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Genetics

Plant Genetics   Research Article

Genetic improvement of plant architecture in the common bean

Authors: V.M.P. Silva, J.A.N. Menezes J�ºnior, P.C.S. Carneiro2, J.E.S. Carneiro and C.D. Cruz

Knowledge of genetic control of plant architecture in the common bean can help breeders define the most adequate breeding strategy to optimize gains. We examined genetic control of plant architecture in the common bean by means of partial diallel crosses. Fourteen bean lines were crossed under a partial diallel scheme, in which group 1 was composed of 8 e.. Read More»

Genet. Mol. Res. 12(3):
2013.January.30.8
DOI:
10.4238/2013.January.30.8
Human Genetics   Research Article

Interethnic variation of the MMP-9 microsatellite in Amerindian and Mexican Mestizo populations: considerations for genetic association studies

Authors: R. Camacho-Mejorado, G. Noris, C. Santana, J.J. Maga�±a,A. Majluf-Cruz, J. Arellano-Galindo, A. De la Pe�±a, J. Hern�¡ndez-Ju�¡rez, E.S. Calder�³n-Aranda, M.A. Meraz-R�­os and R. G�³mez

We studied the interethnic variation of the MMP-9 microsatellite in the Mestizo and Amerindian populations using blood samples collected from 435 healthy unrelated individuals from the Central Valley of Mexico. DNA samples were genotyped using the -90 (CA)12-27 repeat near the MMP transcriptional start site using capillary ele.. Read More»

Genet. Mol. Res. 14(1):
2015.March.31.24
DOI:
10.4238/2015.March.31.24
Plant Genetics   Research Article

Genetic, embryonic and anatomical study of an interspecific cassava hybrid

Authors: N.M.A. Nassar, D.Y. Hashimoto and D.G. Ribeiro

A molecular, anatomical and cytogenetic study of an interspecific hybrid between Manihot esculenta (cassava) and the wild species M. oligantha was carried out. Cytogenetics revealed relatively complete chromosome pairing and high viability of the pollen grains. Ovule structure examined by the clearing method showed polyembryon.. Read More»

Genet. Mol. Res. 9(1):
vol9-1gmr746
DOI:
10.4238/vol9-1gmr746
Microbial Genetics   Research Article

Lack of an effect of CYP3A4 and MDR1 gene polymorphisms on colchicine pharmacogenetics in the treatment of Familial Mediterranean fever

Authors: D. Dogruer, E. Tug, C. Bes and M. Soy

The P-gp/MDR1 multidrug transporter mediates detoxification of numerous drugs, including colchicine, and CYP3A4 is key to the biotransformation of colchicine. We investigated the effects of CYP3A4 and P-gp/MDR1 polymorphisms on bioavailability of colchicine in patients with Familial Mediterranean fever (FMF). Forty-eight Turkish patients with FMF treated .. Read More»

Genet. Mol. Res. 12(3):
2013.January.24.2
DOI:
10.4238/2013.January.24.2
Human Genetics   Research Article

Description of the pre-reductional sex chromosome during male meiosis of Pachylis laticornis (Heteroptera: Coreidae)

Authors: C.A. Banho, K.C.C. Alevi, L.L.V. Pereira, T.S. Souza-Firmino and M.M. Itoyama

In Heteroptera, the division of sex chromosomes is well defined as post-reductional for most of species, i.e., the first meiotic division is equational and the second is reductional. However, in some species pre-reductional division has been observed, whereby the first meiotic division is reductional and the second is equation.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027592
DOI:
10.4238/gmr.15027592
Human Genetics   Research Article

Genetic structure of the threatened Hopea chinensis in the Quang Ninh Province, Vietnam

Authors: N.T.P. Trang and L. Triest

Hopea chinensis Hand-Mazz (synonym H. hongayensis Tardieu), is a wind and insect pollinated species. It is a threatened species known only from two locations: Quang Ninh (Vietnam) and Guangxi (China). As an endemic species, it is worth preserving both for dipterocarp biodiversity, as well as for its medicinal use and economic .. Read More»

Genet. Mol. Res. 15(2):
gmr.15028103
DOI:
10.4238/gmr.15028103
Human Genetics   Research Article

Relationship between the polymorphisms in KCNQ1 and type 2 diabetes in Chinese Kazakh population

Authors: L.J. Cui, X.Y. Chang, L.Y. Zhu, G. Feng, T. Zhou, C.X. Zhang, K.Y. Chong and K. Sun

Recently genome-wide association studies on East Asian populations reported an association between diabetes and several single nucleotide polymorphisms (SNPs) in a 40-kb linkage disequilibrium block in intron 15 of KCNQ1. However, the association between KCNQ1 variants and type 2 diabetes mellitus (T2DM) in Chinese Kazakh popu.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027503
DOI:
10.4238/gmr.15027503
Microbial Genetics   Research Article

Association between survivin gene promoter -31G/C and -644C/T polymorphisms and non-small cell lung cancer

Authors: E. Aynaci, E. Coskunpinar, A. Eren, O. Kum, Y.M. Oltulu, N. Akkaya, A. Turna, I. Yaylim and P. Yildiz

Lung cancer is the most common cancer worldwide. Survivin is one of the first reported inhibitors of apoptosis proteins, which is an important family of proteins that regulate apoptosis. The survivin gene is located on human chromosome 17q25, which is composed of 142 amino acids. A common polymorphism of the survivin gene promoter -31G/C has been shown to.. Read More»

Genet. Mol. Res. 12(3):
2013.February.28.9
DOI:
10.4238/2013.February.28.9
Human Genetics   Research Article

Karyotype structure of Hypostomus cf. plecostomus (Linnaeus, 1758) from Tapaj�³s River basin, Southern Amazon: occurrence of sex chromosomes (ZZ/ZW) and their evolutionary implications

Authors: L.C. Oliveira, M.O. Ribeiro, E.S. Dutra, C.H. Zawadzki, A.L.B. Portela-Castro5 and I.C. Martins-Santos

Hypostomus is a group of fish with numerical and structural karyotypic variability. Among them, only six species, three of which belong to the Amazon basin, show a sex chromosome. In this study, we present the karyotype structure of Hypostomus cf. plecostomus from the Teles Pires river basin in the municipality of Alta Floresta, MT. The species has 2n = 6.. Read More»

Genet. Mol. Res. 14(2):
2015.June.18.5
DOI:
10.4238/2015.June.18.5
Medical Genetics   Research Article

Nucleolar-persistence phenomenon during spermatogenesis in genus Meccus (Hemiptera, Triatominae)

Authors: F.F. Madeira, A.A.C. Lima, J.A. Rosa, M.T.V. Azeredo-Oliveira and K.C.C. Alevi

The Triatominae subfamily consists of 150 species in 18 genera, grouped into six tribes. In cytogenetics, triatomines are important biological models because they have holocentric chromosomes and nucleolar persistence in meiosis. The phenomenon of nucleolar persistence has been described for 23 species of triatomine in three g.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017427
DOI:
10.4238/gmr.15017427