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Growth

Medical Genetics   Research Article

Effect of HIF-1a/VEGF signaling pathway on plasma progesterone and ovarian prostaglandin F2a secretion during luteal development of pseudopregnant rats

Authors: X.Y. Pan, Z.H. Zhang, L.X. Wu and Z.C. Wang

The corpus luteum is a temporary endocrine structure in mammals that plays an important role in the female reproductive cycle and is formed from a ruptured and ovulated follicle with rapid angiogenesis. Vascular endothelial growth factor (VEGF) is thought to be vital in normal and abnormal angiogenesis in the ovary, but the molecular regulation of luteal .. Read More»

Genet. Mol. Res. 14(3):
2015.August.3.3
DOI:
10.4238/2015.August.3.3
Microbial Genetics   Research Article

Characterization of microsatellite markers and their correlations with growth traits in Mandarin fish (Siniperca chuatsi)

Authors: T.L. Yi, L. Fang, X.F. Liang, L.F. Sun, J. Li, X.N. Luo, W.J. Guo, Y.Q. Dou and J. Sun

Mandarin fish (Siniperca chuatsi) is a traditionally cultured freshwater fish with high commercial value in China. To facilitate marker-assisted selection for genetic improvement of this species, 100 microsatellite markers identifi ed in previous studies were characterized in the 25 largest and 25 smallest individuals. Twenty polymorphic loci were used to.. Read More»

Genet. Mol. Res. 14(3):
2015.August.7.1
DOI:
10.4238/2015.August.7.1
Microbial Genetics   Research Article

Characteristic element of matrix attachment region mediates vector attachment and enhances nerve growth factor expression in Chinese hamster ovary cells

Authors: X.Y. Wang, J.H. Zhang, Q.L. Sun, Z.Y. Yao, B.G. Deng, W.Y. Guo,L. Wang, W.H. Dong, F. Wang, C.P. Zhao and T.Y. Wang

Preliminary studies have suggested that a characteristic element of the matrix attachment region (MAR) in human interferon-β mediates the adhesion of vectors to Chinese hamster ovary (CHO) cells. In this study, we investigated if vector adhesion increased nerve growth factor (NGF) expression in CHO cells. The MAR characteristic element sequence of hu.. Read More»

Genet. Mol. Res. 14(3):
2015.August.7.29
DOI:
10.4238/2015.August.7.29
Human Genetics   Research Article

Serum immunoglobulin E level and its impact on the pregnancy outcome associated with fetal growth restriction: a prospective cohort study

Authors: F. Xiong,Y. Tong,P. Li,T. Huo and M. Mao

We evaluated the relationship between total serum immunoglobulin E (IgE) levels and pregnancy outcome in a prospective cohort study focusing on fetal growth restriction (FGR). Sixty women with FGR and twenty with normal singleton pregnancy were enrolled during their third trimester. Infants were followed up for 6 months. Blood samples were obtained from p.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.27.2
DOI:
http://dx.doi.org/10.4238/2015.April.27.2
Animal Genetics   Research Article

Tetradecyl 2,3-dihydroxybenzoate promotes functional recovery after spinal cord injury in adult rats

Authors: Y.M. Ding, J.Y. Zhu, S.J. Zhang, S.S. Zhang, C. Wang, L.L. Wang and X. Zhang

Tetradecyl 2,3-dihydroxybenzoate (ABG001) is a small molecule separated from gentian extract that has a similar effect to nerve growth factor. It is not clear whether it can promote functional recovery in animals suffering from a central nervous system injury. In order to explore the role of ABG001 in restoration of tissue str.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028653
DOI:
10.4238/gmr.15028653
Human Genetics   Research Article

Changes in growth factor levels in the cerebrospinal fluid of autism patients after transplantation of human umbilical cord blood mononuclear cells and umbilical cord-derived mesenchymal stem cells

Authors: Q. Li, C.-F. Chen, D.-Y. Wang, Y.-T. L�¼, Y. Huan, S.-X. Fang,Y. Han, R.-C. Ge and X.-W. Ch

 -.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027526
DOI:
10.4238/gmr.15027526
Human Genetics   Research Article

Expression and prognostic influence of NF-�ºB and EGFR in esophageal cancer

Authors: Y.Q. Zhang, J.J. Zhang , H.J. Song and D.W. Li

The goal of this study was to investigate the expression profiles of nuclear factor-kappa B (NF-κB) and epidermal growth factor receptor (EGFR) in esophageal cancer and to determine their association with tumor prognosis. This study included 40 esophageal cancer patients [22 men and 18 women; average age = 62.7 ± 3.9 years; tumor-node-metasta.. Read More»

Genet. Mol. Res. 14(4):
2015.December.14.9
DOI:
10.4238/2015.December.14.9
Human Genetics   Research Article

Effects of HIF prolyl-hydroxylase-2 gene silencing on HCG-induced vascular endothelial growth factor expression in luteal cells

Authors: Z.H. Zhang, D.Z. Yin, X.S Pang and Z.C. Wang

Vascular endothelial growth factor (VEGF)-dependent angiogenesis plays a crucial role in corpus luteum formation and its functional maintenance in mammalian ovaries. We recently reported that activation of hypoxia-inducible factor (HIF)-1α signaling contributes to the regulation of VEGF expression in luteal cells (LCs) in response to human chorionic.. Read More»

Genet. Mol. Res. 14(4):
2015.December.14.2
DOI:
10.4238/2015.December.14.2
Animal Genetics   Research Article

Effect of dietary Bacillus subtilis on proportion of Bacteroidetes and Firmicutes in swine intestine and lipid metabolism

Authors: C. Cui, C.J. Shen, G. Jia and K.N. Wang

The ratio of Bacteroidetes and Firmicutes bacterial groups in the gut can affect the ability to absorb nutrients. We investigated the effect of probiotic Bacillus subtilis supplementation of diets on growth performance, fat deposition, blood lipids, copy numbers, and percentage of Bacteroidetes and Firmicutes in cecal contents, as well as mRNA expression .. Read More»

Genet. Mol. Res. 12(2):
2013.May.23.1
DOI:
10.4238/2013.May.23.1
Animal Genetics   Research Article

Effects of autologous SCF- and G-CSF-mobilized bone marrow stem cells on hypoxia-inducible factor-1 in rats with ischemia reperfusion renal injury

Authors: L.Y. Bi,D.A. Zhao,D.S. Yang,J.G. Guo,B. Liang,R.X. Zhang,J.L. Zhao,H.T. Bai and S.J. Li

To explore the mechanism whereby stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF) jointly mobilize bone marrow stem cells (BMSCs) and promote kidney repair, male Sprague-Dawley rats were randomly assigned into 4 groups. In the treatment control group, rats were administered SCF (200 μg· kg-1·day-1) and G-CSF (50 &m.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.27.25
DOI:
http://dx.doi.org/10.4238/2015.April.27.25