel, E.P. Guerra-Slompo, E.M. de Souza, F.A.L. de Carvalho, H.M.F. Madeira and A.T.R. de Vasconcelos
The purpose of the present study was to functionally evaluate the influence of superoxide radical-generating compounds on the heterologous induction of a predicted promoter region of open reading frames for paraquat-inducible genes (pqi genes) revealed during genome annotation analyses of the Chromobacterium violaceum bacterium. A 388-bp fragment correspo.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.21.20
- DOI:
- 10.4238/2015.August.21.20
Genetic characterization of red-colored heartwood genotypes of Chinese fir using simple sequence repeat (SSR) markers
Authors: H.J. Duan, R.Y. Hu, B. Wu, D.X. Chen, K.Y. Huang, J. Dai, Q. Chen, Z.C. Wei, S. Cao, Y.H. Sun and Y. Li
The present study investigated the genetic characterization of red-colored heartwood Chinese fir [Cunninghamia lanceolata (Lamb.) Hook.] in Guangxi using 21 simple sequence repeat (SSR) markers and analyzes of the genetic variation (N = 149) in samples obtained from five sites in Guangxi Province, China. The number of different alleles and the Shannon&rsq.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.2
- DOI:
- 10.4238/2015.December.28.2