Haplotype
Possible association of proinflammatory cytokine IL-19 gene polymorphism with psoriasis
Authors: Wani Aadil, Bashir Ahmad Ganai, Tahseena Akhtar Tarun Narang, Rajinder Kaur
Background: Interleukin (IL-19) a member of the IL-10 family involved in abnormal keratinocyte differentiation and proliferation which is the hall mark of psoriasis. Aim: The aim of this study was to investigate the association between IL-19 gene polymorphism in patients with chronic plaque psoriasis as a factor in the susceptibility and developme.. Read More»
- Genet. Mol. Res. 18(1):
Identification of Clematidis radix et Rhizoma and its adulterants by core haplotype based on the ITS sequences
Authors: Yi-Mei Zang, Ya Gao, Ying Liu, Chun-Sheng Liu
To develop a method to identify Clematidis radix et Rhizoma using sequence similarity and sequence-specific genetic polymorphisms based on the ITS sequences. DNA was extracted from leaves of Clematis mandshurica Rupr and C. hexapetala using a DNA extraction kit. ITS sequences were amplified by PCR, and analyzed in Contig Expre.. Read More»
- Genet. Mol. Res. 17(2):
- gmr16039905
- DOI:
- 10.4238/gmr16039905
Characterization of Genetic Diversity and Linkage Disequilibrium of ZmNAC33 in Maize
Authors: Wenping Liu, Chunxiao Zhang, Shufang Li, Fengxue Jin, Wanjun Li, Xiaohui Li
The maize NAC gene, encoding a NAC domain transcription factor, plays vital roles in the growth process of maize under abiotic stresses. To investigate the response of ZmNAC33 to salinity stress, we analyzed the expression of the ZmNAC33 gene in roots and leaves of three-leaf stage seedlings among maize inbred lines. The resul.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039879
- DOI:
- 10.4238/gmr16039879
Mitochondrial DNA control region analysis of three ethnic populations in lower Northern part of Thailand
Authors: U. Suyasunanont, M. Nakkuntod and S. Mirasena
The lower northern part of Thailand contains various genetically diverse ethnic populations. The sequences of the mitochondrial DNA hypervariable region were studied in three ethnic populations inhabiting Phitsanulok Province. One hundred and nine nucleotide sequences - 53, 29, and 27 from Hmongs (Hill tribe), Lao Songs, and T.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039687
- DOI:
- 10.4238/gmr16039687
Haplotypes and polymorphism in the CCR5 gene in sickle cell disease
Authors: A.F. Nascimento, J.S. Oliveira, J.C. Silva Junior and A.A.L. Barbosa
Sickle cell disease shows several clinical manifestations in distinct levels of severity. This heterogeneity is due to the haplotype variability associated with the HbS gene, levels of fetal hemoglobin and environmental conditions, which modify the disease expression. Science community believes that the presence of a polymorph.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029675
- DOI:
- 10.4238/gmr16029675
Adjacent SNPs in the transcriptional regulatory region of the FADS2 gene associated with fatty acid and growth traits in chickens
Authors: S.K. Zhu, Y.D. Tian, S. Zhang, Q.X. Chen, Q.Y.Wang,R.L. Han and X.T. Kang
Delta-6 fatty acid desaturases are rate-limiting desaturases involved in metabolic processes of fatty acids, and they are encoded by the FADS2 gene. In the current study, an F2 resource population of Gushi chickens crossed with Anak broilers was used to investigate the genetic effects of the chicken FADS2. Two adjacent single .. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.29.11
- DOI:
- 10.4238/2014.April.29.11
Y-STR haplotype diversity and population data for Central Brazil: implications for environmental forensics and paternity testing
Authors: T.C. Vieira, M.A.D. Gigonzac, D.M. Silva, R.G. Rodovalho, G.S. Santos and A.D. da Cruz
The central region of Brazil was colonized by internal migration of individuals of different origins, who contributed to the genetic diversity existing in this population. This study determined the allele frequencies and haplotype diversity of Y-STRs in Goiás State, Central Brazil, and compared the data obtained with a .. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.April.30.1
- DOI:
- http://dx.doi.org/10.4238/2014.April.30.1
Differences in frequencies of UGT1A9, 1A7, and 1A1 genetic polymorphisms in Chinese Tibetan versus Han Chinese populations
Authors: W. Yan, Y.W. Wang, F.F. Yang, M. Wang, X.Q. Zhang, J. Dong,E. Chen and J. Yang
As part of a series of pharmacogenomics studies of the Chinese population, we investigated genetic polymorphisms of some UGT1A regions. The three genes that were analyzed were UGT1A9, 1A7, and 1A1; we sequenced their exons, together with promoters, surrounding introns and 3'-untranslated regions (3êÂ?Â?UTR) in 100 unrelated-healthy Chinese Tibetan individua.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.10.6
- DOI:
- 10.4238/2013.December.10.6
Common variants in the CRP gene are associated with serum C-reactive protein levels and body mass index in healthy individuals in Mexico
Authors: E. Flores-Alfaro, G. FernÃ?¡ndez-Tilapa, E. Salazar-MartÃ?Ânez, M. Cruz, B. Illades-Aguiar and I. Parra-Rojas
Variants in the C-reactive protein (CRP) gene have been found to be associated with various phenotypic traits. We evaluated the effect of four SNPs in the CRP gene on serum levels of protein and body mass index (BMI) in 150 unrelated Mexican subjects from 18 to 25 years old, without hypertension, non-overweight, and without inflammatory diseases, non-smok.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.May.14.5
- DOI:
- 10.4238/2012.May.14.5
Genetic characterization of the mite Varroa destructor (Acari: Varroidae) collected from honey bees Apis mellifera (Hymenoptera, Apidae) in the State of Santa Catarina, Brazil
Authors: R. Strapazzon, F.E. Carneiro, J.C.V. Guerra Jr. and G. Moretto
The mite Varroa destructor is an ectoparasite that is considered a major pest for beekeeping with European honey bees. However, Africanized bee colonies are less threatened by this ectoparasite, because infestation levels remain low in these bees. The low reproductive ability of female mites of the Japanese biotype (J), introduced to Brazil early in .. Read More»
- Genet. Mol. Res. 8(3):
- vol8-3gmr567
- DOI:
- 10.4238/vol8-3gmr567