Immune Response
Effects of porcine circovirus type 2 and pseudorabies vaccine co-inoculation on regulatory cytokine mRNA expression in pig peripheral blood mononuclear cells
Authors: F. Gao, J.-L. Xie, C.-W. Jia, H.-Y. Ren and S.-H. Zhou
We investigated the immune response effects of porcine circovirus type 2 (PCV2) on cells inoculated with pseudorabies attenuated vaccine (PRV). Real-time PCR was used to detect the mRNA expression levels of the regulatory cytokines IL-4, IL-10, IL-12p40, and IFN-γ in pig peripheral blood mononuclear cells, after in vitro.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.March.12.6
- DOI:
- http://dx.doi.org/10.4238/2014.March.12.6
Differential expression of genes during mastitis in Holstein-Zebu crossbreed dairy cows
Authors: I. Fonseca, G.R. Antunes, D.S. Paiva, C.C. Lange, S.E.F. Guimar�£es and M.F. Martins
Among the potential public health problems of animal production, infectious-contagious diseases stand out. Mastitis is among the main diseases affecting dairy cattle. One of the most promising options to reduce the problems caused by this disease, besides proper sanitary and management practices, is selective breeding of resis.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1096
- DOI:
- 10.4238/vol10-3gmr1096
Molecular cloning of HSP70 in Mycoplasma ovipneumoniae and comparison with that of other mycoplasmas
Authors: M. Li, C.J. Ma, X.M. Liu, D. Zhao, Q.C. Xu and Y.J. Wang
Mycoplasma ovipneumoniae, a bacterial species that specifically affects ovine and goat, is the cause of ovine infectious pleuropneumonia. We cloned, sequenced and analyzed heat shock protein 70 (HSP70) (dnaK) gene of M. ovipneumoniae. The full length open reading frame of the M. ovipneumoniae HSP70 gene consists of 1812 nucleo.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1193
- DOI:
- 10.4238/vol10-2gmr1193
Structure and immune expression analysis of hemoglobin genes from the blood clam Tegillarca granosa
Authors: Y.B. Bao, Q. Wang, X.M. Guo and Z.H. Lin
Hemoglobin (Hb) is the major protein component of erythrocytes in animals with red blood, although it can serve additional functions beyond the transport of oxygen. The blood clam (Tegillarca granosa) is one of the few mollusks that has Hb, although the structure and function of molluskan Hbs remain unclear. We characterized two unique and highly compartm.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.February.28.5
- DOI:
- 10.4238/2013.February.28.5
Mixture of polysaccharide and nucleic acid extracted from Bacillus Calmette-Guerin (BCG) enhances immune response of infectious bursal disease virus vaccine in chickens
Authors: X.B. Wang, Z.J. Liu, Y.J. Lv, Y. Long and E.D. Bao
In this study, the immune response induced by a mixture of polysaccharide and nucleic acid extracted from Bacillus Calmette-Guerin (BCG) was evaluated in chickens inoculated with infectious bursal disease virus (IBDV) vaccine. After the mixture was injected intramuscularly at a dose of 0.075, 0.15 or 0.3 mg·kg-1·.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15025523
- DOI:
- 10.4238/gmr.15025523
Expression of glutamine synthetase in Tegillarca granosa (Bivalvia, Arcidae) hemocytes stimulated by Vibrio parahaemolyticus and lipopolysaccharides
Authors: Y.B. Bao, L. Li, M.X. Ye, Y.H. Dong, W.X. Jin and Z.H. Lin
The blood cockle, Tegillarca granosa, is a widely consumed clam in the Indo-Pacific region. Glutamine synthetase (GS) is an enzyme that plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine. We identified the GS of T. granosa (Tg-GS) from hemocytes by 3'- and 5'-rapid amplification .. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.10.9
- DOI:
- 10.4238/2013.April.10.9
Akirin2 expression in response to vaccine-induced immunity in chicken
Authors: C.L. Man, W.T. Mu, Y. Chang and D.X. Zhao
Akirin2 is a nuclear factor that plays an important role in the development and regulation of innate immune response. In this study, akirin2 gene expression in several primary immune organs (liver, thymus, and bursa) of Hi-Line Brown chicken administered with the LoSota vaccine was analyzed during the various stages of increase in Newcastle disease virus .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.21.20
- DOI:
- 10.4238/2015.December.21.20