Goat
Silencing FKBP38 gene by siRNA induces activation of mTOR signaling in goat fetal fibroblasts
Authors: Y.T. Fu, X. Zheng, Q. He, X.Y. Jia, Z.X. Guo, R.Y. Yao, Y.F. Wang and Z.G. Wang
FKBP38 (also known as FKBP8) is a unique member of the FK506-binding protein (FKBP) family, and its role is controversial because it acts as an upstream regulator of the mTOR signaling pathway, which controls cell growth, proliferation, and differentiation. This study aimed to explore the role of FKBP38 in the activation of mTOR signaling in Cashmere goat.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.14.30
- DOI:
- 10.4238/2015.August.14.30
Characterization of microRNAs from goat (Capra hircus) by Solexa deep-sequencing technology
Authors: Y.H. Ling, J.P. Ding, X.D. Zhang, L.J. Wang, Y.H. Zhang, Y.S. Li, Z.J. Zhang and X.R. Zhang
MicroRNAs (miRNAs) are an important class of small noncoding RNAs that are highly conserved in plants and animals. Many miRNAs are known to mediate a myriad of cell processes, including proliferation and differentiation, via the regulation of some transcription and signaling factors, which are closely related to muscle development and disease. In this stu.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.June.13.4
- DOI:
- 10.4238/2013.June.13.4
Hair follicle transcriptome profiles during the transition from anagen to catagen in Cashmere goat (Capra hircus)
Authors: Y.X. Fan, R.B. Wu, X. Qiao, Y.J. Zhang, R.J. Wang, R. Su, J.H. Wu, Y. Dong and J.Q. Li
Previous molecular genetic studies of the goat hair life cycle have focused primarily on a limited number of genes and proteins. To identify additional genes that may play important roles in hair follicle cycle regulation, Illumina sequencing technology was used to catalog differential gene expression profiles in the hair growth cycle (anagen to catagen) .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.15
- DOI:
- 10.4238/2015.December.22.15
Complete mitochondrial genome of the Liuyang black goat and its phylogenetic relationship with other Caprinae
Authors: S. Chen, H.M. Ma, G.S. Chen and L.Y. Wang
In this study, the complete mitochondrial genome sequence of the Liuyang black goat was investigated, and phylogenetic relationships between the Liuyang black goat and other species of Caprinae were analyzed. The total length of the mitochondrial genome was 16,715 bp, which consisted of 33.50% A, 27.27% T, 25.98% C, and 13.25%.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028267
- DOI:
- 10.4238/gmr.15028267
Expression profiles of differentially expressed genes affecting fecundity in goat ovarian tissues
Authors: Y.H. Ling, Q. Quan, H. Xiang, L. Zhu, M.X. Chu, X.R. Zhang and C.Y. Han
Although RNA-Seq is an effective method for identifying and exploring novel functional genes in mammals, it has rarely been applied to study fertility-related genes in the goat. In this study, RNA-Seq was used to screen the estrus ovaries of uniparous and multiparous Anhui white goats (AWGs). In total, 15,890 genes were identified and 2201 of these were f.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.23
- DOI:
- 10.4238/2015.December.28.23
Birth of normal kids after microinjection of pronuclear embryos in a transgenic goat (Capra hircus) production program in Brazil
Authors: V.J.F. Freitas, I.A. Serova, L.E. Andreeva, E.S. Lopes J�ºnior, D.I.A. Teixeira, M.F. Cordeiro, D. Rondina, N.R.O. Paula, I.J. Arruda, J.B. Lima Verde, G. Dvoriantchikov, O. Serov
This pilot project was designed to determine if normal kids could be produced after microinjection in pronuclear embryos and subsequent transfer to recipients in a transgenic goat program in Brazil. Twelve donors of the Saanen breed and 17 recipients of an undefined breed were used. The estrus of both donors and recipients was.. Read More»
- Genet. Mol. Res. 2(2):