Growth Hormone
Bell’s palsy following growth hormone therapy in a patient with Prader-Willi syndrome: The first report
Authors: Setila Dalili, Elham Bidabadi, Babak Behnam
Prader–Willi syndrome (PWS) is a complex genetic disorder with different manifestations in infancy and childhood including obesity, type 2 diabetes mellitus, mild to moderate intellectual impairment and learning disabilities. In this syndrome, growth hormone therapy improves outcomes. For the first time, here we report a.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039877
- DOI:
- 10.4238/gmr16039877
Cloning, sequencing, and polymorphisms of the Wistar-Imamichi rat growth hormone gene using PCR-SSCP
Authors: M.Q. Liu1, J.G. Wang2* and X.L. Li2*
We successfully cloned the Wistar-Imamichi (WI) rat growth hormone gene (GenBank accession: GQ890681), which contained 5 exons and 4 introns. Using the polymerase chain reaction-single-strand conformation polymorphism (PCR-SSCP) technique, a novel missense substitution single nucleotide polymorphism was identified and tested for Hardy-Weinberg equilibrium.. Read More»
- Genet. Mol. Res. 13(4):
- 2013.December.4.7
- DOI:
- 10.4238/2013.December.4.7
Construction and functional study of pGN, a mammary gland-specific expression plasmid
Authors: J. Lin, Q.H. Yu, Q. Zhang and Q. Yang
The aim of this study was to construct a mammary gland-specific expression vector, pGN, and to validate its function in expressing growth hormone (GH) both in vitro and in vivo. First, the GH gene was amplified and inserted downstream of the b-casein 5'-arm. Next, the neo gene was cloned downstream of the b-casein 3'-arm as a .. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.30.1
- DOI:
- http://dx.doi.org/10.4238/2014.May.30.1
Dietary methionine effects on IGF-I and GHR mRNA expression in broilers
Authors: A.P. Del Vesco, E. Gasparino, A.R. Oliveira Neto, S.E.F. Guimar�?£es, S.M.M. Marcato and D.M. Voltolini
This study aimed to evaluate liver and breast muscle insulin-like growth factor I (IGF-I) and growth hormone receptor (GHR) gene expression between broilers fed different methionine levels and sources. Broiler chicks were 22 to 42 days old, distributed in 5 treatments (control diet, DL1 - 0.08% DL-methionine, DL2 - 0.24% DL-methionine, MHA-FA1 - 0.11% met.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.10.2
- DOI:
- 10.4238/2013.December.10.2
Doxycycline-regulated growth hormone gene expression system for swine
Authors: B.C. Jiang D.B. Yu L.J. Wang F.L. Dong H.A. Kaleri X.G. Wang N. Ally J. Li H.L. Liu
Although growth hormone gene transgenic animals are much larger than normal animals, they manifest differences that have adverse effects on survival due to overexpression of growth hormone. We developed a stable pig embryonic fibroblast cell line expressing pig growth hormone (pGH) using the Tet-On system, with which we can conditionally manipulate expressio.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.July.10.5
- DOI:
- 10.4238/2012.July.10.5
Acute heat stress and dietary methionine effects on IGF-I, GHR, and UCP mRNA expression in liver and muscle of quails
Authors: A.P. Del Vesco, E. Gasparino, V. Zancanela, D.O. Grieser, S.E.F. Guimar�?£es, C.S. Nascimento, D.M. Voltolini, J. Constantin and F.S. Gasparin
This study evaluated the expression of insulin-like growth factor I (IGF-I), growth hormone receptor (GHR), and uncoupling protein (UCP) mRNA in muscle and liver of quails that were in thermal comfort or exposed to heat stress and that were fed diets with or without methionine supplementation. Meat quails were fed a diet that .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.February.13.12
- DOI:
- 10.4238/2014.February.13.12
Association of chicken growth hormone polymorphisms with egg production
Authors: Y.J. Su, J.T. Shu, M. Zhang, X.Y. Zhang, Y.J. Shan, G.H. Li, J.M. Yin, W.T. Song, H.F. Li and G.P. Zhao
Growth hormone (GH) has diverse functions in animals, together with other hormones from the somatotropic axis. Here, chicken GH (cGH) was investigated in recessive white chickens and Qingyuan partridge chickens as a candidate gene affecting egg production traits. Chicken egg production traits were studied in association with 4.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.4.3
- DOI:
- 10.4238/2014.July.4.3
Sequence analysis of the growth hormone gene of the South American catfish Rhamdia quelen
Authors: B.S. Vaz, G.M. Cerqueira, J.C. Silva, V.H.B. Manzke, C.G.A. Moreira and H.L.M. Moreira
Rhamdia quelen is an important Neotropical catfish species for fisheries and aquaculture in southern Brazil, where it is called Jandia. Like other native Brazilian species of economic importance, R. quelen genetics needs more attention for animal breeding programs. The growth hormone gene is known to be linked to a number of m.. Read More»
- Genet. Mol. Res. 9(4):
- vol9-4gmr708
- DOI:
- 10.4238/vol9-4gmr708
Genetic markers of body composition and carcass quality in grazing Brangus steers
Authors: M.C. Baeza, P.M. Corva, L.A. Soria, G. Rincon, J.F. Medrano, E. Pavan, E.L. Villarreal, A. Schor, L. Melucci, C. Mezzadra and M.C. Miquel
The somatotropic axis is a major regulatory pathway of energy metabolism during postnatal growth in mammals. Genes involved in this pathway influence many economically important traits. The association of selected SNPs in these genes with carcass traits was examined in grazing Brangus steers. These traits included final live w.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.19.3
- DOI:
- 10.4238/2011.December.19.3
Associations of DNA polymorphisms in growth hormone and its transcriptional regulators with growth and carcass traits in two populations of Brangus bulls
Authors: Thomas MG, Enns RM, Shirley KL, Garcia MD, Garrett AJ, and Silver GA
Sequence polymorphisms in the growth hormone (GH) gene and its transcriptional regulators, Pit-1 and Prop-1, were evaluated for associations with growth and carcass traits in two populations of Brangus bulls Chihuahuan Desert Rangeland Research Center (CDRRC, N = 248 from 14 sires) and a cooperating breeding program (COOP, N =.. Read More»
- Genet. Mol. Res. 6(1):