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Genetics

Cytogenomics   Research Article

Development and characterization of DNA microsatellite primers for buriti (Mauritia flexuosa L.f.)Development and characterization of DNA microsatellite primers for buriti (Mauritia flexuosa L.f.)

Authors: Development and characterization of DNA microsatellite primers for buriti (Mauritia flexuosa L.f.)

Mauritia flexuosa L. (Arecaceae) is a palm tree species known as buriti that occurs in the Cerrado biome. It is characteristic of the vereda, a typical ecosystem of central Brazil. In this phytophysiognomy, M. flexuosa and other groups of arboreal-herbaceous species develop in open fields with very humid soils. M. flexuosa can be found in forest borders a.. Read More»

Genet. Mol. Res. 11(4):
2012.September.17.6
DOI:
10.4238/2012.September.17.6
Plant Genetics   Research Article

Implications of the progeny x environment interaction in selection index involving characteristics of the common bean

Authors: L.K. Lima M.A.P. Ramalho A.F.B. Abreu

Breeders normally select simultaneously for several traits in various environments. We investigated the effects of the progeny x environment interaction on success in selection for several traits. The population used was obtained from a cross between the CVIII-85-11 line, which has a semi-erect to prostrate plant architecture and a cream with brown streak.. Read More»

Genet. Mol. Res. 11(4):
2012.September.19.5
DOI:
10.4238/2012.September.19.5
Animal Genetics   Research Article

Single primer-based DNA amplification as a suitable and low-cost tool for assessing genetic diversity in mangrove crabs

Authors: F.B. Britto, D.S.F. Mendes, M. Ogawa, I.H.A. Cintra and F.M. Diniz

We used single primer-based DNA markers to assess genetic variability of the mangrove crab, Ucides cordatus, collected from four different localities from Pará to Santa Catarina States in Brazil (almost 5000 km distant). Five primers were chosen based on the consistency of the amplified bands and the polymorphism of eac.. Read More»

Genet. Mol. Res. 10(4):
2011.November.9.2
DOI:
10.4238/2011.November.9.2
Medical Genetics   Research Article

Novel NKX2-5 mutations responsible for congenital heart disease

Authors: J. Wang, X.Y. Liu and Y.Q. Yang

Congenital heart disease (CHD) is the most common birth defect and is the leading cause of infant morbidity and mortality resulting from birth defects. Increasing evidence demonstrates that genetic variation in the NKX2-5 gene, which encodes a homeobox-containing transcription factor crucial to cardiogenesis, is an important m.. Read More»

Genet. Mol. Res. 10(4):
2011.November.29.1
DOI:
10.4238/2011.November.29.1
Human Genetics   Research Article

Molecular and chromosomal mutations among children with B-lineage lymphoblastic leukemia in Brazilâ??s Federal District

Authors: D.R. Mesquita J.C. C?³rdoba ?.Q. Magalh?£es M.S. C?³rdoba J.R.C. Oliveira A. Gon?§alves I. Ferrari C. Martins-de-S?¡

Acute lymphoblastic leukemia (ALL) accounts for approximately 80% of all acute leukemias during childhood. Chromosomal anomalies resulting from gene fusion, which are frequent in leukemias, create hybrid transcripts, the great majority of which encode transcription factors. We analyzed 88 pediatric patients (median age 7.3 yea.. Read More»

Genet. Mol. Res. 8(1):
vol8-1gmr582
DOI:
10.4238/vol8-1gmr582
Microbial Genetics   Research Article

Karyotype and spermatogenesis in Triatoma lenti (Hemiptera: Triatominae), a potential Chagas vector

Authors: K.C.C. Alevi P.P. Mendon?§a M. Succi N.P. Pereira J.A. Rosa M.T.V. Azeredo-Oliveira

All species of Triatominae are susceptible to infection by Trypanosoma cruzi (Kinetoplastida: Trypanosomatidae) and consequently, potential insect vectors of Chagas disease. Currently, there are 140 known species of triatomine bugs, which can be grouped into specific species complexes. The species Triatoma lenti (Hemiptera: Triatominae) is found only in B.. Read More»

Genet. Mol. Res. 11(4):
2012.December.17.3
DOI:
10.4238/2012.December.17.3
Plant Genetics   Short communication

Isolation of microsatellite loci for Rhodiola alsia (Crassulaceae), an important ethno-medicinal herb endemic to the Qinghai-Tibetan plateau

Authors: F.Q. Zhang, S.Y. Lei, Q.B. Gao, G. Khan, R. Xing, H.L. Yang and S.L. Chen

Rhodiola alsia, which has been used widely in traditional Chinese medicine for a considerable time, grows on moist habitats at high altitude near the snow line. Microsatellite loci were developed for R. alsia to investigate its population genetics. In total, 17 polymorphic microsatellites were developed based on ESTs from the Illumina HiSeqTM 2000 platfor.. Read More»

Genet. Mol. Res. 14(2):
2015.May.18.18
DOI:
10.4238/2015.May.18.18
Plant Genetics   Research Article

Variable number of tandem repeat markers in the genome sequence of Mycosphaerella fijiensis, the causal agent of black leaf streak disease of banana (Musa spp)

Authors: S.A.L. Garcia*, T.A.J. Van der Lee*, C.F. Ferreira*, B. Te Lintel Hekkert, M.-F. Zapater, S.B. Goodwin, M. Guzm?¡n, G.H.J. Kema and M.T. Souza Jr.

We searched the genome of Mycosphaerella fijiensis for molecular markers that would allow population genetics analysis of this plant pathogen. M. fijiensis, the causal agent of banana leaf streak disease, also known as black Sigatoka, is the most devastating pathogen attacking bananas (Musa spp). Recently, the entire genome se.. Read More»

Genet. Mol. Res. 9(4):
vol9-4gmr934
DOI:
10.4238/vol9-4gmr934
Animal Genetics   Research Article

Introgression of genes for cotton leaf curl virus resistance and increased fiber strength from Gossypium stocksii into upland cotton (G. hirsutum)

Authors: W. Nazeer, S. Ahmad, K. Mahmood, A.L. Tipu, A. Mahmood, B. Zhou

Cotton leaf curl virus disease is a major hurdle for successful cotton production in Pakistan. There has been considerable economic loss due to this disease during the last decade. It would be desirable to have cotton varieties resistant to this disease. We explored the possibility of transferring virus resistant genes from th.. Read More»

Genet. Mol. Res. 13(1):
http://dx.doi.org/2014.February.21.2
DOI:
http://dx.doi.org/10.4238/2014.February.21.2
Human Genetics   Research Article

Association of CYP2C19*3 gene polymorphism with breast cancer in Chinese women

Authors: C.Q. Gan, X.Y. Wang, Y.D. Cao, W.X. Ye, H. Liu and Y.Y. Sun

Cytochrome P450 (CYP) 2C19 metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids, which significantly promote proliferation of cancer cells in vitro and in vivo. We looked for a possible association between human CYP2C19*3 gene polymorphism and breast cancer in the Chinese Han population. In a Chinese H.. Read More»

Genet. Mol. Res. 10(4):
2011.December.5.3
DOI:
10.4238/2011.December.5.3