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Lncrna

Medical Genetics   Research Article

Expression analysis of OIP5-AS1 in bladder tissues

Authors: Feraydoon Abdolmaleki, Soudeh Ghafoui-Fard, Mohammad Taheri, Alireza Mordadi, Mandana Afasharpad, Abolghasem Nikfallah, Bashir Nazparvar, Vahid Kholghi Oskooei, Mir Davood Omrani

Long non-coding RNAs (lncRNAs) have crucial roles in regulation of many aspects of cell functions which are related with carcinogenesis process. The lncRNA Opa Interacting Protein 5-antisense 1 (OIP5-AS1) is among lncRNAs whose roles in some human malignancies have been elucidated. In the current study, we aimed at identification of the role of this lncRN.. Read More»

Genet. Mol. Res. 18(1):
Medical Genetics   Review Article

Long non-coding RNA-protein interaction: the preliminary step to track their biological functions

Authors: Amr. R. Ghanam, Wafa Ali, Mohnad Abdalla

RNA is not only an intermediate for the flow of genetic information between DNA and protein. The transcription of the entire genomes generates a myriad non-protein coding RNA in addition to protein coding genes. Among these transcripts, lncRNA which is the least well understood and they cannot be considered as merely transcriptional noises. Here, we revie.. Read More»

Genet. Mol. Res. 17(4):
http://dx.doi.org/gmr16039920
DOI:
http://dx.doi.org/10.4238/gmr16039920
Human Genetics   Research Article

Long non-coding RNA ENST00000457645 reverses cisplatin resistance in CP70 ovarian cancer cells

Authors: H. Yan, J.Y. Xia and F.Z. Feng

The objective of this study was to investigate the effect of downregulating long non-coding RNAs (lncRNAs) on the reversal of cisplatin resistance in CP70 ovarian cancer cells, and to identify the underlying mechanism(s) of action. An lncRNA microarray was performed to screen for downregulated lncRNAs in cisplatin-resistant CP.. Read More»

Genet. Mol. Res. 16(1):
gmr16019411
DOI:
10.4238/gmr16019411