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Growth

Human Genetics   Research Article

Correlation between magnetic resonance perfusion weighted imaging of radiation brain injury and pathology

Authors: X.J. Liu, C.F. Duan, W.W. Fu, L. Niu, Y. Li, Q.L. Sui and W.J. Xu

We used magnetic resonance perfusion weighted imaging and pathological evaluation to examine different stages of radiation-induced brain injury and to investigate the correlation between the relative cerebral blood volume (rCBV) ratio and vascular endothelial growth factor (VEGF). Thirty adult rats were randomly divided into 2 groups: control and radiatio.. Read More»

Genet. Mol. Res. 14(4):
2015
DOI:
10.4238/2015
Human Genetics   Research Article

Construction of an adenoviral expression vector carrying FLAG and hrGFP-1 genes and its expression in bone marrow mesenchymal stem cells

Authors: G.X. Wang, L. Hu2, Z. Zhang and D.P. Liu

The aim of this study was to construct an adenoviral expression vector for vascular endothelium growth factor 121 (VEGF121)-FLAG and humanized Renilla reniformis green fluorescent protein (hrGFP-1) genes, and to observe their expressions in bone marrow mesenchymal stem cells. Using pTG19T-VEGF121 as a template, polymerase chai.. Read More»

Genet. Mol. Res. 13(1):
2014.February.20.8
DOI:
10.4238/2014.February.20.8
Animal Genetics   Short communication

Sequence analysis of the growth hormone gene of the South American catfish Rhamdia quelen

Authors: B.S. Vaz, G.M. Cerqueira, J.C. Silva, V.H.B. Manzke, C.G.A. Moreira and H.L.M. Moreira

Rhamdia quelen is an important Neotropical catfish species for fisheries and aquaculture in southern Brazil, where it is called Jandia. Like other native Brazilian species of economic importance, R. quelen genetics needs more attention for animal breeding programs. The growth hormone gene is known to be linked to a number of m.. Read More»

Genet. Mol. Res. 9(4):
vol9-4gmr708
DOI:
10.4238/vol9-4gmr708
Animal Genetics   Research Article

Effect of atorvastatin on diabetic rat endothelial cells and retinal lesions

Authors: M.C. Bi, X.J. Song, H. Shi, W.X. Xue, C.L. Xu and E. Song

We investigated the effect of atorvastatin on vascular endothelial growth inhibitor (VEGI) expression in rats with diabetic retinopathy. Wistar rats were divided into a blank group and diabetic model group, which was further randomly divided into treatment and control groups. Rats in the treatment group received 10 mg/kg atorvastatin daily, while rats in .. Read More»

Genet. Mol. Res. 14(2):
2015.May.22.16
DOI:
10.4238/2015.May.22.16
Medical Genetics   Research Article

Ebp1 protein expression in cervical cancer tissue and its significance

Authors: L. Liu, D.Y. Xu, S.S. Yang and X.D. Li

The objectives of this study were to observe the changes in expression of ErbB-3 binding protein (Ebp1) in cervical cancer and to investigate their clinic significance. We detected the expression level of Ebp1 in cancerous and adjacent tissues from 56 patients with cervical cancer. We identified 21 Ebp1 positive samples (37.5%) from among the 56 cervical .. Read More»

Genet. Mol. Res. 14(2):
2015.May.22.20
DOI:
10.4238/2015.May.22.20
Medical Genetics   Research Article

Association between EGF and VEGF functional polymorphisms and sporadic colorectal cancer in the Malaysian population

Authors: T.P. Lau, A.C. Roslani, L.H. Lian, P.C. Lee, I. Hilmi, K.L. Goh and K.H. Chua

Growth factors are polypeptides that are critical for the initiation, progression, and metastasis of cancer. Most tumor cells are capable of synthesizing particular growth factors leading to constitutive pathway activation in these cells through autocrine signaling. Epidermal growth factor (EGF) is a potent mitogenic peptide t.. Read More»

Genet. Mol. Res. 13(3):
2014.July.25.9
DOI:
10.4238/2014.July.25.9
Animal Genetics   Research Article

Genetic parameter estimates and response to selection for weight and testicular traits in Nelore cattle

Authors: F.R. Araujo Neto, R.B. L�´bo, M.D.S. Mota and H.N. Oliveira

We estimated genetic parameters for various phases of body and testicular growth until 550 days of age in Nelore cattle, using Bayesian inference, including correlation values and error estimates. Weight and scrotal records of 54,182 Nelore animals originating from 18 farms participating in the Brazilian Nelore Breeding Progra.. Read More»

Genet. Mol. Res. 10(4):
2011.December.19.1
DOI:
10.4238/2011.December.19.1
Plant Genetics   Research Article

Agronomic performance of arabica coffee genotypes in northwest Rio de Janeiro State

Authors: W.P. Rodrigues, H.D. Vieira, D.H.S.G. Barbosa, G.R. Sousa Filho and F.L. Partelli

Considering the productive potential of arabica coffee in the Rio de Janeiro State and the shortage of breeding programs for this species in the state, this study aimed to evaluate the vegetative and productive characteristics of 25 arabica coffee genotypes to indicate 1 or more varieties for the northwest Rio de Janeiro regio.. Read More»

Genet. Mol. Res. 13(3):
2014.July.25.22
DOI:
10.4238/2014.July.25.22
Microbial Genetics   Research Article

Construction and identification of pIRES2-NGF-VEGF165 bicistronic eukaryotic expression vector

Authors: B.N. Li, W.D. Li, H.G. Feng, J.T. Lin and Z.Q. Yuan

We used a simple and efficient method to construct the bicistronic eukaryotic expression vector pIRES2-NGF-VEGF165. The nerve growth factor (NGF) gene was obtained from the genomic DNA of human peripheral blood mononuclear cells by polymerase chain reaction. The NGF cDNA fragment was inserted into the multiple cloning sites of the pI.. Read More»

Genet. Mol. Res. 13(3):
2014.July.25.23
DOI:
10.4238/2014.July.25.23
Animal Genetics   Research Article

Genetic markers of body composition and carcass quality in grazing Brangus steers

Authors: M.C. Baeza, P.M. Corva, L.A. Soria, G. Rincon, J.F. Medrano, E. Pavan, E.L. Villarreal, A. Schor, L. Melucci, C. Mezzadra and M.C. Miquel

The somatotropic axis is a major regulatory pathway of energy metabolism during postnatal growth in mammals. Genes involved in this pathway influence many economically important traits. The association of selected SNPs in these genes with carcass traits was examined in grazing Brangus steers. These traits included final live w.. Read More»

Genet. Mol. Res. 10(4):
2011.December.19.3
DOI:
10.4238/2011.December.19.3