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Growth

Medical Genetics   Research Article

Correlation between expression and significance of �´-catenin, CD31, and VEGF of non-small cell lung cancer

Authors: X.L. Liu, L.D. Liu, S.G. Zhang, S.D. Dai, W.Y. Li and L. Zhang

We analyzed the expression and clinical significance of δ-catenin in non-small cell lung cancer (NSCLC) and investigated prognosis using human lung cancer samples. Eighty-nine NSCLC patients underwent operation between January and March 2009. There were 53 cases of squamous cell carcinoma, 31 adenocarcinoma, and 5 large cell carcinoma. δ-Caten.. Read More»

Genet. Mol. Res. 14(4):
2015.October.28.10
DOI:
10.4238/2015.October.28.10
Microbial Genetics   Research Article

Alpaca fiber growth is mediated by microRNA let-7b via down-regulation of target gene FGF5

Authors: T. Wang, Y. Zhang, H.D. Wang, Y. Shen, N. Liu, J. Cao, X.J. Yu, C.S. Dong and X.Y. He

MicroRNAs are very small endogenous RNA molecules that play a crucial role in an array of biological processes, including regulation of skin morphogenesis. The microRNA let-7b is thought to modulate animal hair growth, by binding target genes that encode growth factors. Fibroblast growth factor 5 (FGF5) has been previously reported to be involved in the i.. Read More»

Genet. Mol. Res. 14(4):
2015.October.28.38
DOI:
10.4238/2015.October.28.38
Medical Genetics   Research Article

Screening of polymorphisms located in the FGF20 and TMEM175 genes in North Chinese Parkinson�s disease patients

Authors: C.C. Jing, X.G. Luo, H.G. Cui, F.R. Li, P. Li, E.Z. Jiang, Y. Ren and H. Pang

Genome-wide association studies have reported numerous susceptibility loci for Parkinson’s disease (PD). However, there have been few replication studies examining these loci in northern Chinese populations. To evaluate the relationships among 3 polymorphic markers located in the fibroblast growth factor 20 and transmembrane protein 175 genes and th.. Read More»

Genet. Mol. Res. 14(4):
2015.October.28.30
DOI:
10.4238/2015.October.28.30
Bioinformatics   Research Article

Analysis of genetic diversity in Larix gmelinii (Pinaceae) with RAPD and ISSR markers

Authors: L. Zhang H.G. Zhang X.F. Li

Dahurian larch (Larix gmelinii), a deciduous conifer, is the northernmost tree, native to eastern Siberia and nearby regions of China. We used growth traits and molecular markers to assess genetic variation in different L. gmelinii growing regions; 105 individual samples were collected from seven regions of the Qingshan Forestry Centre, Heilongjiang Province.. Read More»

Genet. Mol. Res. 12(1):
2013.January.24.12
DOI:
10.4238/2013.January.24.12
Animal Genetics   Research Article

Polymorphisms in FGFBP1 and FGFBP2 genes associated with carcass and meat quality traits in chickens

Authors: A.M. Fel�­cio C. Boschiero J.C.C. Balieiro M.C. Ledur J.B.S. Ferraz A.S.A.M.T. Moura L.L. Coutinho

In the past, the focus of broiler breeding programs on yield and carcass traits improvement led to problems related to meat quality. Awareness of public concern for quality resulted in inclusion of meat quality traits in the evaluation process. Nevertheless, few genes associated with meat quality attributes are known. Previous studies mapped quantitative .. Read More»

Genet. Mol. Res. 12(1):
2013.January.24.13
DOI:
10.4238/2013.January.24.13
Microbial Genetics   Research Article

VEGF, eNOS, and ABCB1 genetic polymorphisms may increase the risk of osteonecrosis of the femoral head

Authors: Z.C. Zhou, S.Z. Gu, J. Wu and Q.W. Liang

We investigated the associations between vascular endothelial growth factors (VEGF), endothelial nitric oxide synthase (eNOS), and ATP-binding cassette subfamily B member 1 transporter (ABCB1) polymorphisms and the risk of osteonecrosis of the femoral head (ONFH). Published studies were reviewed and analyzed based on predefined selection criteria. The str.. Read More»

Genet. Mol. Res. 14(4):
2015.October.28.31
DOI:
10.4238/2015.October.28.31
Animal Genetics   Research Article

Polymorphisms of the bovine growth differentiation factor 9 gene associated with superovulation performance in Chinese Holstein cows

Authors: K.Q. Tang W.C. Yang S.J. Li L.-G. Yang

Growth differentiation factor 9 (GDF9) belongs to the transforming growth factor Ã?² superfamily and plays a critical role in ovarian follicular development and ovulation rate. We examined the bovine GDF9 gene polymorphism and analyzed its association with superovulation performance. Based on the sequence of the bovine GDF9 gene, six pairs of primers were d.. Read More»

Genet. Mol. Res. 12(1):
2013.February.8.3
DOI:
10.4238/2013.February.8.3
Medical Genetics   Research Article

Vascular endothelial growth factor -634 G/C polymorphism and risk of cancer: an updated meta-analysis

Authors: J.Y. Ban, J.I. Shin and C.-H. Oh

The association between vascular endothelial growth factor (VEGF) gene polymorphisms and risk of cancer has been investigated in several studies published previously; however, the individual results are inconclusive. Therefore, we performed a meta-analysis to establish evidence for an association between the VEGF -634 G/C polymorphism and risk of cancer. .. Read More»

Genet. Mol. Res. 14(4):
2015.October.29.11
DOI:
10.4238/2015.October.29.11
Human Genetics   Research Article

An experimental study on the use of icariin for improving thickness of thin endometrium

Authors: A.W. Le, Z.H. Wang, X.Y. Dai, T.H. Xiao, R. Zhuo, B.Z. Zhang, Z.L. Xiao and X.J. Fang

This study aimed to investigate the effect of icariin (ICA) on thin endometrium in a rat model. To this end, 6- to 8-week-old female Sprague Dawley rats (105) were randomly divided into 7 groups: untreated, vehicle-treated (lavage with NaCl), high-dose ICA (lavage with ICA at 200 mgâÂ?Â?kg-1âÂ?Â?day-1), medium-dose ICA (lava.. Read More»

Genet. Mol. Res. 16(1):
gmr16019126
DOI:
10.4238/gmr16019126
Plant Genetics   Research Article

Selection of maize hybrids for tolerance to aluminum in minimal solution

Authors: C.J. Coelho, D. Molin, H.A. Wood Joris, E.F. Caires,J.R. Gardingo and R.R. Matiello

The aim of this study was to determine the Al concentration and the period of exposure of the roots of maize hybrids in minimal solution for efficient selection of genotypes that are Al-tolerant. Two experiments were performed (48 and 96 h of exposure) with increasing doses of Al in minimal solution; the block design was completely randomized in a split-p.. Read More»

Genet. Mol. Res. 14(1):
2015.January.15.16
DOI:
10.4238/2015.January.15.16