Glucose

Effects of eplerenone on the activation of matrix metalloproteinase-2 stimulated by high glucose and interleukin-1�² in human cardiac fibroblasts

Authors: J.F. Chi, H. Uzui, H.Y. Guo, T. Ueda and J.D. Lee

The aim of this study was to determine the influence of high glucose (HG) and interleukin (IL)-1β on human cardiac fibroblast (HCF) functions, and to evaluate the effects of eplerenone in these responses. HCFs were cultured in normal or HG media in the absence or presence of IL-1β and/or eplerenone. We assessed matri.. Read More»

Genet. Mol. Res. 13(3):

2014.January.24.4

DOI:

10.4238/2014.January.24.4

Mechanism of pingyangmycin-induced apoptosis of cultured human umbilical vein endothelial cells

Authors: Y.D. Huang, X. Tong, Q. Chen, S.W. Xia, Y. Zhuo, Z.H. Kang and X.Y. Xue

In this study, we investigated the effects of pingyangmycin (PYM) on the growth inhibition and apoptosis of human umbilical vein endothelial cells (HUVEC). In this study, we aimed to explore the optimal concentration of PYM to induce the apoptosis of HUVEC and to determine its mechanism of action. After treatment of HUVEC with.. Read More»

Genet. Mol. Res. 16(2):

gmr16029298

DOI:

10.4238/gmr16029298

Relationship between male sterility and �²-1,3-glucanase activity and callose deposition-related gene expression in wheat (Triticum aestivum L.)

Authors: H.Z. Liu, G.S. Zhang, W.W. Zhu, Q.S. Ba, N. Niu, J.W. Wang,S.C. Ma and J.S. Wang

In previous studies, we first isolated one different protein β-1,3-glucanase using two-dimensional electrophoresis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry from normal wheat (Triticum aestivum L.) and chemical hybridization agent-induced male sterility (CIMS) wheat. In this experiment, β-1,3-glucanase acti.. Read More»

Genet. Mol. Res. 14(1):

2015.January.26.12

DOI:

10.4238/2015.January.26.12

Transcriptome analysis of Arabidopsis seedlings responses to high concentrations of glucose

Authors: L. Han, J.L. Li, M. Jin and Y.H. Su

Sugars acting as fuel energy or as signaling molecules play important roles in plant growth and development. Although sugars associated with early seedling development have been analyzed in detail, few studies have examined the effect of sugar on genome-wide gene transcription. To analyze the role of glucose on the genomic level, we examined the response .. Read More»

Genet. Mol. Res. 14(2):

2015.May.11.11

DOI:

10.4238/2015.May.11.11

Genes involved in glucose repression and oxidative stress response in the fission yeast Schizosaccharomyces pombe

Authors: K.G. Suslu, B. Palabiyik and G. Temizkan

We looked for changes in gene expression and novel genes that could be involved in the interaction between glucose repression and oxidative stress response in the fission yeast, Schizosaccharomyces pombe, using a constitutive invertase mutant, ird11, which is resistant to glucose. BLAST analysis was made of the S. pombe genome.. Read More»

Genet. Mol. Res. 10(4):

2011.November.8.4

DOI:

10.4238/2011.November.8.4

Developmental changes in the expression of the GLUT2 and GLUT4 genes in the longissimus dorsi muscle of Yorkshire and Tibetan pigs

Authors: Y. Liang, X.M. Yang, Y.R. Gu, X. Tao, Z.Z. Zhong, J.J. Gong, X.H. Chen and X.B. Lv

Glucose transporter proteins 2 and 4 (GLUT2 and GLUT4) play important roles in glucose transport and energy metabolism. Changes in the levels of GLUT2 and GLUT4 mRNA were measured in longissimus dorsi muscle from the lean Yorkshire and fat Tibetan pig breeds at six different time points (1, 2, 3, 4, 5, and 6 months) with quantitative real-time polymerase .. Read More»

Genet. Mol. Res. 14(1):

2015.February.13.7

DOI:

10.4238/2015.February.13.7

A potential protective role for thiamine in glucose-driven oxidative stress

Authors: B. Palabiyik, F. Jafari Ghods and E. Onay Ucar

The relationship between glucose repression and the oxidative stress response was investigated in Schizosaccharomyces pombe wild type cells (972h-) and glucose repression resistant mutant type cells (ird11). We aimed to reveal the mechanism of simultaneous resistance to glucose repression and oxidati.. Read More»

Genet. Mol. Res. 13(3):

2014.July.25.13

DOI:

10.4238/2014.July.25.13

Gene expression and nutrient utilization in the basideomycete Moniliophthora perniciosa suggest the existence of regulatory mechanisms of catabolite repression

Authors: I.S. Ganda

Genet. Mol. Res. 9(3):

vol9-3ta033

DOI:

10.4238/vol9-3ta033

Effect of GBOT on blood lipid and blood glucose metabolism in rats with atherosclerosis

Authors: A. Rong, G. Borjihan and Y.J. Qiao

We observed the variation in in vivo blood lipid and blood glucose metabolism in rats with atherosclerosis after 5-(3,4-dihydroxy-phenyl)-1-piperidin-1-yl-penta-2,4-dien-1-one (GBOT) administration. Wistar rats aged 10 weeks received a high-fat diet to establish the atherosclerosis model. Metabolic indices related to blood lipid and blood glucose were mea.. Read More»

Genet. Mol. Res. 14(3):

2015.July.14.6

DOI:

10.4238/2015.July.14.6

Effect of rosuvastatin on high glucose-induced endoplasmic reticulum stress in human umbilical vein endothelial cells

Authors: J.Z. Xu, Y.L. Chai and Y.L. Zhang

It is well established that endothelial injury plays an essential role in atherosclerotic plaque formation. Accumulating evidence has shown that high glucose levels may detrimentally affect cultured endothelial cells through endoplasmic reticulum (ER) stress. In this study, we investigated the effect of rosuvastatin on high gl.. Read More»

Genet. Mol. Res. 15(4):

gmr15048935

DOI:

10.4238/gmr15048935