Genotoxicity

Elevated micronucleus frequencies in patients with pleural plaque secondary to environmental exposure to asbestos

Authors: M. G�?¶vercin, A.G. Tomat�?±r, F. Evyapan, �?°. Acikbas, G. Co�?�?kun and B. Akdag

We examined genotoxic damage and frequency of micronuclei in people living in the Bekilli and Suller districts of Denizli city who had been diagnosed with pleural plaques as a result of environmental exposure to asbestos. Peripheral blood samples were obtained from 30 volunteer patients 59-86 years old who did not smoke or con.. Read More»

Genet. Mol. Res. 13(1):

2014.January.28.5

DOI:

10.4238/2014.January.28.5

Application of molecular markers to detect DNA damage caused by environmental pollutants in lichen species

Authors: D. Cansaran-Duman, E. Altunkaynak, A. Aslan, �?°. B�?¼y�?¼k and S. Aras

Pseudevernia furfuracea L. (Zopf), Peltigera praetextata (Flörke ex Sommerf.) Zopf, Lobaria pulmonaria (L.) Hoffm., and Usnea longissima Ach. lichen species were used as bioindicators to assess the genotoxicity of air pollutants. In the present study, we examined significant environmetal pollutants and investigate how changes may lead to damage in DN.. Read More»

Genet. Mol. Res. 14(2):

2015.May.4.23

DOI:

10.4238/2015.May.4.23

Evaluation of genotoxicity of Pseudevernia furfuracea (L.) Zopf by RAPD analysis

Authors: S. Aras, T. Beyazta�?�?, D. Cansaran-Duman and E. G�?¶k�?§e-G�?¼nd�?¼zer

We investigated the suitability and applicability of Pseudevernia furfuracea (L.) Zopf for environmental genotoxicity assessment. P. furfuracea lichen specimens were collected from 10 different Pinus species, in every 5 km, starting from around an iron-steel factory located in the central area of Karabük Province up to Ye.. Read More»

Genet. Mol. Res. 10(4):

2011.December.15.4

DOI:

10.4238/2011.December.15.4

Resistant starch: a functional food that prevents DNA damage and chemical carcinogenesis

Authors: S.D. Navarro, M.O. Mauro, J.R. Pesarini, F.M. Ogo and R.J. Oliveira

Resistant starch is formed from starch and its degradation products and is not digested or absorbed in the intestine; thus, it is characterized as a fiber. Because fiber intake is associated with the prevention of DNA damage and cancer, the potential antigenotoxic, antimutagenic, and anticarcinogenic capabilities of resistant starch from green banana flou.. Read More»

Genet. Mol. Res. 14(1):

2015.March.6.14

DOI:

10.4238/2015.March.6.14

In vitro assessment of the genotoxic and cytotoxic effects of boiled juice (tucupi) from Manihot esculenta Crantz roots

Authors: L.A. Cunha, T.C. Mota, P.C.S. Cardoso, D.D.F.�?. Alc�?¢ntara,R.M.R. Burbano, A.C. Guimar�?£es, A.S. Khayat, C.A.M. Rocha and M.O. Bahia

The population of Pará (a state in Brazil) has a very characteristic food culture, as a majority of the carbohydrates consumed are obtained from cassava (Manihot esculenta Crantz) derivatives. Tucupi is the boiled juice of cassava roots that plays a major role in the culinary footprint of Pará. Before boiling, th.. Read More»

Genet. Mol. Res. 15(4):

gmr.15048825

DOI:

10.4238/gmr.15048825

Induction of mitotic crossing-over in diploid strains of Aspergillus nidulans using low-dose X-rays

Authors: L.B. Stoll, F.C.A. Cremonesi, L.T.A. Pires, T.D. Zucchi andT.M.A.D. Zucchi4,

As a contribution towards detecting the genetic effects of low doses of genotoxic physical agents, this paper deals with the consequences of low-dose X-rays in the Aspergillus nidulans genome. The irradiation doses studied were those commonly used in dental clinics (1-5 cGy). Even very low doses promoted increased mitotic crossing-over frequencies in dipl.. Read More»

Genet. Mol. Res. 7(2):

vol7-2gmr414

DOI:

10.4238/vol7-2gmr414

Genotoxicity, cytotoxicity and toxicological evaluation of whole plant extracts of the medicinal plant Phyllanthus niruri (Phyllanthaceae)

Authors: G.A. Asare, K. Bugyei, A. Sittie, E.S. Yahaya, B. Gyan, S. Adjei, P. Addo, E.K. Wiredu, D.N. Adjei and A.K. Nyarko

Phyllanthus niruri is a medicinal plant (commonly known as stone breaker) found in the tropics and other parts of the world. It is known for its capacity to block the formation of calcium oxalate crystals and kidney stone formation in urolithiasis. This plant has been used to treat hyperglycemia, hypertension, pain, and mild c.. Read More»

Genet. Mol. Res. 11(1):

http://dx.doi.org/2012.January.13.3

DOI:

http://dx.doi.org/10.4238/2012.January.13.3

Contribution of Maistro et al. in Genetics and Molecular Research

Authors: J. Reichling, K. Kraft, R. Gome, O. Kelber and T. Wegener

Genet. Mol. Res. 10(2):

vol10-2gmr1445

DOI:

10.4238/vol10-2gmr1445

Assessment of genotoxic, cytotoxic, and protective effects of Salacia crassifolia (Mart. Ex. Schult.) G. Don. stem bark fractions in mice

Authors: C.C. Carneiro, C.R. Silva, A.C.S. Menezes, C.N. P�?©rez and L. Chen-Chen

Salacia crassifolia (Mart. Ex. Schult.) G. Don., popularly known in Brazil as “bacupari”, “cascudo”, and “saputá”, is a shrub of the Celastraceae family that is unique to the Brazilian Cerrado region. In folk medicine, this plant has been mainly used to treat skin cancer and gastric ulcers. In the present study, .. Read More»

Genet. Mol. Res. 12(3):

2013.July.3.1

DOI:

10.4238/2013.July.3.1

Antigenotoxic and antimutagenic potential of an annatto pigment (norbixin) against oxidative stress

Authors: Antonio C.T.S. J�?ºnior, L�?­dia M.B.O. Asad, Eduardo B. de Oliveira, Karla Kovary, Nasser R. Asad and Israel Felzenszwalb

Carotenoids are 40-carbon molecules with conjugated double bonds, making them particularly effective for quenching free radicals. They have always been believed to possess anticancer properties, which could be due to their antioxidant potential. Norbixin is an unusual dicarboxylic water-soluble carotenoid present as a componen.. Read More»

Genet. Mol. Res. 4(1):