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Haplotype

Plant Genetics   Research Article

Chloroplast diversity of Casearia grandiflora in the Cerrado of Piau�­ State

Authors: M.F. Costa, A.A. Pereira, J.B. Pinheiro, M.I. Zucchi, A.S.F. Ara�ºjo, R.L.F. Gomes, S.E.S. Valente, M.E.A. Oliveira and A.C.A. Lopes

Casearia grandiflora (Salicaceae) is a typical Cerrado species adapted to disturbed environments, making it useful for restoration projects. Knowledge of genetic diversity is important for establishing conservation strategies for this species. This study aimed to compare chloroplast haplotype diversity and structure of C. gran.. Read More»

Genet. Mol. Res. 16(1):
gmr16019572
DOI:
10.4238/gmr16019572
Human Genetics   Research Article

XRCC1 polymorphisms and haplotypes in Mexican patients with acute lymphoblastic leukemia

Authors: J.P. Meza-Espinoza, V. Peralta-Leal, M. Gutierrez-Angulo,N. Macias-Gomez, M.L. Ayala-Madrigal, P. Barros-Nu�±ez,J. Duran-Gonzalez and E. Leal-Ugarte

We examined the influence of the Arg194Trp, Arg280His, and Arg399Gln polymorphisms of XRCC1 (X-ray repair cross-complementing group 1) on the development of childhood acute lymphoblastic leukemia (ALL) in 120 ALL patients and 120 controls in Mexico. All of them were genotyped for these polymorphisms, using polymerase chain rea.. Read More»

Genet. Mol. Res. 8(4):
vol8-4gmr687
DOI:
10.4238/vol8-4gmr687
Animal Genetics   Research Article

Molecular phylogeny of the Bactrian camel based on mitochondrial Cytochrome b gene sequences

Authors: L. Ming, L. Yi, FC. Guo, S. Siriguleng and J. Jirimutu

The Bactrian camel is an important domesticated animal providing milk, meat, and other products in desert countries. In this study, 111 individuals representing 11 domestic Bactrian camel breeds from China, Mongolia, Russia, and one wild Bactrian camel group from Mongolia were selected for the preparation of mitochondrial DNA. The 1140-bp fragments of the.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038983
DOI:
10.4238/gmr.15038983
Animal Genetics   Research Article

Genome-wide association study of meat quality traits in chicken

Authors: T. Zhang, Q.C. Fan, J.Y. Wang, G.X. Zhang, Y.P. Gu and Y. Tang

Meat quality traits are very important in the poultry industry. To identify single nucleotide polymorphisms (SNPs) and candidate genes affecting meat quality traits, a genome-wide association study was performed using the Illumina chicken 60K SNP beadchip in Jinghai yellow chicken. Four meat quality traits were measured. Two SNPs reached 5% Bonferroni gen.. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.8.6
DOI:
http://dx.doi.org/10.4238/2015.September.8.6
Animal Genetics   Research Article

Polymorphism and haplotype analyses of swine leukocyte antigen DQA exons 2, 3, 4, and their associations with piglet diarrhea in Chinese native pig

Authors: X.Y. Huang, Q.L. Yang, J.H. Yuan and S.B. Gun

In this study, 290 Chinese native Yantai black pig piglets were investigated to identify gene polymorphisms, for haplotype reconstruction, and to determine the association between piglet diarrhea and swine leukocyte antigen (SLA) class II DQA exons 2, 3, and 4 by polymerase chain reaction-single stranded conformational polymorphism and cloning sequencing... Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.8.7
DOI:
http://dx.doi.org/10.4238/2015.September.8.7
Plant Genetics   Research Article

Development and characterization of single nucleotide polymorphism markers in Camellia sinensis (Theaceae)

Authors: C.C. Zhang, L.Y. Wang, K. Wei and H. Cheng

Tea is the second most popular non-alcoholic beverage in the world. In recent years, several molecular markers have been used in genetic studies of the tea plant. Yet, only a few single nucleotide polymorphisms (SNPs) have been reported. Here, we identified 818 putative SNPs from expressed sequence tag (EST) databases for the .. Read More»

Genet. Mol. Res. 13(3):
2014.April.14.10
DOI:
10.4238/2014.April.14.10
Human Genetics   Research Article

Associations of serotonin receptor gene HTR3A, HTR3B, and HTR3A haplotypes with bipolar disorder in Chinese patients

Authors: J. Jian, C. Li, J. Xu, D. Qiao, G. Mi, X. Chen and M. Tang

Single nucleotide polymorphisms (SNPs) in HTR3A and HTR3B have been reported to be associated with bipolar disorder in European and Japanese populations. We explored the roles of 21 tag SNPs in HTR3A and HTR3B in susceptibility to bipolar disorder in a Chinese cohort. Twenty-one Tag SNPs were genotyped in a study consisting of 130 patients with bipolar di.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038671
DOI:
10.4238/gmr.15038671
Plant Genetics   Research Article

Intravarietal polymorphisms reveal possible common ancestor of native Schinus terebinthifolius Raddi populations in Brazil

Authors: J.V.C. Pinto1, B.A. Crispim2, A.A. Vasconcelos3, D. Geelen4, A.B. Grisolia2 and M.C. Vieira1

Schinus terebinthifolius Raddi is a perennial native from Atlantic forest. It is of high ecological plasticity and is used in traditional medicine. Based on promising reports concerning its bioactivity, it was included as a species of great interest for distribution through the National Health System. A number of agronomic studies to guide its crop produc.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017477
DOI:
10.4238/gmr.15017477
Human Genetics   Research Article

CYP4F2 gene single nucleotide polymorphism is associated with ischemic stroke

Authors: H.-Q. Yan, Y. Yuan, P. Zhang, Z. Huang, L. Chang and Y.-K. Gui

The objective of this study was to explore the relationship between CYP4F2 gene polymorphism and ischemic stroke (IS) in the Han Chinese population. We performed a case-control study to genotype four single nucleotide polymorphisms (SNPs) (rs2108622, rs3093100, rs3093105, rs3093135) in the CYF4F2 gene. The genotype and haplotype distributions were compare.. Read More»

Genet. Mol. Res. 14(1):
2015.January.30.8
DOI:
10.4238/2015.January.30.8
Human Genetics   Research Article

Mitochondrial haplogroup D4 confers resistance and haplogroup B is a genetic risk factor for high-altitude pulmonary edema among Han Chinese

Authors: Y.J. Luo W.X. Gao S.Z. Li X.W. Huang Y. Chen F.Y. Liu Q.Y. Huang Y.Q. Gao

High-altitude pulmonary edema (HAPE) is a life-threatening condition caused by acute exposure to high altitude. Accumulating evidence suggests that genetic factors play an important role in the etiology of HAPE. However, conclusions from association studies have been hindered by limited sample size due to the rareness of this disease. It is known that mitoch.. Read More»

Genet. Mol. Res. 11(4):
2012.October.9.1
DOI:
10.4238/2012.October.9.1