Growth
Long interspersed nucleotide acid element-1 ORF-1 protein promotes proliferation and invasion of human colorectal cancer LoVo cells through enhancing ETS-1 activity
Authors: M.Y. Li, M. Zhu, F. Feng, F.Y. Cai, K.C. Fan, H. Jiang, Z.Q. Wang and E.Q. Linghu
The human proto-oncogene long interspersed nucleotide acid element-1 (LINE-1) open reading frame-1 protein (ORF-1p) is involved in the progress of several cancers. The transcription factor ETS-1 can mediate the transcription of some downstream genes that play specific roles in the regulation of cancerous cell invasion and meta.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.April.14.13
- DOI:
- 10.4238/2014.April.14.13
Use of bone mesenchymal stem cells to treat rats with acute liver failure
Authors: S.F. Yuan, T. Jiang, L.H. Sun, R.J. Zheng, G.Q. Cao, N.Z. Ahat and Y.X. Zhang
This study aimed to isolate mesenchymal stem cells from bone mesenchymal stem cells (BMSCs), determine their therapeutic potential for treating rats with acute liver failure (ALF), further explore the factors that induce liver failure mechanisms, and elucidate the role of bone marrow stem cell therapy and BMSCs on liver homing.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.April.30.10
- DOI:
- 10.4238/2014.April.30.10
Association of chicken growth hormone polymorphisms with egg production
Authors: Y.J. Su, J.T. Shu, M. Zhang, X.Y. Zhang, Y.J. Shan, G.H. Li, J.M. Yin, W.T. Song, H.F. Li and G.P. Zhao
Growth hormone (GH) has diverse functions in animals, together with other hormones from the somatotropic axis. Here, chicken GH (cGH) was investigated in recessive white chickens and Qingyuan partridge chickens as a candidate gene affecting egg production traits. Chicken egg production traits were studied in association with 4.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.4.3
- DOI:
- 10.4238/2014.July.4.3
A glimpse of the endophytic bacterial diversity in roots of blackberry plants (Rubus fruticosus)
Authors: M. Contreras1, P.D. Loeza2, J. Villegas1, R. Farias1 and G. Santoyo1
The aim of this study was to explore the diversity of culturable bacterial communities residing in blackberry plants (Rubus fruticosus). Bacterial endophytes were isolated from plant roots, and their 16S rDNA sequences were amplified and sequenced. Our results show that the roots of R. fruticosus exhibit low colony forming units of bacterial endophytes pe.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038542
- DOI:
- 10.4238/gmr.15038542
Hepatocyte growth factor upregulates nexilin gene expression in cardiomyocytes via JNK pathway
Authors: C. Wang, X. You, C. Jiang, C. Jin, X. Meng and D. Ding
Hepatocyte growth factor (HGF) is a protective factor in myocardial injury, but its mechanisms of action have not yet been fully elucidated. Nexilin, which locates specifically to the Z-disc, is a novel Z-disc protein that enables the Z-discs to persistently withstand the extreme mechanical forces generated during muscle contraction. Therefore, we investi.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.4.12
- DOI:
- 10.4238/2014.July.4.12
Identification of SNPs in growth-related genes in Colombian creole cattle
Authors: R. Martinez, J.F. Rocha, D. Bejarano, Y. Gomez, Y. Abuabara and J. Gallego
Colombian creole cattle have important adaptation traits related to heat tolerance and reproductive and productive efficiency. Romosinuano (ROMO) and Blanco Orejinegro (BON) are the most common breeds used by Colombian cattle breeders. Growth traits are of prime importance in these animals, which are mainly raised for beef production. Genes encoding growt.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038762
- DOI:
- 10.4238/gmr.15038762
Two novel SNPs of the 3-hydroxy-3-methylglutaryl coenzyme A reductase gene associated with growth and meat quality traits in the chicken
Authors: Y. Wei S.K. Zhu S. Zhang R.L. Han Y.D. Tian G.R. Sun X.T. Kang
The enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) is rate-limiting for metabolism of cholesterol; it plays an important role in endogenous cholesterol biosynthesis. We used DNA sequencing technology and created restriction site PCR-RFLP to detect HMGCR SNPs in an F2 resource population of Gushi chicken and Anka broilers. We found a G/T mu.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.November.12.10
- DOI:
- 10.4238/2012.November.12.10
Effect of bradykinin on renal mesangial cell proliferation and extracellular matrix secretion
Authors: C.Y. Liu, L.L. Zhou, Q. Cheng, S.N. Jiang, J. Sheng, J.D. Sun and J.Y. Zhao
Recent studies have found that bradykinin (BK) plays a role in delaying glomerulosclerosis, although the mechanism of this phenomenon remains unclear. Mesangial cell proliferation (MCP) and extracellular matrix (ECM) secretion are important mechanisms for glomerulosclerosis. This study investigated the impact of BK on the plat.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.January.21.18
- DOI:
- http://dx.doi.org/10.4238/2014.January.21.18
Single nucleotide polymorphisms associated with growth traits in Jinghai yellow chickens
Authors: M.A. Abdalhag,T. Zhang, Q.C. Fan, X.Q. Zhang, G.X. Zhang, J.Y. Wang, Y. Wei,Y.J. Wang
Body weight is one of the most important economic traits in the poultry industry. In the present study, a custom SNP Beadchip was used to analyze the association between those 15 SNPs and 12 growth traits of Jinghai yellow chickens, and other important genetic parameters were also calculated and analyzed. The results indicated.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.8.6
- DOI:
- 10.4238/2015.December.8.6
Effects of VEGF/VEGFR/K-ras signaling pathways on miRNA21 levels in hepatocellular carcinoma tissues in rats
Authors: J.Z. Gao, Y.L. Wang, J. Li and L.X. Wei
The aim of this study was to investigate the effects of the vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR)/K-ras signaling pathways on miRNA21 levels in hepatocellular carcinoma tissues in rats. Eighteen male Sprague-Dawley rats were randomly divided into normal control, model, and VEGF blocking agent groups (N = 6/group). The expression of .. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.30.10
- DOI:
- 10.4238/2015.January.30.10