Genetics
Common genetic risk factors of venous thromboembolism in Western and Asian populations
Authors: S.S. Huang1*, Y. Liu2*, Z.C. Jing3, X.J. Wang3 and Y.M. Mao1
Venous thromboembolism (VTE) is a multifactorial disorder involving both acquired and genetic risk factors. The common genetic factors in Western populations have been studied and reported for several decades, while studies on Asian populations are relatively scarce. Evidence suggests that the prevalence and genetic risk factors of VTE vary significantly .. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017644
- DOI:
- 10.4238/gmr.15017644
Cytogenetic findings in an epithelioid sarcoma with angiomatoid features. A case report
Authors: M.S. Brassesco, E.T. Valera, A.M. Castro-Gamero, D.A. Moreno,T.P. Silveira, B.M. Mori, E.E. Engel4, C.A. Scrideli and L.G. Tone
Epithelioid sarcoma is a rare, aggressive soft tissue tumor of unknown histogenesis showing predominantly epithelioid cytomorphology. We conducted a conventional and molecular cytogenetic study of a 27-year-old male with epithelioid sarcoma with angiomatoid features. Cytogenetic analysis of epithelioid sarcoma metaphase spread.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr656
- DOI:
- 10.4238/vol8-4gmr656
Genome-wide identification and characterization of simple sequence repeat loci in grape phylloxera, Daktulosphaira vitifoliae
Authors: H. Lin, M.S. Islam and D.W. Ramming
A genome-wide sequence search was conducted to identify simple sequence repeat (SSR) loci in phylloxera, Daktulosphaira vitifoliae, a major grape pest throughout the world. Collectively, 1524 SSR loci containing mono-, di-, tri-, tetra-, penta-, and hexanucleotide motifs were identified. Among them, trinucleotide repeats were .. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.15.11
- DOI:
- 10.4238/2012.May.15.11
Population genetic structure in Phyla scaberrima from Mexico and Colombia assessed by AFLP markers and implications for conservation
Authors: L.G. Androcioli, E.A. Ruas, L.A. Rodrigues, C.F. Ruas , H.E.R. Perilla, P.M. Ruas
Phyla scaberrima (Verbenaceae) is a herbaceous perennial species that is distributed from Mexico (center of origin) to Colombia, growing in forest and swamp edges or grasslands from sea level up to an altitude of 1800 m. The chemical properties and uses in popular medicine have drastically affected the population siz.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.21
- DOI:
- 10.4238/2015.December.1.21
Genetic diversity and differentiation in natural populations of Arapaima gigas from lower Amazon revealed by microsatellites
Authors: P.F. Fazzi-Gomes, N. Melo, G. Palheta, S. Guerreiro, M. Amador, A.K. Ribeiro-dos-Santos, S. Santos and I. Hamoy
Genetic variability is one of the important criteria for species conservation decisions. This study aimed to analyze the genetic diversity and the population differentiation of two natural populations of Arapaima gigas, a species with a long history of being commercially exploited. We collected 87 samples of A. gigas from Gran.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019552
- DOI:
- 10.4238/gmr16019552
Isolation and characterization of 8 microsatellite loci from Chrysophyllum gonocarpum (Sapotaceae)
Authors: Isolation and characterization of 8 microsatellite loci from Chrysophyllum gonocarpum (Sapotaceae)
Chrysophyllum gonocarpum is a tropical tree species that is very important in the recovery of heterogeneous forests and of degraded areas of permanent preservation. We identified microsatellite loci for C. gonocarpum to assess the genetic variability and the patterns of the population structure of the species. We isolated 8 microsatellite primers by using CT.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.8.6
- DOI:
- 10.4238/2013.February.8.6
Genetic control and transgressive segregation of zinc, iron, potassium, phosphorus, calcium, and sodium accumulation in cowpea (Vigna unguiculata) seeds
Authors: C.A. Fernandes Santos1 and L.S. Boiteux2
Cowpea crop, through combining a range of essential minerals with high quality proteins, plays an important role in providing nutritional security to human population living in semi-arid regions. Studies on genetics of biofortification with essential minerals are still quite scarce, and the major objective of the present study was to provide genetic informat.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.16.10
- DOI:
- 10.4238/2015.January.16.10
Genetic variability of CYP3A4 in a heterogeneous Brazilian population from Maranh�£o
Authors: S.C. Moutinho Monteiro1, I.H. de Sousa1, I.K. Pereira Belfort1,J.D. Nunes1, B.A. Sousa Penha1, M. dos Santos2, I. Drumond Louro3 and I.D.C. Guerreiro da Silva4
Inter-individual variability in drug metabolism may result in adverse drug responses. Pharmacogenetic studies have shown that polymorphisms in drug metabolizing enzymes may contribute to this variability. Among these enzymes, CYP3A4 is responsible for metabolizing over 50% of the clinically used drugs. The Brazilian population is composed of people with N.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017275
- DOI:
- 10.4238/gmr.15017275
Comparison of DNA extraction methods for polymerase chain reaction amplification of guanaco (Lama guanicoe) fecal DNA samples
Authors: M.I. Espinosa, A. Bertin, F.A. Squeo, A. Cort�©s and N. Gouin
Feces-based population genetic studies have become increasingly popular. However, polymerase chain reaction (PCR) amplification rates from fecal material vary depending on the species, populations, loci, and extraction protocols. Here, we assessed the PCR amplification success of three microsatellite markers and a segment of the mitochondrial control regi.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.23.13
- DOI:
- 10.4238/2015.January.23.13
Isolation and characterization of microsatellite loci for Cunninghamia lanceolata (Lamb.) Hook
Authors: Y.X. Li, Z.S. Wang, J.K. Sui, Y.F. Zeng, A.G. Duan and J.G. Zhang
As a result of human activities, wild populations of Cunninghamia lanceolata (Cupressaceae) have sharply declined in recent years. The development and implementation of a valid conservation strategy require a clear understanding of the genetic makeup of this species. Eleven polymorphic microsatellite loci were isolated and characterized from samples of 52.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.23.19
- DOI:
- 10.4238/2015.January.23.19