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Genotoxicity

Microbial Genetics   Research Article

Can Spirulina maxima reduce the mutagenic potential of sibutramine?

Authors: R.P. Araldi, N.P. Santos, T.B. Mendes, L.B. Carvalho, E.T. Ito, P.L. de-S�¡-J�ºnior and EB Souza

The worldwide obesity pandemic requires the use of anti-obesity drugs. Sibutramine is an anti-obesity drug that has been used worldwide but is indiscriminately consumed in Brazil. Several studies have demonstrated that sibutramine promotes weight loss and weight maintenance, but several side effects have been associated with its systematic consumption. Fo.. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.33
DOI:
10.4238/2015.December.23.33
Human Genetics   Research Article

Occupational genotoxicity risk evaluation through the comet assay and the micronucleus test

Authors: M.G. Martino-Roth, J. Vi�©gas, D.M. Roth

The micronucleus (MN) test and the alkaline single cell gel or comet assay were applied to exfoliated cells of the buccal mucous in order to evaluate the genotoxic risk associated with occupational exposure of 10 storage battery renovation workers, and 10 car painters, with age matched controls, in Pelotas, RS, in southern Brazil. In the MN test, 2000 exf.. Read More»

Genet. Mol. Res. 2(4):