Genetics
Isolation and characterization of polymorphic microsatellite loci from the invasive plant Solidago canadensis (Asteraceae)
Authors: S.-Y. Zhao, S.-G. Sun, Y.-H. Guo, J.-M. Chen and Q.-F. Wang
Solidago canadensis, a clonal herb originally from North America (common name: Canada goldenrod), is an invasive species in many countries. We developed microsatellite primers for this species. Eleven polymorphic loci were generated and primers were designed. Polymorphism of these 11 loci was assessed in 35 plants from two populations (Wuhan and Shanghai).. Read More»
- Genet. Mol. Res. 11(1):
- 2012.February.17.4
- DOI:
- 10.4238/2012.February.17.4
Cytogenetics and morphology of two tortoise species of the genus Chelonoidis (Fitzinger, 1835) (Testudines)
Authors: T.L. Silva
The reptiles were reduced in number of species since the time that they ruled the earth until today. The tortoises have been poorly studied, particularly their morphological and cytogenetic features. We examined the species Chelonoidis carbonaria and C. denticulata, terrestrial tortoises representative of two contrasting biome.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2ta034
- DOI:
- 10.4238/vol10-2ta034
Genetic analysis of 30 InDel markers for forensic use in five different Chinese populations
Authors: C.T. Li, S.H. Zhang and S.M. Zhao
Allele frequencies of 30 insertion/deletion polymorphism (InDel) markers previously selected and validated for forensic purposes were assessed in 419 unrelated individuals originating from five different populations of P.R. China, including Chinese Han, Chinese Hui, Uighur, Mongolians, and Tibetans. Hardy-Weinberg equilibrium .. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1082
- DOI:
- 10.4238/vol10-2gmr1082
Building the SeqChromMM Markov property atlas of the human genome by analyzing the 200-bp units of the 15 different chromatin regions of ENCODE
Authors: K.-E. Lee and H.-S. Park
We analyzed the publicly available ChromHMM BED files of the ENCODE project and tested the Markov properties of the different chromatin states in the human genome. Nucleotide frequency profiles of regional chromatin segmentations were analyzed, and Markov chains were built to detect Markov properties in the chromatin states of different ChromHMM regions. .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038992
- DOI:
- 10.4238/gmr.15038992
Fragmentation effects and genetic diversity of the key semidecidual forest species Metrodorea nigra in Southwestern Brazil
Authors: R.M. Moraes Filho, F. Bonif�¡cio-Anacleto and A.L. Alzate-Marin
Studies of genetic diversity in plant species present in the remaining fragments of the Atlantic Forest are very important for understanding their resilience to such a degraded ecosystem. We analyzed the genetic diversity of 3 populations of the high-density understory species Metrodorea nigra St. Hill. (Rutaceae) located in forest remnants in the region .. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.15.15
- DOI:
- http://dx.doi.org/10.4238/2015.April.15.15
Using Markov chains of nucleotide sequences as a possible precursor to predict functional roles of human genome: a case study on inactive chromatin regions
Authors: K.-E. Lee, E.-J. Lee, and H.-S. Park
Recent advances in computational epigenetics have provided new opportunities to evaluate n-gram probabilistic language models. In this paper, we describe a systematic genome-wide approach for predicting functional roles in inactive chromatin regions by using a sequence-based Markovian chromatin map of the human genome. We demonstrate that Markov chains of.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15039004
- DOI:
- 10.4238/gmr.15039004
Genetic variation in the parasympathetic signaling pathway in patients with reflex syncope
Authors: H.N. Holmegard, M. Benn, J. Mehlsen and S. Hauns�¸
Reflex syncope is defined by a self-terminating transient loss of consciousness associated with an exaggerated response of the vagal reflexes upon orthostatic challenges. A hereditary component has previously been suggested. We hypothesized that variations in genes encoding proteins mediating the vagal signaling in the heart may be involved in reflex sync.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.January.30.6
- DOI:
- 10.4238/2013.January.30.6
Prevalence of CYP2C8 polymorphisms in a North Indian population
Authors: S. Minhas, N. Setia, S. Pandita, R. Saxena, I.C. Verma and S. Aggarwal
CYP2C8 is an important member of the cytochrome P450 family of enzymes; it affects the activity of various drugs used in routine clinical practice, including amiodarone, chloroquine, amodiaquine, and repaglinide, as well as endogenous compounds, such as arachidonic acid and retonic acid. It is also the main enzyme involved in the metabolism of the widely .. Read More»
- Genet. Mol. Res. 12(3):
- 2013.July.8.7
- DOI:
- 10.4238/2013.July.8.7
Cytogenetic characteristics of patients with signs and symptoms of myelodysplastic syndromes in the State of Par�¡, Brazil
Authors: Giovanny RebouÃ?§as Pinto, David James Overal, Leopoldo Silva de Moraes, Ana VirgÃ?Ânia Van Den Berg, JosÃ?© Alexandre Rodrigues Lemos, MarÃ?Âlia de Arruda Cardoso Smith and Rommel RodrÃ?Âguez Burbano
The myelodysplastic syndromes (MDS) are clonal hematopoietic diseases characterized by medullary dysplasia, cytopenias, and frequent evolution to acute myeloid leukemia. In 1982, the French- American-British (FAB) group proposed a classification for the MDS, based on morphological characteristics of peripheral blood and of the.. Read More»
- Genet. Mol. Res. 4(1):
Distribution of CXCR2 +1208 T/C gene polymorphisms in relation to opportunistic infections among HIV-infected patients in Limpopo Province, South Africa
Authors: A. Samie, G.A. Dzhivhuho and T.C. Nangammbi
Interleukin 8 (IL-8) is a chemokine produced by macrophages and other cell types, including epithelial cells, and its receptor is CXCR2. IL-8 plays an important role in the initiation and amplification of inflammatory diseases, including opportunistic infections. With the advent of human immunodeficiency virus (HIV) and acquir.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.12.13
- DOI:
- 10.4238/2014.September.12.13