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Gene

Plant Genetics   Research Article

Genetic diversity between and within half-sib families of Brazil nut tree (Bertholletia excelsa Bonpl.) originating from native forest of the Brazilian Amazon

Authors: L.D. Giustina, A.B. Baldoni, F.D. Tardin, F.S. Gregolin, H. Tonini, L.G. Neves, L.P. Ribeiro, P.E. Teodoro

Brazil nut tree is a species of economic importance for the Amazon region, known for the commercialization of its almonds. The objective of this work was to study the genetic diversity among half-sib progenies from different Brazil nut trees present in native forest in the municipality of Itaúba, MT, belonging to the Br.. Read More»

Genet. Mol. Res. 16(4):
gmr16039839
DOI:
10.4238/gmr16039839
Plant Genetics   Research Article

Phenotypic, genotypic, and environmental correlations between characters in onion segregate populations obtained under different generations

Authors: D.L.M. Machado, J. A. de Freitas, J.M.Q. Luz, G. M. Maciel, A.P.O. Nogueira and E. di Camillo

Onion (Allium cepa L.) is the third most valuable vegetable crop worldwide and the third most produced in Brazil. The knowledge of the nature and the value of the relationship between the traits of interest is very important, since it is possible to select a main trait, with low heritability or difficult measurement, obtaining.. Read More»

Genet. Mol. Res. 16(4):
gmr16039838
DOI:
10.4238/gmr16039838
Human Genetics   Research Article

Protein Z gene variants and risk of Idiopathic Recurrent Pregnancy Loss in Saudi Arabian women

Authors: Walid Zammiti, Sarra Said, Amani Shaman, Faisel Mohammed Abu-Duhier

Background: Protein Z (PZ) is a vitamin K-dependent plasma glycoprotein, it plays a key role in the physiologic inhibition of coagulation by acting as a cofactor in the inactivation of factor Xa. The relationship between PZ gene polymorphisms and pregnancy loss is controversial. To address this, we investigate the association .. Read More»

Genet. Mol. Res. 16(4):
gmr16039834
DOI:
10.4238/gmr16039834
Plant Genetics   Research Article

Differential expression of dormancy-Associated genes in fastigiata and hypogaea peanut

Authors: M.F.C. Silva, C.R.C. Silva, L.M. Lima, JPC Ramos, and R.C. Santos

Seed dormancy is a temporary replacement state observed in some higher plants, which prevents germination under unfavorable conditions. In several species, dormancy process is triggered by hormonal factors, initiated by ABA and precursor enzymes. In this work, we investigated the relationship between dormancy and the expressio.. Read More»

Genet. Mol. Res. 16(4):
gmr16039820
DOI:
10.4238/gmr16039820
Human Genetics   Research Article

DNA methylation profile of the DKK2 gene as a biomarker in patients with colorectal cancer

Authors: T.D. Silva, A.V. Felipe, V.M. Vidigal, S.S. Saad, N.M. Forones

Purpose: Epigenetic changes can be detected in precancerous lesions, suggesting that may be involved in the early stages of carcinogenesis. The methylation of specifics genes has been correlated with the outcome of many different types of cancers. This study compared the levels of DNA methylation between normal and tumor tissu.. Read More»

Genet. Mol. Res. 16(4):
gmr16039816
DOI:
10.4238/gmr16039816
Human Genetics   Research Article

AluYb8 insertion in the WNK1 gene is not associated with hypertension in a Russian Caucasian population

Authors: Elmira Akhmedova, Svetlana Y. Nikulina, Alla B. Salmina, Anna Chernova, Marina Bazanova, Anna Ohapkina, Aleksey Semenchukov, Paolo E. Maltese, Elena Manara and Matteo Bertelli

WNK1 (With No-lysine Kinase 1), a serine-threonine kinase, regulates blood pressure by acting on various sodium transport-related ion channels. Several studies report a link between common variants of the WNK1 gene and hypertension. No data exists on Russian populations. Our aim was to evaluate the association between the WNK1.. Read More»

Genet. Mol. Res. 16(4):
gmr16039809
DOI:
10.4238/gmr16039809
Microbial Genetics   Research Article

Development of 21 novel polynucleotide microsatellite markers in a Clithon retropictum (Gastropoda: Neritidae), using next-generation sequencing

Authors: Young Se Hyun, Ha Yeun Song, Min-Seop Kim, Hye Suck An

The neritid species Clithon retropictum (Gastropoda), an oviparous snail, is distributed in freshwater and brackish water in southern Korea, south-east Japan, southern China and Taiwan. This species is listed as a class II endangered species in Korea because of its decreasing population size. It has led to an increase in the n.. Read More»

Genet. Mol. Res. 16(4):
gmr16039806
DOI:
10.4238/gmr16039806
Plant Genetics   Research Article

Iron excess in rice: from phenotypic changes to functional genomics of WRKY transcription factors

Authors: V.E. Viana, N. Marini, T. Finatto, I. Ezquer, C. Busanello, R.S. dos Santos, C. Pegoraro, L. Colombo and A. Costa de Oliveira

Iron (Fe) is an essential microelement for all living organisms playing important roles in several metabolic reactions. Rice (Oryza sativa L.) is commonly cultivated in paddy fields, where Fe goes through a reduction reaction from Fe3+ to Fe2+. Since Fe2+ is more soluble, it can reach toxic levels inside plant cells, constitut.. Read More»

Genet. Mol. Res. 16(3):
gmr16039694
DOI:
10.4238/gmr16039694
Human Genetics   Research Article

Assessment of the rs4340 ACE gene polymorphism in acute coronary syndrome in a Western Mexican population

Authors: A. Valdez-Haro, Y. Valle, E. Valdes-Alvarado, F. Casillas-Mu�±oz, J.F. Mu�±oz-Valle, G.L. Reynoso-Villalpando, H.E. Flores-Salinas and J.R. Padilla-Guti�©rrez

Acute coronary syndrome (ACS) is considered one of the main causes of death worldwide. Contradictory findings concerning the impact of the angiotensin-converting enzyme (ACE) gene on cardiovascular diseases have been reported. Previous conclusions point out that the variability in results depends on ethnicity and genetic polym.. Read More»

Genet. Mol. Res. 16(3):
gmr16039779
DOI:
10.4238/gmr16039779
Plant Genetics   Research Article

Structure and genetic diversity of Anacardium humile (Anacardiaceae): a tropical shrub

Authors: L.G. Cota, P.A. Moreira, M.M. Brand�£o, V.A. Royo, A.F. Melo Junior, E.V. Menezes and D.A. Oliveira

Anacardium humile Saint Hilaire is a tropical shrub native to the Cerrado biome. It is a fruiting species with biological, medicinal, and socioeconomic significance. Thus, knowing how the genetic variability of natural populations is organized allows for the establishment of strategies for conservation and the sustainable use .. Read More»

Genet. Mol. Res. 16(3):
gmr16039778
DOI:
10.4238/gmr16039778