Growth
Genetic analysis of QTL for eye cross and eye diameter in common carp (Cyprinus carpio L.) using microsatellites and SNPs
Authors: S.B. Jin, X.F. Zhang, J.G. Lu, H.T. Fu, Z.Y. Jia and X.W. Sun
A group of 107 F1 hybrid common carp was used to construct a linkage map using JoinMap 4.0. A total of 4877 microsatellite and single nucleotide polymorphism (SNP) markers isolated from a genomic library (978 microsatellite and 3899 SNP markers) were assigned to construct the genetic map, which comprised 50 linkage groups. The total length of the linkage .. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.17.5
- DOI:
- http://dx.doi.org/10.4238/2015.April.17.5
Repair of large segmental bone defects in rabbits using BMP and FGF composite xenogeneic bone
Authors: X. Li, Z. Lin, Y. Duan, X. Shu, A. Jin, S. Min and W. Yi
The objective of this study was to determine the ability of bone morphogenetic protein (BMP) and fibroblast growth factor (FGF) to repair large segmental radial bone defects in rabbits. We treated calf cancellous bones with 3 mg/L BMP (Group A), 5 μg/L FGF (Group B), or 3 mg/L BMP plus 5 μg/L FGF (Group C). A bone damage model was established using .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.11.15
- DOI:
- 10.4238/2015.June.11.15
Inhibition of human chronic myelogenous leukemia K562 cell growth following combination treatment with resveratrol and imatinib mesylate
Authors: X.J. Wang and Y.H. Li
To investigate the effect of treatment with resveratrol combined with imatinib mesylate on human chronic myelogenous leukemia K562 cell growth inhibition and apoptosis, in vitro cultured human chronic myelogenous leukemia K562 cells were incubated with different concentrations of resveratrol and imatinib mesylate when the cells were in the logarithmic pha.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.11.17
- DOI:
- 10.4238/2015.June.11.17
Polymorphisms in the vascular endothelial growth factor (VEGF) gene associated with asthma
Authors: H.Y. Lu, G.L. Zhao, M.F. Fu
It has been proven that vascular endothelial growth factor (VEGF) is involved in airway restoration and the development of asthma. We sought to examine the relevance of VEGF gene polymorphisms to asthma in the Chinese Han population. We extracted the whole genomic DNA from the peripheral blood of 471 participants, including 22.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027859
- DOI:
- 10.4238/gmr.15027859
Expression of transforming growth factor-�²1 in neonatal rats with hyperoxia-induced bronchopulmonary dysplasia and its relationship with lung development
Authors: B. Yan, W. Zhong, Q.M. He, S.Y. Zhang, J.K. Yu and Y.L. Pan
The aim of this study was to detect the expression of transforming growth factor-ß1 (TGF-ß1) in neonatal rats with hyperoxia-induced bronchopulmonary dysplasia (BPD) and to explore its relationship with lung development. Forty-eight rats (2-3 days old) were randomly divided into a hyperoxia group and a control grou.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028064
- DOI:
- 10.4238/gmr.15028064
Influences of species mixture on biomass of Masson pine (Pinus massoniana Lamb) forests
Authors: L.F. Zhang, Y.Y. Huang, L.P. Liu and S.L. Fu
The effect of tree diversity on productivity in subtropical forests in China is poorly understood. We investigated the biomasses of trees, understory vegetation, coarse roots, and fine roots with varying proportions of Pinus massoniana, mixed with other tree species in stands of the same age, to examine the effects of tree diversity. With an increase of P.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.19.5
- DOI:
- 10.4238/2013.September.19.5
Effect of glycerol on GHR and IGF-1 gene expression in breast muscle and on growth of Japanese meat quails
Authors: S.C.C. Silva, E. Gasparino, D.M. Voltolini, A.V. Pires, F. Tanamati, A.L.S. Garcia and D.P. de Oliveira
We evaluated messenger RNA (mRNA) expression of the growth-hormone (GHR) and insulin-like growth factor (IGF-1) genes in 28-day-old Japanese meat quails fed diets containing 0, 8, or 12% dietary glycerol in substitution of corn. Total RNA was extracted from the breast muscle and the DNA was amplified with specific primers using real-time PCR. Feed convers.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.23.3
- DOI:
- 10.4238/2013.September.23.3
Expression of TNF-�±, VEGF, and MMP-3 mRNAs in synovial tissues and their roles in fibroblast-mediated osteogenesis in ankylosing spondylitis
Authors: K.G. Liu, Q.H. He, J.W. Tan and G.J. Liao
The aim of this study was to explore the mRNA levels of tumor necrosis factor-α (TNF-α), vessel endothelial growth factor (VEGF), and matrix metalloproteinase-3 (MMP-3) in synovial tissues in ankylosing spondylitis (AS), and to analyze the functions of these proteins in the differentiation of AS synovial tissue fibroblasts into osteoblasts (OB.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.18.28
- DOI:
- 10.4238/2015.June.18.28
Polymorphisms of the myostatin gene (MSTN) and its relationship with growth traits in goat breeds
Authors: Z.J. Zhang, Y.H. Ling, L.J. Wang, Y.F. Hang, X.F. Guo, Y.H. Zhang, J.P. Dingand X.R. Zhang
Mutations in the myostatin (MSTN) gene can inactivate its expression and result in a non-functional protein, which leads to dramatic muscularity and a “double-muscling” phenomenon in many species. Using gene sequencing and polymerase chain reaction-single-strand conformation polymorphism methods, polymorphisms of the MSTN gene were investigate.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.2.12
- DOI:
- 10.4238/2013.April.2.12
Correlation of tumor relapse and elevated expression of survivin and vascular endothelial growth factor in superficial bladder transitional cell carcinoma
Authors: Y.W. Sun, Q. Xuan, Q.A. Shu, S.S. Wu, H. Chen, J. Xiao, P. Xiang, Y.P. Zhu, F.L. Wang and S.T. Zhao
Survivin and vascular endothelial growth factor (VEGF) are newly discovered tumor markers closely correlated with bladder cancer. We analyzed the expression of survivin and VEGF in paraffin-embedded tumor tissues from 78 patients with bladder transitional cell carcinoma (BTCC) using an immunohistochemistry method. Normal bladder mucosae from 10 non-BTCC c.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.2.21
- DOI:
- 10.4238/2013.April.2.21