Growth
Clinical characteristics of patients with non-small cell lung cancers harboring anaplastic lymphoma kinase rearrangements and primary lung adenocarcinoma harboring epidermal growth factor receptor mutations
Authors: L. Xu, J. Lei, Q.Z. Wang, J. Li and L. Wu
Echinoderm microtubule associated protein like 4-anaplastic lymphoma kinase (EML4-ALK) gene rearrangements and epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) have been intensively studied. The objective of this study was to determine the clinicopathological characteristics in genotype-specific subsets of patients w.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.21.18
- DOI:
- 10.4238/2015.October.21.18
Association of CRTC2 gene polymorphisms with growth and meat quality traits of Qinchuan cattle
Authors: H.C. Xu, L.S. Gui, N. Song, Y.Y. Zhang, H.C.Wang and L.S. Zan
Growth and meat quality traits play important roles in the evaluation of cattle productivity and are influenced by genetic and environmental factors. CRTC2 is a recently discovered gene related to obesity that may influence fat deposition. The aim of the current study was to detect polymorphisms of bovine CRTC2 and explore their relationships to growth an.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.21.12
- DOI:
- 10.4238/2015.October.21.12
Isolation of Pantoea ananatis from sugarcane and characterization of its potential for plant growth promotion
Authors: J.F. da Silva, R.R. Barbosa, A.N. de Souza, O.V. da Motta, G.N. Teixeira, V.S. Carvalho, A.L.S.R de Souza and G.A. de Souza Filho
Each year, approximately 170 million metric tons of chemical fertilizer are consumed by global agriculture. Furthermore, some chemical fertilizers contain toxic by-products and their long-term use may contaminate groundwater, lakes, and rivers. The use of plant growth-promoting bacteria may be a cost-effective strategy for par.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.30.6
- DOI:
- 10.4238/2015.November.30.6
Relationship of EGFR DNA methylation with the severity of non-small cell lung cancer
Authors: J. Li, X.F. Jia, J. Liu, J.J. Liu and H.B. Zhao
The aim of this study was to study the relationship of EGFR DNA methylation with the severity of non-small-cell lung cancer (NSCLC). We enrolled 54 patients with NSCLC between March 2013 and June 2014 from Department of Cardiothoracic Surgery in our hospital. The methylation levels in the promoter region of the EGFR gene in ca.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.5.5
- DOI:
- 10.4238/2015.October.5.5
A rapid method to increase the number of F1 plants in pea (Pisum sativum) breeding programs
Authors: M.A. Esp�³sito P. Almir�³n I. Gatti V.P. Cravero F.S.L. Anido E.L. Cointry
In breeding programs, a large number of F2 individuals are required to perform the selection process properly, but often few such plants are available. In order to obtain more F2 seeds, it is necessary to multiply the F1 plants. We developed a rapid, efficient and reproducible protocol for in vitro shoot regeneration and rooting of seeds using 6-benzylaminop.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.June.18.1
- DOI:
- 10.4238/2012.June.18.1
Neural-endocrine mechanisms of respiratory syncytial virus-associated asthma in a rat model
Authors: Q.G. Li X.R. Wu X.Z. Li J. Yu Y. Xia A.P. Wang J. Wang
We examined the underlying neural-endocrine mechanisms of asthma associated with respiratory syncytial virus infection. Thirty Sprague-Dawley rats were randomly divided into control group, respiratory syncytial virus (RSV) group, and anti-nerve growth factor (NGF) IgG group. An RSV infection model was established by nasal drip once a week. In the anti-NGF.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.August.24.3
- DOI:
- 10.4238/2012.August.24.3
Doxycycline-regulated growth hormone gene expression system for swine
Authors: B.C. Jiang D.B. Yu L.J. Wang F.L. Dong H.A. Kaleri X.G. Wang N. Ally J. Li H.L. Liu
Although growth hormone gene transgenic animals are much larger than normal animals, they manifest differences that have adverse effects on survival due to overexpression of growth hormone. We developed a stable pig embryonic fibroblast cell line expressing pig growth hormone (pGH) using the Tet-On system, with which we can conditionally manipulate expressio.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.July.10.5
- DOI:
- 10.4238/2012.July.10.5
Microdeletions in 16p11.2 and 13q31.3 associated with developmental delay and generalized overgrowth
Authors: A.M. George J. Taylor D.R. Love
Chromosome microarray analysis of patients with developmental delay has provided evidence of small deletions or duplications associated with this clinical phenotype. In this context, a 7.1- to 8.7-Mb interstitial deletion of chromosome 16 is well documented, but within this interval a rare 200-kb deletion has recently been defined that appears to be assoc.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.3.1
- DOI:
- 10.4238/2012.September.3.1
Expression and function of PDGF-�± in columnar epithelial cells of age-related cataracts patients
Authors: J. Wei, H. Tang, Z.Q. Xu, B. Li, L.Q. Xie and G.X. Xu
We studied the expression and function of platelet-derived growth factor A (PDGF-α) in the lens epithelial cells of cataracts patients. Ninety age-related cataracts patients were recruited in our hospital between January 2012 and January 2014. The expression levels of platelet-derived growth factor receptor (PDGFR) in the anterior capsule of the len.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.26.28
- DOI:
- 10.4238/2015.October.26.28
Blockade of S100A3 activity inhibits murine hair growth
Authors: W. Guan, Q. Deng, X.L. Yu, Y.S. Yuan, J. Gao, J.J. Li, L. Zhou, P. Xia, G.Y.Q. Han, W. Han and Y. Yu
Using mouse gene expression microarray analysis, we obtained dynamic expression profiles of the whole genome in a depilation-induced hair growth mouse model. S100A3 expression increased during the anagen phase and returned to normal during the telogen phase. The effects of S100A3 blockade on the hair growth cycle were examined in mice after subcutaneous i.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.14
- DOI:
- 10.4238/2015.October.28.14