Growth
Analysis of the expression of HMGB-1, CXCL16, miRNA-30a, and TGF-�²1 in primary nephritic syndrome patients and its significance
Authors: W.J. Wang, X.Q. Qu, X.M. Yu, W. Lv and H.Y. Yu
We investigated the expression levels of high-mobility group box protein 1 (HMGB-1), CXC chemokine ligand 16 (CXCL16), microRNA (miRNA)-30a and transforming growth factor b1 (TGF-b1) in primary nephritic syndrome (PNS) patients and the clinical significance of this expression. A total of 56 patients with PNS were included in the PNS group, while 50 health.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.19.17
- DOI:
- 10.4238/2015.August.19.17
Vascular endothelial growth factor gene is associated with hypertensive cerebellar hemorrhage and rehabilitative treatment
Authors: Q.S. He, L.F. Yang, W.B. Wang, B. Yuan, L.Y. Zhang and X.J. Guo
Early rehabilitative therapy is important for patients with hypertensive cerebral hemorrhage to improve long-term function of the extremities. Vascular endothelial growth factor (VEGF) is closely associated with the pathogenesis of hypertension. To identify the markers contributing to the genetic susceptibility to hypertensive cerebellar hemorrhage (HCH) .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.19.18
- DOI:
- 10.4238/2015.August.19.18
CpG ODN 1826 enhances radiosensitivity of the human lung cancer cell line A549 in a rat model
Authors: W. Yan, T.-Y. Sun, C.-M. Yang, M. Jia, J. Li, H.-L. Tang and Y.-F. Zhou
This study investigated the effects of CpG ODN1826 plus radiotherapy (RT) on tumor growth and angiogenesis of subcutaneous tumor in a rat model. Four treatment groups were tested in which rats were injected with 100 μL CpG ODN1826 (1 μg/μL) or 100 μL vehicle, with and without exposure to 8 Gy after 2 h. At 7 days after inoculation of lung canc.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.19.13
- DOI:
- 10.4238/2015.August.19.13
Influence of sirolimus-induced TGF-�² secretion on mouse Treg cell proliferation
Authors: J.N. Li, J.X. Li, H.L. Huang, X.L. Zhu, H. Ding, C.F. Huang, J. Lin, J.G. Huang, Z.C. Wu, M. Ashraf, Y.G. Wang, X.K. Li, S.Y. Zheng, J.M. Chen, H.M. Guo, J. Zhuang and P. Zhu
We examined the effects of co-culturing CD4+ CD25+ Treg cells with sirolimus or cyclosporin A on Treg cell proliferation and differentiation and on transforming growth factor-β (TGF-β) and Foxp3 expression. CD4+ CD25+ Treg cells were harvested from mononuclear cells of spleens of C57BL/6 mice using immunomagnetic beads and divided into control, .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.4
- DOI:
- 10.4238/2015.December.28.4
Effects of microwave ablation or its combination with whole-body chemotherapy on serum vascular endothelial growth factor levels in patients with stage IIIB/IV NSCLC
Authors: Y.H. Sun, P.Y. Song, Y. Guo, M. Pang, W.-N. He, W.H. Zhang and L.J. Sheng
We aimed to analyze the changes of serum vascular endothelial growth factor (VEGF) before and after microwave ablation (MWA) in patients with stage IIIB-IV non-small cell lung cancer (NSCLC), and to observe the effects of MWA combined with chemotherapy on short-term therapeutic efficacy and long-term survival. Concentrations of serum VEGF in 20 healthy su.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.21.8
- DOI:
- 10.4238/2015.August.21.8
Polymorphisms in GJA1 and their association with growth traits in chicken
Authors: M. Shahjahan, R.R. Liu, G.P. Zhao, J.J. Zhang, M.Q. Zheng, Q.H. Li and J. Wen
This study aimed to screen single nucleotide polymorphisms (SNPs) in the chicken gap junction protein alpha 1 (GJA1) gene, and to investigate their association with five growth traits measured in 269 chickens encompassing Chinese indigenous Beijing-You (BJY) and commercial Cobb broiler (CB) populations. Four variants were detected in the chicken GJA1 gene.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.33
- DOI:
- 10.4238/2015.December.28.33
Association of genetic variations in the ACLY gene with growth traits in Chinese beef cattle
Authors: M.N. Li, X. Guo, P.J. Bao, X.Y. Wu, X.Z. Ding, M. Chu, C.N. Liang and P. Yan
ATP citrate lyase (ACLY) is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA, which is a key precursor of both fatty acid and mevalonate synthesis pathways. Genetic variation of the ACLY gene may influence multiple traits associated with animal production. Here, we identified three non-synonymous mutati.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028250
- DOI:
- 10.4238/gmr.15028250
Microsatellite DNA markers and their correlation with growth traits in mandarin fish (Siniperca chuatsi)
Authors: L.F. Sun, J. Li, X.F. Liang, T.L. Yi, L. Fang, J. Sun, Y.H. He, X.N. Luo, Y.Q. Dou and M. Yang
The mandarin fish (Siniperca chuatsi) is a traditionally cultured freshwater fish with high commercial value in China. To facilitate marker-assisted selection in genetic improvement of this species, 120 microsatellite markers from the literature were characterized in the 25 largest and 25 smallest individuals. Eighteen polymorphic loci were then used to g.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.22
- DOI:
- 10.4238/2015.December.29.22
Shock wave treatment enhances endothelial proliferation via autocrine vascular endothelial growth factor
Authors: Y.Z. Peng, K. Zheng, P. Yang, Y. Wang, R.J. Li, L. Li, J.H. Pan and T. Guo
Extracorporeal cardiac shock wave (SW) therapy is an effective, safe, and non-invasive therapeutic strategy for severe coronary artery disease. Shock wave therapy might affect cardiac tissues because of its ability to promote angiogenesis. In this report, we investigated if the up-regulation of vascular endothelial growth factor (VEGF) by SW therapy is in.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.30
- DOI:
- 10.4238/2015.December.29.30
Effect of polymorphisms of vascular endothelial growth factor on prognosis in osteosarcoma patients
Authors: X.D. Li, D.D. Yu, J.R. Lu, C. Wu and W.X. Jin
We investigated the association between vascular endothelial growth factor (VEGF) gene +1612G/A, -634C/G, and +936G/C and the clinical outcome of osteosarcoma. Genomic DNA was isolated from blood samples, and 3 VEGF gene polymorphisms (+1612G/A, -634C/G, and +936G/C) were analyzed using polymerase chain reaction-restriction fragment length polymorphism. O.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.30.8
- DOI:
- http://dx.doi.org/10.4238/2015.April.30.8