Klf6
The Disruption of Klf6-Related Super-Enhancer Induces Growth Inhibition and Apoptosis in Human HepG2 Cells
Authors: KumChol Ri, KumChol Kim, SunHyok Kong, JuHua Ri
Klf6 is a member of the Krüppel-like factor family, which is a group of zinc finger transcription factors involved in differentiation and development. In general, Klf6 gene plays an important role in growth-related signal transduction pathways, cell proliferation, apoptosis, and angiogenesis. Recently, the Klf6 gene is co.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039888
- DOI:
- 10.4238/gmr16039888
Identification of Klf6-Related Super Enhancer in Human Hepatoma (HepG2) Cells by CRISPR Technique
Authors: Kum Chol Ri*, Jong Su Kim, Chol Kim
The Klf6 gene is a tumor suppressor gene belonging to the family of the Klf gene and closely associated with tumor formation. Recently, super enhancers(SEs) have been shown to play a particularly important role in regulating cell identity and are attempting to evaluate the in vivo function of SEs. But direct functional evidenc.. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039841
- DOI:
- 10.4238/gmr16039841