Gene
Constructing gene network based on biclusters of expression data
Authors: F. Liu, L. Yang, Z.Z. Tian, P. Wu and S.L. Sun
Two genes can be co-regulated and possibly have the similar function if they are similarly expressed, which provides a theoretical basis for construction of gene regulatory networks using gene expression data. Herein, a new method of gene regulatory network was constructed based on biclusters in this paper. Given a bicluster, .. Read More»
- Genet. Mol. Res. 15(2):
Correlation of CYP1A1 and GSTM1 gene polymorphisms and environmental factors to familial aggregation of esophageal cancer among the Kazakh ethnic group in Xinjiang
Authors: M. Zeng, Y. Lv, H.F. Wang, H.A. Yiguli, J.R. Zhang and A. Yisikandaer
This study aimed to investigate the correlation of CYP1A1 and GSTM1 gene polymorphisms and environmental factors to familial aggregation of esophageal cancer (EC) among the Kazakh ethnic group in Xinjiang. CYP1A1 and GSTM1 gene polymorphisms were detected using peripheral blood from 86 subjects belonging to families with EC and 82 control subjects. Additi.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.19
- DOI:
- 10.4238/2015.December.29.19
Genetic parameters for test day somatic cell score in Brazilian Holstein cattle
Authors: C.N. Costa, G.G. Santos, J.A. Cobuci, G. Thompson and J.G.V. Carvalheira
Selection for lower somatic cell count has been included in the breeding objectives of several countries in order to increase resistance to mastitis. Genetic parameters of somatic cell scores (SCS) were estimated from the first lactation test day records of Brazilian Holstein cows using random-regression models with Legendre polynomials (LP) of the order .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.21
- DOI:
- 10.4238/2015.December.29.21
Interleukin-10 polymorphisms and nasopharyngeal carcinoma risk: a meta-analysis
Authors: Y.-F. Yu, Z.-G. Han, W.-B. Guo, G.-J. Zhang, J.-K. Yang, F.-L. Wu, Q.-Y. Ou, Y.-H. Li, X.-Y. Cai, Z.-N. Zhan, J.-H. Chen, W.-L. Xie, L. Tang and C.-D. Liu
It has been reported that interleukin-10 (IL-10) promoter genes (1082 A/G, 819 T/C, 592 A/C) are associated with nasopharyngeal carcinoma (NPC). However, the results remain controversial and ambiguous. To resolve inconsistencies in published data, we performed a meta-analysis to ascertain the association between IL-10 polymorphisms and NPC risk. Two case-.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.1
- DOI:
- 10.4238/2015.December.29.1
Microsatellite DNA markers and their correlation with growth traits in mandarin fish (Siniperca chuatsi)
Authors: L.F. Sun, J. Li, X.F. Liang, T.L. Yi, L. Fang, J. Sun, Y.H. He, X.N. Luo, Y.Q. Dou and M. Yang
The mandarin fish (Siniperca chuatsi) is a traditionally cultured freshwater fish with high commercial value in China. To facilitate marker-assisted selection in genetic improvement of this species, 120 microsatellite markers from the literature were characterized in the 25 largest and 25 smallest individuals. Eighteen polymorphic loci were then used to g.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.22
- DOI:
- 10.4238/2015.December.29.22
ORMDL3 variants associated with bronchiolitis susceptibility in a Chinese population
Authors: X.T. Liu, L. Ren, L.L. Zhou, Q.Y. Xiao, Y. Deng and E.M. Liu
Recent studies revealed common genetic risks for both viral bronchiolitis and asthma. Genome-wide association studies revealed that rs7216389 in the ORMDL3 gene is associated with childhood asthma. We conducted a case-control study examining the associations between ORMDL3 polymorphisms (rs7216389, rs12603332, and rs11650680) and bronchiolitis susceptibil.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.25
- DOI:
- 10.4238/2015.December.29.25
Analysis of CYP1A1 and COMT polymorphisms in women with cervical cancer
Authors: J.P. Kleine, C.M. Camargo-Kosugi, C.V. Carvalho, F.C. Silva and I.D.C.G. Silva
The aim of this case-control study was to obtain a comprehensive panel of genetic polymorphisms present only in genes (cytochrome P-450 1A1 - CYP1A1 and catechol-O-methyl transferase - COMT) within the metabolic pathway of sex steroids and determine their possible associations with the presence or absence of cervical cancer. Genotypes of 222 women were an.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.3
- DOI:
- 10.4238/2015.December.29.3
Molecular cloning and expression analysis of female sterile homeotic gene (fsh) in the oriental river prawn Macrobrachium nipponense
Authors: W.Y. Zhang, S.F. Jiang, Y.W. Xiong, H.T. Fu1,, H. Qiao, S.M. Sun, Y.S. Gong and S.B. Jin
The gene female sterile homeotic (fsh) plays crucial roles in molecular function, including protein kinase activity and DNA binding, which are involved in biological processes such as terminal region determination and negative regulation of DNA-dependent transcription. Although fsh has been found in Drosophila melanogaster, little is known regarding its e.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.30.4
- DOI:
- http://dx.doi.org/10.4238/2015.April.30.4
Analysis of drug-resistant gene detection of blaOXA-like genes from Acinetobacter baumannii
Authors: D.K. Yang, H.J. Liang, H.L. Gao, X.W. Wang and Y. Wang
Our study determines the resistance gene profile of a set of Acinetobacter baumannii hospital isolates. A. baumannii is responsible for nosocomial outbreaks and sporadic infections. We extracted and PCR amplified bacterial DNA isolated from patients with ages below 60 years (23.36%) and above 60 years (76.64%). Most of the patients were admitted in the IC.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.7
- DOI:
- 10.4238/2015.December.29.7
Assessment of genetic diversity of cucumber cultivars in China based on simple sequence repeats and fruit traits
Authors: Y.T. Yang, Y. Liu, F. Qi, L.L. Xu, X.Z. Li, L.J. Cong, X. Guo, S.X. Chen and Y.L. Fang
The cucumber (Cucumis sativus L.) is an important crop grown worldwide. In this study, the genetic diversity of 42 cucumber cultivars in China was analyzed using 51 pairs of simple sequence repeat (SSR) primers. These primers identified 129 polymorphic loci, 95.6% of which were polymorphic. The mean effective number of alleles, mean Nei’s gene diver.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.10
- DOI:
- 10.4238/2015.December.29.10