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Gene

Human Genetics   Research Article

Predominance of the A allele but no association of the KCNJ11 rs5219 E23K polymorphism with Type 2 Diabetes in a Nigerian population

Authors: Godwill Azeh Engwa, Friday Nweke Nwalo, Chosen E. Obi, Christie Onyia, Opeolu Oyejide Ojo Wilfred Fon Mbacham, Benjamin Ewa Ubi

Though the rs5219 E23K variant of the KCNJ11 gene is commonly known to be associated with Type 2 diabetes (T2D) in Caucasian and Asian populations, little or none of such findings have been revealed in Nigeria. Hence, this study was aimed to assess the relationship between E23K polymorphic variant of the KCNJ11 gene and T2D in.. Read More»

Genet. Mol. Res. 17(1):
gmr16039889
DOI:
10.4238/gmr16039889
Human Genetics   Research Article

The Disruption of Klf6-Related Super-Enhancer Induces Growth Inhibition and Apoptosis in Human HepG2 Cells

Authors: KumChol Ri, KumChol Kim, SunHyok Kong, JuHua Ri

Klf6 is a member of the Krüppel-like factor family, which is a group of zinc finger transcription factors involved in differentiation and development. In general, Klf6 gene plays an important role in growth-related signal transduction pathways, cell proliferation, apoptosis, and angiogenesis. Recently, the Klf6 gene is co.. Read More»

Genet. Mol. Res. 17(1):
gmr16039888
DOI:
10.4238/gmr16039888
Plant Genetics   Research Article

Estimate of natural cross-pollination rate of Capsicum annuum using a codominant molecular marker associated with fruit pungency

Authors: EV Justino, MEN Fonseca, ME Ferreira, LS Boiteux, PP Silva, WM Nascimento

The production of seeds with high genetic quality requires accurate estimates of the natural cross-pollination rate in cultivated Capsicum species. This is important in order to establish the most suitable isolation distance among fields of distinct genotypes, to minimize the risk of genetic contamination and to ensure that th.. Read More»

Genet. Mol. Res. 17(1):
gmr16039887
DOI:
10.4238/gmr16039887
Plant Genetics   Research Article

Agronomic performance of plantain genotypes and genetic variability using Ward-MLM algorithm

Authors: Z. S. Gon?§alves, D. R. S. da Inven?§?£o, C. A. da S. Ledo, C. F. Ferreira, E. P. Amorim

Plantains in Brazil are produced from the `Terra Maranhão’, ‘Terrinha’ and ‘D´Angola’ cultivars, which are all susceptible to black Sigatoka, weevils and nematodes. Therefore, the development of resistant plantain cultivars with agronomic characteristics aligned with market demands i.. Read More»

Genet. Mol. Res. 17(1):
gmr16039882
DOI:
10.4238/gmr16039882
Human Genetics   Research Article

Retrospective Investigation of Interleukin 1 and 6 Gene Polymorphism among Elderly Patients with Sarcopenia in the Turkish Population

Authors: Pinar Tosun Tasar

Introduction: Sarcopenia, one of the geriatric syndromes, is defined as generalized and progressive reduction in skeletal muscle mass accompanied by loss of muscle strength and/or function. There is a paucity of research in the Turkish population about the effects of interleukin 1 (IL-1) and IL-6 gene polymorphism on sarcopeni.. Read More»

Genet. Mol. Res. 17(1):
gmr16039881
DOI:
10.4238/gmr16039881
Plant Genetics   Research Article

New insights into the genetic diversity and species identification of the native apricots in Southern Xinjiang of China

Authors: Ling Guo, Hui Li, Zheng-rong Luoa

Apricot is a staple stone fruit crop cultivated in Southern Xinjiang of China. This crop is important for the rural communities, as they generate significant employment and income. Here, seventy-eight apricot genotypes, including seventy-six common apricots (Prunus armeniaca L.) and two purple apricots (Prunus dasycarpa Ehrh.).. Read More»

Genet. Mol. Res. 17(1):
gmr16039874
DOI:
10.4238/gmr16039874
Plant Genetics   Review Article

Hierarchical outcrossing among and within fruits in Bertholletia excelsa Bonpl. (Lecythidaceae) open-pollinated seeds

Authors: L.D. Giustina, A.B. Baldoni, H. Tonini, V.C.R. Azevedo, L.G. Neves, F.D. Tardin, A.M. Sebbenn

Knowing the mating patterns is important to determine the number of trees necessary for seed collection for conservation ex situ, tree breeding and environmental reforestation purposes. We investigated B. excelsa individuals and fruits, to check mating system index variations in a population by using open-pollinated seeds whic.. Read More»

Genet. Mol. Res. 17(1):
gmr16039872
DOI:
10.4238/gmr16039872
Plant Genetics   Research Article

Molecular Characterization and Differential Interaction of Xanthomonas axonopodis pv. phaseoli and Xanthomonas fuscans subsp. fuscans with Common Beans (Phaseolus vulgaris)

Authors: De Paiva BAR, Wendland A , Borba TC , Ara?ºjo LG

The common bacterial blight, caused by Xanthomonas axonopodis pv. phaseoli (Xap) and X. fuscans subsp. fuscans (Xff), is one of the most important dry bean diseases of bacterial etiology. The present work aimed to study the genetic structure among and within populations, and also identify the pathogenic variability of Xap and .. Read More»

Genet. Mol. Res. 17(1):
gmr16039871
DOI:
10.4238/gmr16039871
Plant Genetics   Research Article

Genetic diversity assessment of Allium cepa L. cultivars from Bosnia and Herzegovina using SSR makers

Authors: Lutvija Kari??, Maryam Golzardi, Petar Glamo?lija, Jasmin ? utkovi??

The five most common cultivars from the genus Allium cepa L. in Bosnia and Herzegovina (BiH) were analysed, focusing on Konjic onion. Seven SSR markers for genetic similarity analysis were used to address the genetic backgrounds. The polymorphic relationship between the SSR markers was analyzed by using Polymorphic Informatio.. Read More»

Genet. Mol. Res. 17(1):
gmr16039870
DOI:
10.4238/gmr16039870
Plant Genetics   Research Article

Determination of the number of harvests to select elite sugarcane genotypes in NE Brazil

Authors: J.A. Dutra Filho, T.C. Junior, D. E. Simoes Neto, L. S. Souto, Romulo Gil de Luna A.S. Souza

Sixty-eight sugarcane genotypes were evaluated to determine the number of harvests required to select new genotypes in the sugarcane belt in the state of Pernambuco, northeast Brazil. Using a random block design, the following parameters were evaluated: (i) polarizable sugars (POL) per hectare, in metric tons (TPH); (ii) culm .. Read More»

Genet. Mol. Res. 17(1):
gmr16039869
DOI:
10.4238/gmr16039869