Glucose
AtBTH1, a BTB domain-containing protein, influences sugar-responsive germination and seedling growth in Arabidopsis
Authors: J.E. Hwang, Y.J. Kim, M.H. Shin, J. Park, W. Choi, D.J. Yun and H.C. Park
Sugars function as signal molecules that regulate gene expression, growth, and development in plants, animals, and yeasts. As a contribution to understanding the molecular mechanisms of sugar responses, we identified and characterized an Arabidopsis thaliana BTB domain-containing protein of the H subfamily 1 (designated AtBTH1). The relative expression le.. Read More»
- Genet. Mol. Res. 17(4):
- http://dx.doi.org/gmr16039932
- DOI:
- http://dx.doi.org/10.4238/gmr16039932
Improvement of Exercise Intervention on Vascular Endothelial Functions during Prediabetes Mellitus
Authors: Shaobing Wang, Zhenghong Zhang, Yiping Liu, Zhengchao Wang
Prediabetes is considered to be an at a risk state, with an annualized 5-10% conversion rate of diabetes and the similiar proportion converting back to normoglycaemia. The global incidence of prediabetes is increasing and will reach to 471 million patients in 2030. The elevation of blood sugar is a continuum and hence prediabe.. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039830
- DOI:
- 10.4238/gmr16039830
Interleukin-18 (rs187238) and glucose transporter 4 (rs5435) polymorphisms in Euro-Brazilians with type 1 diabetes
Authors: Y. Al-Lahham, A.K.B. Mendes, E.M. Souza, D. Alberton, F.G.M. Rego, G. Valdameri and G. Picheth
Type 1 diabetes (T1D) is an autoimmune disease with a strong genetic component that has been associated with several genetic loci. Interleukin 18 (IL-18) is a potent proinflammatory cytokine, which is involved in the innate and adaptive immune responses, and in the pathogenesis of various diseases including T1D. Glucose transp.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039755
- DOI:
- 10.4238/gmr16039755
Characterization of glucose-tolerant ?²-glucosidases used in biofuel production under the bioinformatics perspective: a systematic review
Authors: D.C.B. Mariano, C. Leite, L.H.S. Santos, L.F. Marins, K.S. Machado, A.V. Werhli, L.H.F. Lima and R.C. de Melo-Minardi
β-glucosidases are enzymes that catalyze the hydrolysis of oligosaccharides and disaccharides, such as cellobiose. These enzymes play a key role in cellulose degrading, such as alleviating product inhibition of cellulases. Consequently, they have been considered essential for the biofuel industry. However, the majority of.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039740
- DOI:
- 10.4238/gmr16039740
Effects of glucose sensing/signaling on oxidative stress response in glucose repression mutants of Schizosaccharomyces pombe
Authors: B. Palabiyik, F. Jafari Ghods and E. Onay Ucar
The resistant to glucose repression mutants of Schizosaccharomyces pombe (ird5, ird13, and ird14) have a high tolerance to oxidative stress induced by H2O2. In all ird mutants, the increased expression level of the fbp1 gene can be interpreted as a lack of glucose repression in these mutants. To investigate the mechanisms of the oxidative stress response .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.25.3
- DOI:
- 10.4238/2013.October.25.3
Prevalence of diabetes and impaired fasting glucose in Uygur children of Xinjiang, China
Authors: J. Zhang1, Y.T. Ma1, X. Xie1, Y.N. Yang1, F. Liu2, X.M. Li1, Z.Y. Fu1, X. Ma1, B.D. Chen2, Y.Y. Zheng1, Z.X. Yu1 and Y. Chen1
This study was designed to estimate the prevalence of diabetes and impaired fasting glucose (IFG) in Xinjiang children in western China. Data were obtained from the Chun-Miao Project, a community-based, cross-sectional study designed to investigate the prevalence and risk factors of diabetes in children of the Chinese Uygur population in Xinjiang from Feb.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.24.13
- DOI:
- 10.4238/2013.October.24.13
Protein transduction domain-hA20 fusion protein protects endothelial cells against high glucose-induced injury
Authors: C.L. Hou, Q. Huang, Y. Wei, W. Zhang, J.H. Mi, D.J. Ying and Z.H. Zhou
We constructed a plasmid containing a protein transduction domain (PTD) and a human A20 (hA20) gene fragment; the fusion protein was obtained by highly expressing this plasmid in the yeast Pichia pastoris GS115. The plasmid was obtained by adding 9xArg and EcoRÐ? recognition sites to the end of the primer, and 6xHis-Tag and .. Read More»
- Genet. Mol. Res. 11(3):
- 2012.July.19.9
- DOI:
- 10.4238/2012.July.19.9
RXR agonists inhibit high glucose-induced upregulation of inflammation by suppressing activation of the NADPH oxidase-nuclear factor-?ºB pathway in human endothelial cells
Authors: R.B. Ning, J. Zhu, D.J. Chai, C.S. Xu, H. Xie, X.Y. Lin, J.Z. Zeng and J.X. Lin
An inflammatory response induced by high glucose is a cause of endothelial dysfunction in diabetes and is an important contributing link to atherosclerosis. Diabetes is an independent risk factor of atherosclerosis and activation of retinoid X receptor (RXR) has been shown to exert anti-atherogenic effects. In the present study, we examined the effects of.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.13.3
- DOI:
- 10.4238/2013.December.13.3
Screening and prevention of neonatal glucose 6-phosphate dehydrogenase deficiency in Guangzhou, China
Authors: J. Jiang, B. Li, W. Cao, X. Jiang, X. Jia, Q. Chen and J. Wu
We aimed to summarize the results of screening protocol and prevention of neonatal glucose 6-phosphate dehydrogenase (G6PD) deficiency during a 22-year-long period to provide a basis of reference for the screening of this disease. About 1,705,569 newborn subjects in Guangzhou City were screened for this deficiency. Specimens w.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.June.9.13
- DOI:
- http://dx.doi.org/10.4238/2014.June.9.13
Resistin expression in adipose tissues and its effect on glucose metabolism in rats with brain injury
Authors: R. Zhang1, Z.Y. Wang1, L.L. Zhu1, F. Wu1, D.Q. Chen1, L.F. Sun1 and Z.Q. Lu2
Resistin (RSTN) expression in subcutaneous adipose tissue, and its effect on glucose metabolism in rats with traumatic brain injury, was investigated using real-time PCR, western blots, and enzyme linked immunoassays. Our results show that the expression of RSTN mRNA (3.192 ± 0.046, 4.016 ± 0.010, 6.004 ± 0.020, 8.213 ± 0.013, .. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017659
- DOI:
- 10.4238/gmr.15017659