Goat
Discovery of differentially expressed genes in cashmere goat (Capra hircus) hair follicles by RNA sequencing
Authors: X. Qiao, J.H. Wu,, R.B. W, R. Su, C. Li, Y.J. Zhang1, R.J. Wang, Y.H. Zhao, Y.X. Fan, W.G. Zhang and J.Q. Li
The mammalian hair follicle (HF) is a unique, highly regenerative organ with a distinct developmental cycle. Cashmere goatCapra hircus) HFs can be divided into two categories based on structure and development time: primary and secondary follicles. To identify differentially expressed genes (DEGs) in the primary and secondary .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038589
- DOI:
- 10.4238/gmr.15038589
Differential expression of Toll-like receptors in goat dominant and nondominant follicles
Authors: G.X. E, Y.J. Zhao, Y.H. Ma, M.X. Chu, Q.H. Hong, S.J. Lv, L. Zhu, F.K. Li, Y.G. Han, X. Wu5and Y.F. Huang
The mechanism of dominant follicle selection is unclear because of its physiological complexity. However, some studies have reported that the immune system plays an important role in reproductive physiology. The objective of the current study was to investigate the differential expression of Toll-like receptors (TLRs) in the d.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049157
- DOI:
- 10.4238/gmr15049157
Methylation differences and expression profiles of the caprine DIO3 gene
Authors: H. Zhang, P.F. Jin, L.L. Niu, L. Li, L.J. Wang, Y. Chen, G.J. Zhang, H.P. Zhang and T. Zhong
DIO3 gene encoding type 3 iodothyronine deiodinase is an imprinted gene, located in the DLK1-DIO3 (delta-like 1 homolog-type 3 iodothyronine deiodinase) imprinted domain, and is potentially involved in degrading excessive amounts of thyroid hormone to protect embryogenesis. However, the underlying regulatory mechanism of the imprinted DIO3 gene expression.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038678
- DOI:
- 10.4238/gmr.15038678
Molecular cloning and functional analysis of MRLC2 in Tianfu, Boer, and Chengdu Ma goats
Authors: H.G. Xu, G.Y. Xu, L. Wan and J. Ma
To determine the molecular basis of heterosis in goats, fluorescence quantitative polymerase chain reaction (PCR) was performed to investigate myosin-regulatory light chain 2 (MRLC2) gene expression in the longissimus dorsi muscle tissues of the Tianfu goat and its parents, the Boer and Chengdu Ma goats. The goat MRLC2 gene was differentially expressed in.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.March.15.7
- DOI:
- 10.4238/2013.March.15.7
Diversity of TNF-�± region in Chinese domestic goats
Authors: G.X. E,R.S. Na,Y.J. Zhao,Y.H. Ma and Y.F. Huang
Tumor necrosis factor-a is a cytokine with a wide range of effects on both lymphoid and non-lymphoid cells. In this study, we identified polymorphisms in major histocompatibility complex class III gene in the 4th exon and the 3' untranslated region of tumor necrosis factor-a to evaluate the immunogenetic diversity of Chinese south indigenous goat. Three s.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.April.17.9
- DOI:
- 10.4238/2015.April.17.9
Transcript analysis of a goat mesenteric lymph node by deep next-generation sequencing
Authors: G.X. E, Y.J. Zhao, R.S. Na and Y.F. Huang
Deep RNA sequencing (RNA-seq) provides a practical and inexpensive alternative for exploring genomic data in non-model organisms. The functional annotation of non-model mammalian genomes, such as that of goats, is still poor compared to that of humans and mice. In the current study, we performed a whole transcriptome analysis .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028262
- DOI:
- 10.4238/gmr.15028262
Polymorphisms of the myostatin gene (MSTN) and its relationship with growth traits in goat breeds
Authors: Z.J. Zhang, Y.H. Ling, L.J. Wang, Y.F. Hang, X.F. Guo, Y.H. Zhang, J.P. Dingand X.R. Zhang
Mutations in the myostatin (MSTN) gene can inactivate its expression and result in a non-functional protein, which leads to dramatic muscularity and a “double-muscling” phenomenon in many species. Using gene sequencing and polymerase chain reaction-single-strand conformation polymorphism methods, polymorphisms of the MSTN gene were investigate.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.2.12
- DOI:
- 10.4238/2013.April.2.12
Use of microsatellite markers to assign goats to their breeds
Authors: R.S. Aljumaah, M.M. Alobre and R.M. Al-Atiyat
We investigated the potential of 17 microsatellite markers for assigning Saudi goat individuals to their breeds. Three local breeds, Bishi, Jabali, and Tohami were genotyped using these markers, and Somali goats were used as a reference breed. The majority of alleles were shared between the breeds, except for some that were specific to each breed. The Gar.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.16
- DOI:
- 10.4238/2015.August.7.16
Low diversity of the major histocompatibility complex class II DRA gene in domestic goats (Capra hircus) in Southern China
Authors: L.P. Chen, G.X. E, Y.J. Zhao, R.S. Na, Z.Q. Zhao, J.H. Zhang, Y.H. Ma, Y.W. Sun, T. Zhong, H.P. Zhang and Y.F. Huang
DRA encodes the alpha chain of the DR heterodimer, is closely linked to DRB and is considered almost monomorphic in major histocompatibility complex region. In this study, we identified the exon 2 of DRA to evaluate the immunogenetic diversity of Chinese south indigenous goat. Two single nucleotide polymorphisms in anuntranslated region and one synonymous.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.18.35
- DOI:
- 10.4238/2015.June.18.35
Cloning and functional analysis of goat SWEET1
Authors: L.Q. Zhu, Z.K. Bao, W.W. Hu, J. Lin, Q. Yang and Q.H. Yu
SWEETs are a recently discovered class of sugar transporters that mediate glucose uptake in the intestine and mammary glands. Our objectives were to clone goat SWEET1 and conduct a functional analysis of its effect on glucose efflux in goat mammary gland epithelial cells. We cloned and sequenced the goat SWEET1 gene from goat mammary glands, then conducte.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.12
- DOI:
- 10.4238/2015.December.16.12