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Growth

Medical Genetics   Research Article

Genetic variations in the IGF-IGFR-IGFBP axis confer susceptibility to lung and esophageal cancer

Authors: X.P. Huang, W.H. Zhou and Y.F. Zhang

Recent evidence suggests that genetic variations in the insulin-like growth factor (IGF)-IGF receptor (IGFR)-IGF binding proteins (IGFBP) axis may impact an individual’s susceptibility to lung and esophageal cancer, but individually published results are inconclusive. Our meta-analysis aimed at providing a more precise e.. Read More»

Genet. Mol. Res. 13(1):
2014.January.24.17
DOI:
10.4238/2014.January.24.17
Human Genetics   Research Article

Role of fibroblast growth factor-23 in the pathogenesis of atherosclerosis in peritoneal dialysis patients

Authors: Y. Zeng, S. Feng, O.Y. Han, H.Y. Shen, D.H. Jin and Y.B. Shi

Several previous studies have demonstrated that elevated levels of fibroblast growth factor-23 (FGF-23) may be involved in atherosclerosis and contribute to the high mortality rate of peritoneal dialysis (PD) patients. The aim of this study was to determine the precise role of FGF-23 in the pathogenesis of atherosclerosis in PD patients. Between April 200.. Read More»

Genet. Mol. Res. 14(1):
2015.January.30.15
DOI:
10.4238/2015.January.30.15
Animal Genetics   Research Article

Characterization and expression of DDX6 during gametogenesis in the Chinese mitten crab Eriocheir sinensis

Authors: Q. Li, Y.L. Wang, J. Xie, W.J. Sun, M. Zhu, L. He and Q. Wang

DDX6 belongs to a family of DEAD-box RNA helicases, which are RNA splicing proteins that ensure the correct folding and structure of mature RNA. Gametogenesis requires the participation of many kinds of RNA. To explore its functions during Eriocheir sinensis gametogenesis, we cloned a full-length DDX6 cDNA sequence from E. sinensis (Es-DDX6) which contain.. Read More»

Genet. Mol. Res. 14(2):
2015.April.30.15
DOI:
10.4238/2015.April.30.15
Microbial Genetics   Research Article

Eucalyptus growth promotion by endophytic Bacillus spp

Authors: I.C.P. Paz R.C.M. Santin A.M. Guimar�£es O.P.P. Rosa A.C.F. Dias M.C. Quecine J.L. Azevedo A.T.S. Matsumura

Clonal eucalyptus plantings have increased in recent years; however, some clones with high production characteristics have vegetative propagation problems because of weak root and aerial development. Endophytic microorganisms live inside healthy plants without causing any damage to their hosts and can be beneficial, acting as plant growth promoters. We is.. Read More»

Genet. Mol. Res. 11(4):
2012.August.17.9
DOI:
10.4238/2012.August.17.9
Medical Genetics   Research Article

Effects of VEGF suppression by small hairpin RNA interference combined with radiotherapy on the growth of cervical cancer

Authors: L. Qi, L.N. Xing, X. Wei and S.G. Song

This study aimed to investigate the inhibition of vascular endothelial growth factor (VEGF) by small hairpin RNA (shRNA) interference combined with radiotherapy on the growth of cervical cancer SiHa cell xenografts in nude mice. The effective pVEGF-shRNA plasmid was screened by reverse transcription-polymerase chain reaction (.. Read More»

Genet. Mol. Res. 13(3):
2014.July.7.2
DOI:
10.4238/2014.July.7.2
Animal Genetics   Research Article

Genetic parameters for growth traits of a Brazilian Bos taurus x Bos indicus beef composite

Authors: Mourao GB, Ferraz JBS, Eler JP, Balieiro JCC, Bueno RS, Mattos EC and Figueiredo LGG

The genetic analysis of composite data is very complicated, mainly because it is necessary to adjust data to the effects of heterosis and breed complementarity, and because there is usually considerable confounding of these data with several other effects, such as contemporary group effects, breed composition of the animal and.. Read More»

Genet. Mol. Res. 6(4):
Animal Genetics   Research Article

Estimation of genetic parameters and variance components for growth traits in Romosinuano cattle in the Colombian humid tropics

Authors: Sarmiento RM and Garcia JP

(Co)variance components and genetic parameters were estimated for body weights of a Romosinuano herd located in Sinú Valley, Cordoba, Colombia. Restricted maximum likelihood methods were used with a univariate animal model for birth weight, weaning weight (270 days), 16-month weight (480 days), weaning daily gain, and p.. Read More»

Genet. Mol. Res. 6(3):
Human Genetics   Research Article

Association between SNPs in vascular endothelial growth factor polymorphisms and risk of renal cell carcinoma: a case-control study

Authors: B.-L. Shen, Q.-S. Qu, S.-Z. Miao and Y.-X. Zhang

We conducted this case-control study to assess the role of the VEGF -2578C/A, +1612G/A, +936C/T and -634G/C gene polymorphisms in the development of renal cell carcinoma (RCC). A hospital-based case-control study was conducted in a 360 consecutive primary RCC patients and 360 age and gender-matched controls during January 2010 and January 2014. The polyme.. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.22.5
DOI:
http://dx.doi.org/10.4238/2015.September.22.5
Bioinformatics   Research Article

Bioinformatic analysis of the effect of type II diabetes on skin wound healing

Authors: K. Ge, J.J. Wu, L. Qian, M.J. Wu, F.L. Wang, B. Xu and T. Xie

We examined the relationship between type 2 diabetes and skin wound healing. GSE38396 was downloaded from the Gene Expression Omnibus database and preprocessed using the RMA function of the Affy package. Differentially expressed genes (DEGs) were identified using the limma package, then DAVID was applied to perform Gene Ontology functional annotation and .. Read More»

Genet. Mol. Res. 14(2):
2015.May.11.12
DOI:
10.4238/2015.May.11.12
Animal Genetics   Research Article

A genetic analysis of post-weaning feedlot performance and profitability in Bonsmara cattle

Authors: R.R. van der Westhuizen J. van der Westhuizen S.J. Schoeman

The aim of this study was to identify factors influencing profitability in a feedlot environment and to estimate genetic parameters for and between a feedlot profit function and productive traits measured in growth tests. The heritability estimate of 0.36 for feedlot profitability shows that this trait is genetically inherited.. Read More»

Genet. Mol. Res. 8(1):
vol8-1gmr535
DOI:
10.4238/vol8-1gmr535