Genetics
Cytogenetic analysis of Triatoma pseudomaculata CorrÃ?ªa and EspÃ?Ânola, 1964 (Hemiptera, Triatominae) from different Brazilian states
Authors: C.H.L. Imperador, K.C.C. Alevi, J. Oliveira, J.A. Rosa and M.T.V. Azeredo-Oliveira
Triatoma maculata and T. pseudomaculata are allopatric; however, it is believed that T. maculata was introduced into the Brazilian northeast by passive transportation of the nymphs between the feathers of migratory birds, followed by the speciation of T. pseudomaculata. T. pseudomaculata is the second most epidemiologically important species in the northe.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15016937
- DOI:
- 10.4238/gmr.15016937
Correlation between natriuretic peptide receptor C (NPR3) gene polymorphisms and hypertension in the Dai people of China
Authors: H. Sun, Z.Q. Yang, S.Y. Liu, L. Yu, K. Huang, K.Q. Lin, J.Y. Chu and X.Q. Huang
Hypertension affects one-fifth of the world population. Genome-wide association studies (GWAS) have identified several single nucleotide polymorphisms (SNPs) that correlated with hypertension in large samples. However, the genetic mutations leading to hypertension might differ among various populations, as they have different origins and are subjected to .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.3.2
- DOI:
- 10.4238/2015.August.3.2
Development and characterization of microsatellite markers for Ulmus chenmoui (Ulmaceae), an endangered tree endemic to eastern China
Authors: Q.F. Geng, J. He, J. Yang, E. Shi, D.B. Wang, W.X. Xu,N. Jeelani Z.S. Wang and H. Liu
Ulmus chenmoui (Ulmaceae) is an endangered tree found on Langya Mountain, eastern China. To better understand the population genetics of U. chenmoui and conserve the species, we developed microsatellite markers. Using a suppression-polymerase chain reaction technique, 74 compound microsatellite primer pairs were designed. Twel.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027985
- DOI:
- 10.4238/gmr.15027985
S-adenosylmethionine, a methyl donor, up regulates tissue inhibitor of metalloproteinase-2 in colorectal cancer
Authors: Z. Hussain, M.I. Khan, M. Shahid and F.N. Almajhdi
DNA methylation is a fundamental epigenetic mechanism in regulating the expression of genes controlling crucial cell functions in cancer development. Gene silencing via CpG island methylation/demethylation in the promoter region is one of the mechanisms by which different genes are inactivated/activated in human cancers. Tissue inhibitor of metalloprotein.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.10.6
- DOI:
- 10.4238/2013.April.10.6
Relationship between genetic polymorphisms of DNA ligase 1 and non-small cell lung cancer susceptibility and radiosensitivity
Authors: H. Tian, X. He, L. Yin, W.J. Guo, Y.Y. Xia and Z.X. Jiang
The aim of this study was to examine the relationship between genetic polymorphisms in DNA ligase 1 (LIG1) and nonsmall cell lung cancer (NSCLC) susceptibility and radiosensitivity in a Chinese population. This was a case-control study that included 352 NSCLC patients and 448 healthy controls. Polymerase chain reactionrestriction fragment length polymorph.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.26.14
- DOI:
- 10.4238/2015.June.26.14
Distribution of constitutive heterochromatin in Triatoma melanocephala (Hemiptera, Triatominae)
Authors: K.C.C. Alevi, J.A. Rosa and M.T.V. Azeredo-Oliveira
In principle, Triatoma melanocephala was included in the Brasiliensis subcomplex on the basis of morphological parameters and geographical layout, since there were no other relevant data available in the literature. On the basis of karyotype, it has been proposed to exclude T. melanocephala, as well as of .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.29.2
- DOI:
- 10.4238/2014.September.29.2
Selection in sugarcane based on inbreeding depression
Authors: A.A.C. de Azeredo, L.L. Bhering, B.P. Brasileiro, C.D. Cruz and M.H.P. Barbosa
This study aimed to evaluate the gene action associated with yield-related traits, including mean stalk weight (MSW), tons of sugarcane per hectare (TCH), and fiber content (FIB) in sugarcane. Moreover, the viability of individual reciprocal recurrent selection (RRSI-S1) was verified, and the effect of inbreeding depression on.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027965
- DOI:
- 10.4238/gmr.15027965
Interaction between ALOX5AP-SG13S114A/T and COX-2-765G/C increases susceptibility to cerebral infarction in a Chinese population
Authors: X.Y. Yi, Q. Zhou, J. Lin, L.F. Chi and W.Z. Chi
We made a case-control study to investigate a possible association between ALOX5AP-SG13S114A/T, COX-2-765G/C, and COX-1-50C/T polymorphisms with cerebral infarction in a Chinese population. A total of 411 cases with cerebral infarction were included; 411 controls matched for age, gender, and risk factors were also selected. The ALOX5AP-SG13S114A/T (rs1050.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.May.14.6
- DOI:
- 10.4238/2013.May.14.6
Development and characterization of microsatellite loci for genetic studies of the sugarcane borer, Diatraea saccharalis (Lepidoptera: Crambidae)
Authors: V.A.C. Pavinato, K.L. Silva-Brand�£o, M. Monteiro, M.I. Zucchi, J.B. Pinheiro, F.L.F. Dias and C. Omoto
We present polymorphic microsatellite markers isolated for genetic studies of the sugarcane borer, Diatraea saccharalis (Fabricius). We isolated 16 microsatellite loci through an enriched genomic library protocol. After characterization, 12 markers showed polymorphic information expressed in the observed number of alleles (ranging from 2 to 7; 5 on averag.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.May.14.3
- DOI:
- 10.4238/2013.May.14.3
Genetic differentiation in Aspidosperma polyneuron (Apocynaceae) over a short geographic distance as assessed by AFLP markers
Authors: J.O. Damasceno, E.A. Ruas, L.A. Rodrigues, C.F. Ruas, E. Bianchini, J.A. Pimenta3 and P.M. Ruas
Studies on intraspecific variation can contribute to the development of conservation strategies by identifying units of conservation for threatened species. Aspidosperma polyneuron is a tropical tree of seasonal semideciduous forests that is currently endangered and protected because it has been heavily logged for lumber, alth.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1126
- DOI:
- 10.4238/vol10-2gmr1126