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Growth

Cytogenomics   Research Article

Genetic evaluation using multi-trait and random regression models in Simmental beef cattle

Authors: R.R. Mota, L.F.A. Marques, P.S. Lopes, L.P. da Silva, F.R.A. Neto, M.D.V. de Resende and R.A. Torres

The Brazilian Association of Simmental and Simbrasil Cattle Farmers provided 29,510 records from 10,659 Simmental beef cattle; these were used to estimate (co)variance components and genetic parameters for weights in the growth trajectory, based on multi-trait (MTM) and random regression models (RRM). The (co)variance components and genetic parameters wer.. Read More»

Genet. Mol. Res. 12(3):
2013.July.24.2
DOI:
10.4238/2013.July.24.2
Human Genetics   Research Article

Blood folic acid, vitamin B12, and homocysteine levels in pregnant women with fetal growth restriction

Authors: H.L. Jiang, L.Q. Cao and H.Y. Chen

Deficiencies in nutrients such as folic acid and vitamin B12 may play a role in fetal growth restriction (FGR). However, whether folic acid, vitamin B12, or homocysteine is associated with FGR in Chinese populations remains unclear. This study investigated the relationship between these nutrient deficiencies and FGR in pregnan.. Read More»

Genet. Mol. Res. 15(4):
gmr15048890
DOI:
10.4238/gmr15048890
Medical Genetics   Research Article

Expression of COX-2 and VEGF-C in cholangiocarcinomas at different clinical and pathological stages

Authors: Z. You, L. Bei, L.P. Cheng and N.S. Cheng

The aim of this study was to investigate the expression and clinical significance of cyclooxygenase 2 (COX-2) and vascular endothelial growth factor C (VEGF-C) in cholangiocarcinomas at different clinical and pathological stages. Eighty cholangiocarcinoma samples of patients treated with surgery between January 2012 and January 2014 were collected. Immuno.. Read More»

Genet. Mol. Res. 14(2):
2015.June.9.9
DOI:
10.4238/2015.June.9.9
Cytogenomics   Research Article

Identification and assessment of differentially expressed genes involved in growth regulation in Apostichopus japonicus

Authors: L. Zhu,C.H. Li, X.R. Su, C.Y. Guo, Z. Wang, C.H. Jin,Y. Li,T.W. Li

Rapid and efficient growth is a major consideration and challenge for global mariculture. The differential growth rate of the sea cucumber, Apostichopus japonicus, has significantly hampered the total production of the industry. In the present study, forward and reverse suppression subtractive hybridization libraries were constructed and sequenced from a .. Read More»

Genet. Mol. Res. 12(3):
2013.August.20.4
DOI:
10.4238/2013.August.20.4
Animal Genetics   Research Article

Additive genetic relationship of longevity with fertility and production traits in Nellore cattle based on bivariate models

Authors: M.H. Van Melis, H.N. Oliveira, J.P. Eler, J.B.S. Ferraz, J. Casellas and L. Varona

Survival or longevity is an economically important trait in beef cattle. The main inconvenience for its inclusion in selection criteria is delayed recording of phenotypic data and the high computational demand for including survival in proportional hazard models. Thus, identification of a longevity-correlated trait that could .. Read More»

Genet. Mol. Res. 9(1):
vol9-1gmr710
DOI:
10.4238/vol9-1gmr710
Animal Genetics   Research Article

Polymorphisms in the LPL gene and their association with growth traits in Jiaxian cattle

Authors: L.S. Gui, Y.M. Huang, J.Y. Hong and L.S. Zan

Previous studies showed that the lipoprotein lipase (LPL) gene was involved in metabolism and transport of lipids, suggesting that the LPL is a potential candidate gene affecting growth traits in animals. The aim of this study was to identify polymorphism in the bovine LPL gene and analyze its possible association with growth .. Read More»

Genet. Mol. Res. 15(2):
gmr.15027590
DOI:
10.4238/gmr.15027590
Medical Genetics   Research Article

Growth factor progranulin blocks tumor necrosis factor-�±-mediated inhibition of osteoblast differentiation

Authors: N. Wang, J. Zhang and J.X. Yang

Tumor necrosis factor-a (TNF-a) stimulates osteoclast differentiation and suppresses osteoblast differentiation, leading to bone loss and decreased bone mass in local inflammation areas in patients with rheumatoid arthritis. The growth factor progranulin (PGRN) is expressed in various types of cells and play crucial roles in t.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038126
DOI:
10.4238/gmr.15038126
Animal Genetics   Research Article

Somatic cell nuclear transfer is associated with altered expression of angiogenic factor systems in bovine placentomes at term

Authors: D.B. Campos, P.C. Papa, J.E.B. Marques Jr., F. Garbelotti, L.A. F�¡tima, L.P. Artoni, E.H. Birgel Jr., F.V. Meirelles, J. Buratini Jr., R. Leiser and C. Pfarrer

Low efficiency of somatic cell cloning by nuclear transfer has been associated with alterations of placental vascular architecture. Placental growth and function depend on the growth of blood vessels; VEGF-A and bFGF are the most important factors controlling neovascularization and vascular permeability in the placenta. We hyp.. Read More»

Genet. Mol. Res. 9(1):
vol9-1gmr729
DOI:
10.4238/vol9-1gmr729
Human Genetics   Research Article

Effect of atmospheric fine particles on epidermal growth factor receptor mRNA expression in mouse skin tissue

Authors: X. Han, W.L. Liang, Y. Zhang, L.D. Sun and W.Y. Liang

We investigated the effect of atmospheric fine particles on epidermal growth factor receptor (Egfr) mRNA expression in mouse skin tissue and explored the effect of atmospheric fine particles on skin aging. Forty female BALB/c mice were randomly divided into four groups (each comprising 10 mice) as follows: a saline control gro.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017188
DOI:
10.4238/gmr.15017188
Human Genetics   Research Article

Molecular cloning, polymorphisms, and association analysis of the promoter region of the STAM2 gene in Wuchuan Black cattle

Authors: Y.-Q. Yang, Y.-T. Hui, R.-Y. Liu, R.-G. Jiao, Y. Gong, Y.-Y. Zhang and H.-Q. Xie

The STAM protein plays an important role in the cytokine-related JAK/STAT pathway. We selected the STAM2 gene as a candidate gene that could be linked to growth performance in analysis of a Chinese cattle breed (Wuchuan Black cattle). We examined genetic variants in the promoter region of the STAM2 gene and their associations with eight growth traits in 1.. Read More»

Genet. Mol. Res. 12(3):
2013.September.13.9
DOI:
10.4238/2013.September.13.9