Growth
Expression of transforming growth factor-�²1 and connective tissue growth factor in congenital biliary atresia and neonatal hepatitis liver tissue
Authors: F.B. Li1, H. Zhao1, K.R. Peng1, Z.G. Gao2, S.J. Huang2, J.F. Tou2, X.L. Shu3and W.Z. Gu4
We investigated the expression of transforming growth factor-β1 (TGF-β1) and connective tissue growth factor (CTGF) in the liver tissue of infants with congenital biliary atresia and neonatal hepatitis, as well as the relationship between the expression of the two factors and liver fibrosis. Thirty-six infants who met the cholestasis criteria we.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017217
- DOI:
- 10.4238/gmr.15017217
Influence of suppression of CapG gene expression by siRNA on the growth and metastasis of human prostate cancer cells
Authors: B.K. Li, K. Guo, C.Y. Li, H.L. Li, P.P. Zhao,K. Chen,C.X. Liu
This study investigated CapG gene expression in prostate cancer cell lines; in addition, we explored the effects of CapG suppression on DU145 cell growth, and the underlying mechanism with which CapG affects DU145 cell growth and invasiveness. The expression of CapG and 18 related genes in DU145 cells was analyzed by flow cyto.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.28
- DOI:
- 10.4238/2015.December.1.28
A rapid and high-quality method for total RNA isolation from Haematococcus pluvialis
Authors: Q.L. Luo, K.P. Wang, K. Xiao, C.G. Wang and Z.L. Hu
Haematococcus pluvialis, as the most potential natural source of astaxanthin, which is a powerful antioxidant with high economic value, has attracted more and more scientific attention in recent years. An in-depth understanding of the mechanism for how H. pluvialis produces astaxanthin requires the intensive investigations on .. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029614
- DOI:
- 10.4238/gmr16029614
Relationship between vitamin D receptor (VDR) polymorphisms and the efficacy of recombinant human growth hormone (rhGH) treatment in children with idiopathic short stature
Authors: W. Wang, X.P. Luo, L.X. Cai, Z.R. Cui, X.Y. Luo and R.K. Luo
Polymorphisms in the vitamin D receptor (VDR) gene are associated with idiopathic short stature (ISS) in several countries. This study aimed to identify a possible correlation between polymorphisms in the VDR promoter in Chinese children with ISS and the efficacy of the recombinant human growth hormone (rhGH) treatment. Pre-pubertal children with ISS and .. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.8.12
- DOI:
- http://dx.doi.org/10.4238/2015.September.8.12
Identification of nutrient-dependent changes in extracellular pH and acid phosphatase secretion in Aspergillus nidulans
Authors: J.S. Freitas, E.M. Silva, A. Rossi
The present study was designed to identify nutrient-dependent changes in extracellular pH and acid phosphatase secretion in the biA1 palC4 mutant strain of Aspergillus nidulans. The palC4 mutant was selected as lacking alkaline phosphatase, but having substantially increased acid phosphatase activity when grown on solid minima.. Read More»
- Genet. Mol. Res. 6(3):
Polymorphisms of AluI and Hin1I loci of the IGF-1R gene and their genetic effects on growth traits in Bian chickens
Authors: P.F. Wu, D. Wang, C.F. Jin, X.Q. Zhang, H.Q. Wu, L. Zhang, F.X. Ding, K. Z. Xie and G.X. Zhang
Growth traits are important economic traits in broiler chicken production. AluI and Hin1I loci are two restriction sites, which are respectively located in exons 2 and 3 of the IGF-1R gene. These two loci are significantly related to the growth traits in Jinghai Yellow chickens. In this study, a correlation analysis was perfor.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029619
- DOI:
- 10.4238/gmr16029619
Acute heat stress and dietary methionine effects on IGF-I, GHR, and UCP mRNA expression in liver and muscle of quails
Authors: A.P. Del Vesco, E. Gasparino, V. Zancanela, D.O. Grieser, S.E.F. Guimar�£es, C.S. Nascimento, D.M. Voltolini, J. Constantin and F.S. Gasparin
This study evaluated the expression of insulin-like growth factor I (IGF-I), growth hormone receptor (GHR), and uncoupling protein (UCP) mRNA in muscle and liver of quails that were in thermal comfort or exposed to heat stress and that were fed diets with or without methionine supplementation. Meat quails were fed a diet that .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.February.13.12
- DOI:
- 10.4238/2014.February.13.12
Treatment of silicosis with hepatocyte growth factor-modified autologous bone marrow stromal cells: a non-randomized study with follow-up
Authors: W.W. Liu, H.X. Wang, W. Yu, X.Y. Bi, J.Y. Chen, L.Z. Chen, L. Ding, D.M. Han, Z.K. Guo and Y.X. Lei
Pulmonary silicosis is an irreversible and untreatable disease that is characterized by interstitial lesions and perpetual fibrosis in the lungs. This study was performed to determine whether mesenchymal stem cells (MSCs) and hepatocyte growth factor (HGF) could exhibit therapeutic effects on human silicosis. This non-randomized uncontrolled trial compris.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.9.7
- DOI:
- http://dx.doi.org/10.4238/2015.September.9.7
RNA-seq reveals the downregulated proteins related to photosynthesis in growth-inhibited rice seedlings induced by low-energy N+ beam implantation
Authors: Q.F. Chen, H.Y. Ya, W.D. Wang and Z. Jiao
Transcriptomic research based on RNA sequencing (RNA-seq) technology is innovative and will provide new opportunities and biological perspectives for the use of ion-beam implantation in plants. Using RNA-seq, transcriptomes of whole rice seedlings generated from seeds implanted with a low-energy N+ beam were analyzed 96 h afte.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.March.26.9
- DOI:
- 10.4238/2014.March.26.9
Association of a transforming growth factor-�²1 polymorphism with acute coronary syndrome in a Chinese Han population
Authors: Y.N. Yang, B. Zhao, X.M. Li, X. Xie, F. Liu and B.D. Chen
Acute coronary syndrome (ACS) is a complex multifactorial and polygenic disorder that is thought to result from the interaction between an individual’s genetic makeup and various environmental factors. The aim of this study was to investigate the association of a transforming growth factor-β1 (TGF-β1) polymorph.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.April.3.2
- DOI:
- 10.4238/2014.April.3.2