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Heart

Human Genetics   Research Article

Association between RNF41 gene c.-206 T > A genetic polymorphism and risk of congenital heart diseases in the Chinese Mongolian population

Authors: Y. Zhang, S.Q. Jin, W.X. Li, G.Q. Gao, K. Zhang and J.L. Huang

This study aimed to explore the association between ring finger protein 41 (RNF41) c.-206 T > A variant and susceptibility to congenital heart disease (CHD) in the Chinese Mongolian population. The association between RNF41 gene c.-206 T > A polymorphism and CHD was examined in two independent case-control studies consis.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028089
DOI:
10.4238/gmr.15028089
Animal Genetics   Research Article

Expression of N-cadherin in myocardial tissues during the development of a rat heart

Authors: L.M. Mu, W.F. Wang, H. Zheng, Z.K. Guo and G.M. Zhang

We investigated the expression and distribution of N-cadherin during the development of a rat heart. Immunohistochemistry (IHC) was performed to detect the expression and distribution of N-cadherin in the myocardial tissues of rats at embryonic day 18 (E18d), postnatal day 5 (P5d), postnatal day 19 (P19d), postnatal day 40 (P40d), and postnatal year 1 (P1.. Read More»

Genet. Mol. Res. 14(3):
2015.August.19.22
DOI:
10.4238/2015.August.19.22
Human Genetics   Research Article

APOA5 -1131T>C and APOC3 -455T>C polymorphisms are associated with an increased risk of coronary heart disease

Authors: Y. Sun, R.B. Zhou and D.M. Chen

The aim of this study was to investigate correlations between apolipoprotein A-V (APOA5) -1131T>C and apolipoprotein C-III (APOC3) -455T>C polymorphisms and coronary heart disease (CHD). PubMed, Ovid, Cochrane Library, Embase, China National Knowledge Infrastructure, and Wanfang databases were searched using combinations of keywords relating to thes.. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.9
DOI:
10.4238/2015.December.23.9
Human Genetics   Research Article

miRNA-146a induces vascular smooth muscle cell apoptosis in a rat model of coronary heart disease via NF-�ºB pathway

Authors: Z.W. Wu, Y.F. Liu, S. Wang and B. Li

The aim of this study was to investigate the role of miRNA-146a in modulating the function of vascular smooth muscle cells in a rat model of coronary heart disease. Vascular smooth muscle cells were isolated and cultured from the rat coronary heart disease model and normal rats (controls). miRNA-146a levels were measured in vascular smooth muscle cells ob.. Read More»

Genet. Mol. Res. 14(4):
2015.December.28.19
DOI:
10.4238/2015.December.28.19
Human Genetics   Research Article

Genetic characterization of red-colored heartwood genotypes of Chinese fir using simple sequence repeat (SSR) markers

Authors: H.J. Duan, R.Y. Hu, B. Wu, D.X. Chen, K.Y. Huang, J. Dai, Q. Chen, Z.C. Wei, S. Cao, Y.H. Sun and Y. Li

The present study investigated the genetic characterization of red-colored heartwood Chinese fir [Cunninghamia lanceolata (Lamb.) Hook.] in Guangxi using 21 simple sequence repeat (SSR) markers and analyzes of the genetic variation (N = 149) in samples obtained from five sites in Guangxi Province, China. The number of different alleles and the Shannon&rsq.. Read More»

Genet. Mol. Res. 14(4):
2015.December.28.2
DOI:
10.4238/2015.December.28.2